STRINGSTRING
ercc5 ercc5 LOC108250843 LOC108250843 dicer1 dicer1 aplf aplf mus81 mus81 LOC108244487 LOC108244487 dffb dffb fen1 fen1 LOC108249143 LOC108249143 endog endog LOC108242278 LOC108242278 LOC108234261 LOC108234261 tatdn1 tatdn1 ENSKMAP00000011592 ENSKMAP00000011592 gen1 gen1 mre11 mre11 LOC108234386 LOC108234386 LOC108234321 LOC108234321 ENDOV ENDOV exo1 exo1 zranb3 zranb3 rad51c rad51c LOC108246009 LOC108246009 bivm bivm LOC108236762 LOC108236762 dnase1 dnase1 LOC108244389 LOC108244389 DNA2 DNA2 apex1 apex1 LOC108245565 LOC108245565 LOC108245566 LOC108245566 fan1 fan1 ercc4 ercc4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc5Excision repair cross-complementation group 5. (1028 aa)
LOC108250843Deoxyribonuclease; Belongs to the DNase I family. (310 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1678 aa)
aplfUncharacterized protein. (413 aa)
mus81MUS81 structure-specific endonuclease subunit. (556 aa)
LOC108244487Zgc:110269. (346 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (346 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
LOC108249143Si:ch211-133n4.4. (318 aa)
endogEndonuclease. (296 aa)
LOC108242278Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa)
LOC108234261Zgc:85936. (1161 aa)
tatdn1TatD DNase domain containing 1. (311 aa)
ENSKMAP00000011592Uncharacterized protein. (216 aa)
gen1Chromo_2 domain-containing protein. (574 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa)
LOC108234386Deoxyribonuclease II beta. (398 aa)
LOC108234321Uncharacterized protein. (357 aa)
ENDOVEndonuclease V. (285 aa)
exo1Exonuclease 1. (769 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (984 aa)
rad51cRAD51 paralog C. (342 aa)
LOC108246009Deoxyribonuclease II, lysosomal. (371 aa)
bivmBasic, immunoglobulin-like variable motif containing. (481 aa)
LOC108236762Deoxyribonuclease; Belongs to the DNase I family. (295 aa)
dnase1Deoxyribonuclease; Belongs to the DNase I family. (295 aa)
LOC108244389SET domain and mariner transposase fusion gene. (287 aa)
DNA2DNA replication helicase/nuclease 2. (1388 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (310 aa)
LOC108245565Uncharacterized protein. (394 aa)
LOC108245566Uncharacterized protein. (390 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (969 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.