Your Input: | |
| | ENSKMAP00000003287 | Chemokine (C-C motif) receptor 6b. (353 aa) |
| | rag2 | Recombination activating gene 2. (533 aa) |
| | rag1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1071 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (556 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1212 aa) |
| | brip1 | BRCA1 interacting protein C-terminal helicase 1. (1177 aa) |
| | tex11 | Testis expressed 11. (806 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (572 aa) |
| | nbn | Nibrin. (832 aa) |
| | prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4049 aa) |
| | C1orf146 | Chromosome 1 open reading frame 146. (168 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | msh4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (866 aa) |
| | msh5 | MutS homolog 5. (654 aa) |
| | tfpt | TCF3 (E2A) fusion partner. (197 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (938 aa) |
| | ino80c | INO80 complex subunit C. (207 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (781 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | LOC108242278 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa) |
| | ENSKMAP00000007722 | RAD21 cohesin complex component like 1. (496 aa) |
| | Aunip | Uncharacterized protein. (335 aa) |
| | aicda | Activation-induced cytidine deaminase. (211 aa) |
| | mnd1 | Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (208 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | apex2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (553 aa) |
| | ENSKMAP00000009348 | Histone H2A; Belongs to the histone H2A family. (135 aa) |
| | smc5 | Structural maintenance of chromosomes 5. (1078 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (712 aa) |
| | swsap1 | SWIM-type zinc finger 7 associated protein 1. (278 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | ENSKMAP00000010652 | Histone H2A; Belongs to the histone H2A family. (146 aa) |
| | LOC108246144 | Uncharacterized protein. (893 aa) |
| | LOC108234261 | Zgc:85936. (1161 aa) |
| | ENSKMAP00000010784 | annotation not available (146 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (637 aa) |
| | ENSKMAP00000010962 | Histone H2A; Belongs to the histone H2A family. (134 aa) |
| | ap5s1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | tprkb | Tp53rk binding protein; Belongs to the CGI121/TPRKB family. (175 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | ENSKMAP00000011592 | Uncharacterized protein. (216 aa) |
| | gen1 | Chromo_2 domain-containing protein. (574 aa) |
| | tonsl | Tonsoku-like, DNA repair protein. (1413 aa) |
| | ENSKMAP00000011726 | Histone H2A; Belongs to the histone H2A family. (134 aa) |
| | xrcc4 | X-ray repair complementing defective repair in Chinese hamster cells 4. (343 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (996 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1335 aa) |
| | fancm | Helicase C-terminal domain-containing protein. (1616 aa) |
| | ENSKMAP00000012494 | Helicase ATP-binding domain-containing protein. (418 aa) |
| | ino80e | INO80 complex subunit E. (250 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (411 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | Syce3 | Uncharacterized protein. (83 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (207 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | hrob | Si:dkey-260c8.8. (670 aa) |
| | top2a | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1539 aa) |
| | cenpx | Centromere protein X. (81 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | ENSKMAP00000014889 | Si:dkey-119f1.1. (1095 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (820 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (382 aa) |
| | LOC108234481 | Uncharacterized protein. (270 aa) |
| | actr8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (643 aa) |
| | ENSKMAP00000015489 | HATPase_c domain-containing protein. (252 aa) |
| | swi5 | SWI5 homologous recombination repair protein. (136 aa) |
| | rhno1 | Si:ch73-352p4.5. (290 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | psmd14 | Uncharacterized protein. (689 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa) |
| | hsf2bp | Heat shock transcription factor 2 binding protein. (321 aa) |
| | uchl5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | actr5 | Actin related protein 5; Belongs to the actin family. (642 aa) |
| | zswim7 | Zinc finger, SWIM-type containing 7. (138 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | lig3 | DNA ligase. (1011 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | exo1 | Exonuclease 1. (769 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (374 aa) |
| | hdac10 | Histone deacetylase 10. (663 aa) |
