Your Input: | |
| | pnkp | Polynucleotide kinase 3'-phosphatase. (590 aa) |
| | polq | Polymerase (DNA directed), theta. (2148 aa) |
| | ENSKMAP00000000178 | Reverse transcriptase domain-containing protein. (1096 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | ENSKMAP00000000423 | Reverse transcriptase domain-containing protein. (1066 aa) |
| | ENSKMAP00000000467 | TAN domain-containing protein. (123 aa) |
| | Atm | Uncharacterized protein. (130 aa) |
| | ENSKMAP00000000943 | Uncharacterized protein. (144 aa) |
| | ENSKMAP00000001130 | Reverse transcriptase domain-containing protein. (1110 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (609 aa) |
| | lig4 | DNA ligase. (922 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa) |
| | mfsd11 | Major facilitator superfamily domain containing 11. (454 aa) |
| | LOC108246201 | Essential meiotic structure-specific endonuclease 1. (533 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | RAD21 | RAD21 cohesin complex component. (642 aa) |
| | cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (547 aa) |
| | aplf | Uncharacterized protein. (413 aa) |
| | paxx | PAXX non-homologous end joining factor. (191 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (556 aa) |
| | ENSKMAP00000003442 | Reverse transcriptase domain-containing protein. (1237 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1212 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (572 aa) |
| | nbn | Nibrin. (832 aa) |
| | prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4049 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (938 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (781 aa) |
| | ENSKMAP00000007476 | BRCT domain-containing protein. (138 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | LOC108242278 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa) |
| | ENSKMAP00000007722 | RAD21 cohesin complex component like 1. (496 aa) |
| | LOC108248076 | Checkpoint kinase 2. (534 aa) |
| | ENSKMAP00000008060 | Reverse transcriptase domain-containing protein. (975 aa) |
| | LOC108244568 | RING-type domain-containing protein. (223 aa) |
| | LOC108244555 | Zgc:66440. (369 aa) |
| | ENSKMAP00000008309 | Reverse transcriptase domain-containing protein. (1265 aa) |
| | Aunip | Uncharacterized protein. (335 aa) |
| | ENSKMAP00000008781 | Reverse transcriptase domain-containing protein. (1162 aa) |
| | tdp2 | Tyrosyl-DNA phosphodiesterase 2b. (360 aa) |
| | hmces | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (365 aa) |
| | ENSKMAP00000009231 | Reverse transcriptase domain-containing protein. (987 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | sirt6 | Sirtuin 6. (350 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1702 aa) |
| | ENSKMAP00000009514 | Reverse transcriptase domain-containing protein. (489 aa) |
| | smc5 | Structural maintenance of chromosomes 5. (1078 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (712 aa) |
| | swsap1 | SWIM-type zinc finger 7 associated protein 1. (278 aa) |
| | dclre1b | DNA cross-link repair 1B. (573 aa) |
| | iffo1 | Intermediate filament family orphan 1b; Belongs to the intermediate filament family. (628 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | LOC108246144 | Uncharacterized protein. (893 aa) |
| | LOC108234261 | Zgc:85936. (1161 aa) |
| | LOC108251734 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (597 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (637 aa) |
| | ap5s1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | ENSKMAP00000011321 | annotation not available (1265 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | ENSKMAP00000011592 | Uncharacterized protein. (216 aa) |
| | gen1 | Chromo_2 domain-containing protein. (574 aa) |
| | tonsl | Tonsoku-like, DNA repair protein. (1413 aa) |
| | xrcc4 | X-ray repair complementing defective repair in Chinese hamster cells 4. (343 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (996 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1335 aa) |
| | fancm | Helicase C-terminal domain-containing protein. (1616 aa) |
| | ENSKMAP00000012494 | Helicase ATP-binding domain-containing protein. (418 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (411 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | ENSKMAP00000013203 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (207 aa) |
| | iffo2 | Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (486 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | prpf19 | Pre-mRNA processing factor 19. (505 aa) |
| | Brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (263 aa) |
| | uvrag | UV radiation resistance associated gene. (728 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (820 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (382 aa) |
| | ddx1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa) |
| | LOC108234481 | Uncharacterized protein. (270 aa) |
| | parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa) |
| | swi5 | SWI5 homologous recombination repair protein. (136 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | psmd14 | Uncharacterized protein. (689 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa) |
