94 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108231213	Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
	tp53i13	Uncharacterized protein. (606 aa)
	ino80	INO80 complex ATPase subunit. (1474 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1105 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
	LOC108241482	CREB binding protein a. (2490 aa)
	ube2b	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
	ube2a	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	ddb2	Damage-specific DNA binding protein 2. (497 aa)
	ercc6	Excision repair cross-complementation group 6. (1442 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (284 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	cunh10orf90	ALMS_motif domain-containing protein. (193 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (685 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	cops9	COP9 signalosome subunit 9. (57 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	LOC108229807	Cullin 4A; Belongs to the cullin family. (746 aa)
	ercc5	Excision repair cross-complementation group 5. (1028 aa)
	LOC108232381	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (748 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa)
	sprtn	SprT-like N-terminal domain. (569 aa)
	men1	Multiple endocrine neoplasia I. (628 aa)
	LOC108249775	Opsin 5; Belongs to the G-protein coupled receptor 1 family. (317 aa)
	LOC108250440	E1A binding protein p300 a. (2399 aa)
	sirt6	Sirtuin 6. (350 aa)
	LOC108244594	Mitogen-activated protein kinase. (359 aa)
	LOC108233159	Mitogen-activated protein kinase. (364 aa)
	uvssa	UV-stimulated scaffold protein A. (762 aa)
	sirt1	Sirtuin 1. (693 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (320 aa)
	brca2	BRCA2 DNA repair associated. (2641 aa)
	polk	Polymerase (DNA directed) kappa. (401 aa)
	ube4b	Ubiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1379 aa)
	trim32	Tripartite motif containing 32. (682 aa)
	opn3	Opsin 3. (385 aa)
	LOC108238001	High mobility group nucleosome binding domain 6. (94 aa)
	LOC108250746	Fibrinogen C-terminal domain-containing protein. (235 aa)
	bivm	Basic, immunoglobulin-like variable motif containing. (481 aa)
	ep300	E1A binding protein p300 b. (2785 aa)
	bmf	Uncharacterized protein. (163 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (869 aa)
	actr5	Actin related protein 5; Belongs to the actin family. (642 aa)
	LOC108237852	Zgc:153993. (205 aa)
	bcl2	BCL2 apoptosis regulator b. (297 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (984 aa)
	ENSKMAP00000018367	Uncharacterized protein. (181 aa)
	LOC108247643	CREB binding protein b. (2428 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1544 aa)
	primpol	Primase and polymerase (DNA-directed). (492 aa)
	ENSKMAP00000001053	Uncharacterized protein. (109 aa)
	LOC108229311	Uncharacterized protein. (209 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
	rev1	REV1 DNA directed polymerase. (1363 aa)
	ENSKMAP00000002335	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (336 aa)
	ENSKMAP00000002747	Fibrinogen C-terminal domain-containing protein. (129 aa)
	ddb1	Damage-specific DNA binding protein 1. (1075 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (935 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (458 aa)
	LOC108241711	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
	LOC108241647	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	impact	Impact RWD domain protein. (319 aa)
	ro60	Ro60, Y RNA binding protein. (537 aa)
	tmem161a	Transmembrane protein 161A. (497 aa)
	rhbdd1	Rhomboid domain containing 1. (327 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
	rhno1	Si:ch73-352p4.5. (290 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (787 aa)
	dcun1d3	DCN1-like protein. (326 aa)
	pold1	DNA polymerase. (1105 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (837 aa)
	mc1r	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (310 aa)
	ppid	Peptidylprolyl isomerase D. (372 aa)
	MFAP4	Microfibril associated protein 4. (232 aa)
	ENSKMAP00000012064	Fibrinogen C-terminal domain-containing protein. (234 aa)
	LOC108246862	Mitogen-activated protein kinase. (356 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	LOC108247482	Fibrinogen C-terminal domain-containing protein. (311 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
	usf1	Upstream transcription factor 1. (299 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (621 aa)
	nfatc4	Nuclear factor of activated T cells 4. (830 aa)
	pclaf	PCNA clamp associated factor. (116 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1590 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	polh	Polymerase (DNA directed), eta. (738 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	eif2s1	ENSKMAP00000000569	ENSKMAP00000025510	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.950
EIF2AK4	impact	ENSKMAP00000000569	ENSKMAP00000006046	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.480
EIF2AK4	sirt1	ENSKMAP00000000569	ENSKMAP00000011175	Eukaryotic translation initiation factor 2 alpha kinase 4.	Sirtuin 1.	0.423
ENSKMAP00000001053	LOC108232381	ENSKMAP00000001053	ENSKMAP00000029821	Uncharacterized protein.	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	0.520
ENSKMAP00000001053	bivm	ENSKMAP00000001053	ENSKMAP00000020665	Uncharacterized protein.	Basic, immunoglobulin-like variable motif containing.	0.786
ENSKMAP00000001053	brca2	ENSKMAP00000001053	ENSKMAP00000010397	Uncharacterized protein.	BRCA2 DNA repair associated.	0.605
ENSKMAP00000001053	chek1	ENSKMAP00000001053	ENSKMAP00000030103	Uncharacterized protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.999
ENSKMAP00000001053	ercc1	ENSKMAP00000001053	ENSKMAP00000027419	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.748
ENSKMAP00000001053	ercc2	ENSKMAP00000001053	ENSKMAP00000028774	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.812
ENSKMAP00000001053	ercc4	ENSKMAP00000001053	ENSKMAP00000029520	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.811
ENSKMAP00000001053	ercc5	ENSKMAP00000001053	ENSKMAP00000029766	Uncharacterized protein.	Excision repair cross-complementation group 5.	0.786
ENSKMAP00000001053	ercc6	ENSKMAP00000001053	ENSKMAP00000027213	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.559
ENSKMAP00000001053	msh2	ENSKMAP00000001053	ENSKMAP00000015699	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.757
ENSKMAP00000001053	msh6	ENSKMAP00000001053	ENSKMAP00000022133	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.828
ENSKMAP00000001053	pold1	ENSKMAP00000001053	ENSKMAP00000013397	Uncharacterized protein.	DNA polymerase.	0.479
ENSKMAP00000001053	rev1	ENSKMAP00000001053	ENSKMAP00000001976	Uncharacterized protein.	REV1 DNA directed polymerase.	0.554
ENSKMAP00000001053	rhno1	ENSKMAP00000001053	ENSKMAP00000015648	Uncharacterized protein.	Si:ch73-352p4.5.	0.648
ENSKMAP00000001053	ube2a	ENSKMAP00000001053	ENSKMAP00000027199	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.520
ENSKMAP00000001053	ube2b	ENSKMAP00000001053	ENSKMAP00000026630	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.520
ENSKMAP00000001053	xpa	ENSKMAP00000001053	ENSKMAP00000028000	Uncharacterized protein.	Xeroderma pigmentosum, complementation group A.	0.566