(28 nodes) Motor neuron axon guidance network (Kryptolebias marmoratus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108236300	Notum pectinacetylesterase 2. (523 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	tmem41b	Transmembrane protein 41B. (283 aa)
	LOC108229538	Uncharacterized protein. (107 aa)
	LOC108231368	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	rest	RE1-silencing transcription factor. (996 aa)
	LOC108240515	Uncharacterized protein. (188 aa)
	ENSKMAP00000009644	Ras homolog gene family, member Gd. (95 aa)
	LOC108236452	Survival of motor neuron 1, telomeric. (282 aa)
	LOC108246957	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (913 aa)
	LOC108241812	Netrin 5. (840 aa)
	chst11	Carbohydrate sulfotransferase. (361 aa)
	LOC108231039	Ring finger protein 165a. (345 aa)
	chodl	Chondrolectin. (298 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (1077 aa)
	LOC108236217	Netrin 1b. (738 aa)
	nkx2-2	NK2 homeobox 2a. (311 aa)
	LOC108230078	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (799 aa)
	LOC108237126	Netrin 2. (634 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
	LOC108235111	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (864 aa)
	e2f8	E2F transcription factor 8. (864 aa)
	LOC108244397	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (804 aa)
	LOC108244970	E2F transcription factor 7. (615 aa)
	LOC108230164	Protein phosphatase 1 regulatory subunit. (910 aa)
	LOC108233736	Ring finger protein 165b. (348 aa)
	NTN1	Netrin 1. (613 aa)
	lhx1	LIM homeobox 1a. (407 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC108246957	ENSKMAP00000018850	ENSKMAP00000012433	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
ENSKMAP00000009644	LOC108229538	ENSKMAP00000009644	ENSKMAP00000008124	Ras homolog gene family, member Gd.	Uncharacterized protein.	0.964
ENSKMAP00000009644	LOC108240515	ENSKMAP00000009644	ENSKMAP00000009555	Ras homolog gene family, member Gd.	Uncharacterized protein.	0.902
LOC108229538	ENSKMAP00000009644	ENSKMAP00000008124	ENSKMAP00000009644	Uncharacterized protein.	Ras homolog gene family, member Gd.	0.964
LOC108229538	LOC108240515	ENSKMAP00000008124	ENSKMAP00000009555	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC108230078	cdk5	ENSKMAP00000018376	ENSKMAP00000006034	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.572
LOC108235111	cdk5	ENSKMAP00000022195	ENSKMAP00000006034	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.572
LOC108240515	ENSKMAP00000009644	ENSKMAP00000009555	ENSKMAP00000009644	Uncharacterized protein.	Ras homolog gene family, member Gd.	0.902
LOC108240515	LOC108229538	ENSKMAP00000009555	ENSKMAP00000008124	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC108244970	e2f8	ENSKMAP00000028064	ENSKMAP00000027402	E2F transcription factor 7.	E2F transcription factor 8.	0.638
LOC108246957	CDH2	ENSKMAP00000012433	ENSKMAP00000018850	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.901
cdk5	LOC108230078	ENSKMAP00000006034	ENSKMAP00000018376	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.572
cdk5	LOC108235111	ENSKMAP00000006034	ENSKMAP00000022195	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.572
chodl	tmem41b	ENSKMAP00000016085	ENSKMAP00000006498	Chondrolectin.	Transmembrane protein 41B.	0.563
e2f8	LOC108244970	ENSKMAP00000027402	ENSKMAP00000028064	E2F transcription factor 8.	E2F transcription factor 7.	0.638
tmem41b	chodl	ENSKMAP00000006498	ENSKMAP00000016085	Transmembrane protein 41B.	Chondrolectin.	0.563