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| | smarcal1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (868 aa) |
| | ercc5 | Excision repair cross-complementation group 5. (1028 aa) |
| | smc2 | Structural maintenance of chromosomes protein. (1200 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | ercc4 | Excision repair cross-complementation group 4. (899 aa) |
| | LOC108237534 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (746 aa) |
| | fbh1 | F-box DNA helicase 1. (1108 aa) |
| | stn1 | STN1 subunit of CST complex. (315 aa) |
| | LOC108241559 | Uncharacterized protein. (560 aa) |
| | top1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (748 aa) |
| | rad18 | RAD18 E3 ubiquitin protein ligase. (490 aa) |
| | ercc1 | Excision repair cross-complementation group 1. (352 aa) |
| | smc4 | Structural maintenance of chromosomes protein. (1255 aa) |
| | ighmbp2 | Immunoglobulin mu DNA binding protein 2. (978 aa) |
| | LOC108244389 | SET domain and mariner transposase fusion gene. (287 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | wdr48 | WD repeat domain 48b. (677 aa) |
| | dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1105 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | terf2 | HTH myb-type domain-containing protein. (603 aa) |
| | LOC108235131 | SAM domain and HD domain 1. (624 aa) |
| | LOC108235292 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | nabp1 | Nucleic acid binding protein 1a. (219 aa) |
| | ENSKMAP00000024065 | Helicase ATP-binding domain-containing protein. (279 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | LOC108231059 | Far upstream element (FUSE) binding protein 3. (527 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | sprtn | SprT-like N-terminal domain. (569 aa) |
| | rtf1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (677 aa) |
| | LOC108251266 | Endo/exonuclease/phosphatase domain-containing protein. (311 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | bivm | Basic, immunoglobulin-like variable motif containing. (481 aa) |
| | rexo4 | REX4 homolog, 3'-5' exonuclease. (415 aa) |
| | pola1 | DNA polymerase. (1476 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | ssbp1 | Single-stranded DNA binding protein 1. (146 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (984 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | LOC108235069 | LisH domain-containing protein. (383 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | ssbp2 | Si:ch211-130m23.3. (374 aa) |
| | ten1 | TEN1 subunit of CST complex. (135 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (382 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (820 aa) |
| | nup35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (297 aa) |
| | polr2g | Polymerase (RNA) II (DNA directed) polypeptide G-like. (189 aa) |
| | hrob | Si:dkey-260c8.8. (670 aa) |
| | LOC108236679 | Nei-like DNA glycosylase 3. (556 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (848 aa) |
| | lonp1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (998 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | polr2h | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) |
| | ENSKMAP00000010500 | Uncharacterized protein. (850 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | swsap1 | SWIM-type zinc finger 7 associated protein 1. (278 aa) |
| | terf1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (366 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | twnk | Twinkle mtDNA helicase. (717 aa) |
| | hmces | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (365 aa) |
| | tdp2 | Tyrosyl-DNA phosphodiesterase 2b. (360 aa) |
| | pot1 | Protection of telomeres 1 homolog. (770 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | radx | RPA1 related single stranded DNA binding protein. (771 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (781 aa) |
| | ctc1 | Uncharacterized protein. (993 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | tsn | Translin. (227 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (572 aa) |
| | lrpprc | Leucine-rich pentatricopeptide repeat containing. (1644 aa) |
| | LOC108230802 | Single stranded DNA binding protein 4. (385 aa) |
| | xpc | Xeroderma pigmentosum, complementation group C. (935 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1212 aa) |
| | LOC108228663 | Myelin expression factor 2. (566 aa) |
| | LOC108230815 | Single stranded DNA binding protein 3b. (390 aa) |
| | polr3c | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (545 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (609 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