| | hsf2bp | Heat shock transcription factor 2 binding protein. (321 aa) |
| | actr5 | Actin related protein 5; Belongs to the actin family. (642 aa) |
| | zswim7 | Zinc finger, SWIM-type containing 7. (138 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | ENSKMAP00000017454 | Reverse transcriptase domain-containing protein. (1273 aa) |
| | lig3 | DNA ligase. (1011 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (374 aa) |
| | vcp | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | uimc1 | Uncharacterized protein. (976 aa) |
| | EME2 | ERCC4 domain-containing protein. (416 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | trip13 | Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (422 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (381 aa) |
| | ENSKMAP00000019521 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | ENSKMAP00000019606 | Reverse transcriptase domain-containing protein. (1217 aa) |
| | ercc8 | Excision repair cross-complementation group 8. (401 aa) |
| | rad51c | RAD51 paralog C. (342 aa) |
| | smchd1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1800 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | ENSKMAP00000020023 | annotation not available (828 aa) |
| | pola1 | DNA polymerase. (1476 aa) |
| | ENSKMAP00000020407 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | nhej1 | Nonhomologous end-joining factor 1. (308 aa) |
| | LOC108251266 | Endo/exonuclease/phosphatase domain-containing protein. (311 aa) |
| | dntt | Deoxynucleotidyltransferase, terminal; Belongs to the DNA polymerase type-X family. (432 aa) |
| | ENSKMAP00000021337 | Reverse transcriptase domain-containing protein. (876 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (2448 aa) |
| | ENSKMAP00000021513 | Reverse transcriptase domain-containing protein. (1156 aa) |
| | ENSKMAP00000021569 | Reverse transcriptase domain-containing protein. (1121 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (357 aa) |
| | zfyve26 | Zinc finger, FYVE domain containing 26. (2585 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (564 aa) |
| | ap5z1 | Adaptor related protein complex 5 subunit zeta 1. (660 aa) |
| | abraxas1 | Abraxas 1, BRCA1 A complex subunit. (349 aa) |
| | helq | Helicase, POLQ like. (1012 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | LOC108228450 | Histone PARylation factor 1. (314 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | LOC108231013 | Nipped-B protein. (2617 aa) |
| | ENSKMAP00000023736 | Reverse transcriptase domain-containing protein. (885 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | ENSKMAP00000023965 | Uncharacterized protein. (240 aa) |
| | fancb | FA complementation group B. (776 aa) |
| | parp2 | Poly [ADP-ribose] polymerase. (655 aa) |
| | nabp1 | Nucleic acid binding protein 1a. (219 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | LOC108249571 | Si:dkey-3h3.3. (421 aa) |
| | ENSKMAP00000024676 | Reverse transcriptase domain-containing protein. (1254 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (515 aa) |
| | LOC108235131 | SAM domain and HD domain 1. (624 aa) |
| | Cdca5 | Cell division cycle associated 5. (265 aa) |
| | dclre1a | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (907 aa) |
| | LOC108241508 | Zgc:136908; Belongs to the AAA ATPase family. (808 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | LOC108243680 | Uncharacterized protein. (420 aa) |
| | rmi2 | RecQ mediated genome instability 2. (145 aa) |
| | LOC108242664 | Intermediate filament family orphan 1a; Belongs to the intermediate filament family. (628 aa) |
| | ino80 | INO80 complex ATPase subunit. (1474 aa) |
| | wdr48 | WD repeat domain 48b. (677 aa) |
| | Meioc | Uncharacterized protein. (730 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa) |
| | LOC108239429 | SEM1 26S proteasome complex subunit. (68 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1442 aa) |
| | LOC108244389 | SET domain and mariner transposase fusion gene. (287 aa) |
| | ercc1 | Excision repair cross-complementation group 1. (352 aa) |
| | ENSKMAP00000027458 | Reverse transcriptase domain-containing protein. (1256 aa) |
| | nipbl | Nipped-B protein. (2547 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1388 aa) |
| | LOC108241443 | Calcyon neuron-specific vesicular protein. (205 aa) |
| | nsmce1 | NSE1 homolog, SMC5-SMC6 complex component. (247 aa) |
| | fancd2 | FA complementation group D2. (1361 aa) |
| | parp3 | Poly [ADP-ribose] polymerase. (530 aa) |
| | ENSKMAP00000028001 | Reverse transcriptase domain-containing protein. (874 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa) |
| | LOC108232185 | RAD21 cohesin complex component a. (636 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (571 aa) |
| | nsmce2 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (228 aa) |
| | smarcad1 | Uncharacterized protein. (1062 aa) |
| | fbh1 | F-box DNA helicase 1. (1108 aa) |
| | MARF1 | Meiosis regulator and mRNA stability factor 1. (1814 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (969 aa) |
| | ercc4 | Excision repair cross-complementation group 4. (899 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | ENSKMAP00000029997 | Reverse transcriptase domain-containing protein. (1252 aa) |
