49 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	polk	Polymerase (DNA directed) kappa. (401 aa)
	fancg	FA complementation group G. (600 aa)
	LOC108247643	CREB binding protein b. (2428 aa)
	rpa3	Replication protein A 14kDa subunit. (122 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (396 aa)
	cry1	Cryptochrome 1-like 4. (568 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	apex1	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (310 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	ddb2	Damage-specific DNA binding protein 2. (497 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa)
	LOC108241482	CREB binding protein a. (2490 aa)
	polh	Polymerase (DNA directed), eta. (738 aa)
	neil1	Nei-like DNA glycosylase 1. (410 aa)
	dclre1a	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (907 aa)
	nthl1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (323 aa)
	brca1	Uncharacterized protein. (1354 aa)
	Rbbp8	SAE2 domain-containing protein. (82 aa)
	blm	BLM RecQ like helicase. (1384 aa)
	ung	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (315 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa)
	ogg1	8-oxoguanine DNA glycosylase. (410 aa)
	ep300	E1A binding protein p300 b. (2785 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	rev1	REV1 DNA directed polymerase. (1363 aa)
	xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa)
	MUTYH	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (468 aa)
	ddb1	Damage-specific DNA binding protein 1. (1075 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (935 aa)
	nbn	Nibrin. (832 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
	Aunip	Uncharacterized protein. (335 aa)
	pot1	Protection of telomeres 1 homolog. (770 aa)
	LOC108250440	E1A binding protein p300 a. (2399 aa)
	sirt6	Sirtuin 6. (350 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1702 aa)
	dclre1b	DNA cross-link repair 1B. (573 aa)
	poli	Polymerase (DNA directed) iota. (716 aa)
	rad23a	RAD23 homolog A, nucleotide excision repair protein a. (365 aa)
	dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (411 aa)
	recql4	RecQ helicase-like 4. (1281 aa)
	LOC108236679	Nei-like DNA glycosylase 3. (556 aa)
	pold1	DNA polymerase. (1105 aa)
	LOC108230341	Cryptochrome DASH. (521 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
	LOC108233302	Cryptochrome circadian regulator 1a. (627 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108236679	MUTYH	ENSKMAP00000013215	ENSKMAP00000003083	Nei-like DNA glycosylase 3.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.731
LOC108236679	blm	ENSKMAP00000013215	ENSKMAP00000022385	Nei-like DNA glycosylase 3.	BLM RecQ like helicase.	0.509
LOC108236679	ercc1	ENSKMAP00000013215	ENSKMAP00000027419	Nei-like DNA glycosylase 3.	Excision repair cross-complementation group 1.	0.434
LOC108236679	ercc2	ENSKMAP00000013215	ENSKMAP00000028774	Nei-like DNA glycosylase 3.	Excision repair cross-complementation group 2.	0.415
LOC108236679	neil1	ENSKMAP00000013215	ENSKMAP00000025275	Nei-like DNA glycosylase 3.	Nei-like DNA glycosylase 1.	0.662
LOC108236679	nthl1	ENSKMAP00000013215	ENSKMAP00000024806	Nei-like DNA glycosylase 3.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.864
LOC108236679	ogg1	ENSKMAP00000013215	ENSKMAP00000021116	Nei-like DNA glycosylase 3.	8-oxoguanine DNA glycosylase.	0.664
LOC108236679	polh	ENSKMAP00000013215	ENSKMAP00000025604	Nei-like DNA glycosylase 3.	Polymerase (DNA directed), eta.	0.411
LOC108236679	poli	ENSKMAP00000013215	ENSKMAP00000010639	Nei-like DNA glycosylase 3.	Polymerase (DNA directed) iota.	0.411
LOC108236679	polk	ENSKMAP00000013215	ENSKMAP00000016102	Nei-like DNA glycosylase 3.	Polymerase (DNA directed) kappa.	0.411
LOC108236679	recql4	ENSKMAP00000013215	ENSKMAP00000012780	Nei-like DNA glycosylase 3.	RecQ helicase-like 4.	0.491
LOC108236679	rev1	ENSKMAP00000013215	ENSKMAP00000001976	Nei-like DNA glycosylase 3.	REV1 DNA directed polymerase.	0.411
LOC108236679	ung	ENSKMAP00000013215	ENSKMAP00000022300	Nei-like DNA glycosylase 3.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.693
LOC108236679	xrcc1	ENSKMAP00000013215	ENSKMAP00000026769	Nei-like DNA glycosylase 3.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.581
LOC108241482	LOC108247643	ENSKMAP00000026436	ENSKMAP00000019200	CREB binding protein a.	CREB binding protein b.	0.901
LOC108241482	LOC108250440	ENSKMAP00000026436	ENSKMAP00000008734	CREB binding protein a.	E1A binding protein p300 a.	0.928
LOC108241482	apex1	ENSKMAP00000026436	ENSKMAP00000028558	CREB binding protein a.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.420
LOC108241482	brca1	ENSKMAP00000026436	ENSKMAP00000024393	CREB binding protein a.	Uncharacterized protein.	0.717
LOC108241482	ep300	ENSKMAP00000026436	ENSKMAP00000020640	CREB binding protein a.	E1A binding protein p300 b.	0.992
LOC108241482	xpa	ENSKMAP00000026436	ENSKMAP00000028000	CREB binding protein a.	Xeroderma pigmentosum, complementation group A.	0.717