| | rpain | RPA interacting protein. (227 aa) |
| | EME2 | ERCC4 domain-containing protein. (416 aa) |
| | batf | Basic leucine zipper transcription factor, ATF-like. (124 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | trip13 | Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (422 aa) |
| | ENSKMAP00000019155 | Histone H2A; Belongs to the histone H2A family. (137 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa) |
| | LOC108229151 | TOP4c domain-containing protein. (301 aa) |
| | rad51c | RAD51 paralog C. (342 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | LOC108251250 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | nsmce4a | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (351 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | nhej1 | Nonhomologous end-joining factor 1. (308 aa) |
| | smc6 | Structural maintenance of chromosomes 6. (1092 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (2448 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (357 aa) |
| | zfyve26 | Zinc finger, FYVE domain containing 26. (2585 aa) |
| | ap5z1 | Adaptor related protein complex 5 subunit zeta 1. (660 aa) |
| | kiaa1841 | Si:ch211-189k9.2. (701 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa) |
| | helq | Helicase, POLQ like. (1012 aa) |
| | ung | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (315 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | lig1 | DNA ligase. (1010 aa) |
| | LOC108231013 | Nipped-B protein. (2617 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1564 aa) |
| | rec114 | Uncharacterized protein. (180 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | fancb | FA complementation group B. (776 aa) |
| | LOC108228507 | ATP-dependent DNA helicase; Belongs to the helicase family. (1236 aa) |
| | psmc3ip | PSMC3 interacting protein. (212 aa) |
| | nabp1 | Nucleic acid binding protein 1a. (219 aa) |
| | ENSKMAP00000024388 | TROVE domain-containing protein. (983 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | exosc3 | Exosome component 3. (244 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (515 aa) |
| | LOC108235131 | SAM domain and HD domain 1. (624 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | rmi2 | RecQ mediated genome instability 2. (145 aa) |
| | ino80 | INO80 complex ATPase subunit. (1474 aa) |
| | wdr48 | WD repeat domain 48b. (677 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | CCNB1IP1 | Cyclin B1 interacting protein 1. (311 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa) |
| | tcf7 | Transcription factor 7. (384 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | LOC108244955 | LisH domain-containing protein. (1493 aa) |
| | LOC108239429 | SEM1 26S proteasome complex subunit. (68 aa) |
| | ercc1 | Excision repair cross-complementation group 1. (352 aa) |
| | nipbl | Nipped-B protein. (2547 aa) |
| | LOC108241443 | Calcyon neuron-specific vesicular protein. (205 aa) |
| | nsmce1 | NSE1 homolog, SMC5-SMC6 complex component. (247 aa) |
| | fancd2 | FA complementation group D2. (1361 aa) |
| | supv3l1 | SUV3-like helicase. (777 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa) |
| | LOC108232185 | RAD21 cohesin complex component a. (636 aa) |
| | msh3 | MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (972 aa) |
| | ENSKMAP00000003159 | Helicase for meiosis 1. (969 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1179 aa) |
| | cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (547 aa) |
| | RAD21 | RAD21 cohesin complex component. (642 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | LOC108246201 | Essential meiotic structure-specific endonuclease 1. (533 aa) |
| | lef1 | Lymphoid enhancer-binding factor 1. (379 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa) |
| | pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (626 aa) |
| | LOC108231281 | CD40 ligand; Belongs to the tumor necrosis factor family. (267 aa) |
| | lig4 | DNA ligase. (922 aa) |
| | Atm | Uncharacterized protein. (130 aa) |
| | ENSKMAP00000000467 | TAN domain-containing protein. (123 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | pgbd5 | PiggyBac transposable element derived 5. (536 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (571 aa) |
| | nsmce2 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (228 aa) |
| | atad5 | ATPase family AAA domain containing 5a. (1804 aa) |
| | fbh1 | F-box DNA helicase 1. (1108 aa) |
| | pagr1 | PAXIP1 associated glutamate-rich protein 1. (274 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (969 aa) |
| | ercc4 | Excision repair cross-complementation group 4. (899 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | hdgfl2 | HDGF like 2. (661 aa) |
