STRINGSTRING
MUTYH MUTYH ENSKMAP00000003368 ENSKMAP00000003368 ENSKMAP00000003870 ENSKMAP00000003870 polg polg polb polb ENSKMAP00000005142 ENSKMAP00000005142 fen1 fen1 huwe1 huwe1 ENSKMAP00000007694 ENSKMAP00000007694 hmga2 hmga2 usp47 usp47 tdg tdg LOC108245718 LOC108245718 apex2 apex2 sirt6 sirt6 ENSKMAP00000009473 ENSKMAP00000009473 ENSKMAP00000012338 ENSKMAP00000012338 LOC108236679 LOC108236679 pold1 pold1 ENSKMAP00000015044 ENSKMAP00000015044 lig3 lig3 ENSKMAP00000019528 ENSKMAP00000019528 rpa3 rpa3 Pole Pole ENSKMAP00000020750 ENSKMAP00000020750 ogg1 ogg1 ENSKMAP00000021350 ENSKMAP00000021350 ung ung lig1 lig1 smug1 smug1 parp2 parp2 mpg mpg nthl1 nthl1 neil1 neil1 xrcc1 xrcc1 ercc6 ercc6 ENSKMAP00000027669 ENSKMAP00000027669 DNA2 DNA2 xpa xpa poll poll apex1 apex1 LOC108235861 LOC108235861 ENSKMAP00000029904 ENSKMAP00000029904
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (468 aa)
ENSKMAP00000003368Reverse transcriptase domain-containing protein. (1272 aa)
ENSKMAP00000003870Uncharacterized protein. (462 aa)
polgPolymerase (DNA directed), gamma. (1203 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
ENSKMAP00000005142Uncharacterized protein. (266 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4192 aa)
ENSKMAP00000007694Endo/exonuclease/phosphatase domain-containing protein. (465 aa)
hmga2Uncharacterized protein. (115 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
tdgThymine DNA glycosylase, tandem duplicate 1. (444 aa)
LOC108245718Thymine DNA glycosylase, tandem duplicate 2. (387 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (553 aa)
sirt6Sirtuin 6. (350 aa)
ENSKMAP00000009473Reverse transcriptase domain-containing protein. (1270 aa)
ENSKMAP00000012338Reverse transcriptase domain-containing protein. (815 aa)
LOC108236679Nei-like DNA glycosylase 3. (556 aa)
pold1DNA polymerase. (1105 aa)
ENSKMAP00000015044Uncharacterized protein. (128 aa)
lig3DNA ligase. (1011 aa)
ENSKMAP00000019528annotation not available (774 aa)
rpa3Replication protein A 14kDa subunit. (122 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (298 aa)
ENSKMAP00000020750DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (314 aa)
ogg18-oxoguanine DNA glycosylase. (410 aa)
ENSKMAP00000021350Uncharacterized protein. (364 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (315 aa)
lig1DNA ligase. (1010 aa)
smug1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (275 aa)
parp2Poly [ADP-ribose] polymerase. (655 aa)
mpgN-methylpurine DNA glycosylase. (273 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (323 aa)
neil1Nei-like DNA glycosylase 1. (410 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa)
ercc6Excision repair cross-complementation group 6. (1442 aa)
ENSKMAP00000027669Reverse transcriptase domain-containing protein. (1264 aa)
DNA2DNA replication helicase/nuclease 2. (1388 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (571 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (310 aa)
LOC108235861Si:ch211-141o9.10. (273 aa)
ENSKMAP00000029904Uncharacterized protein. (444 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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