54 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	nfrkb	Nuclear factor related to kappaB binding protein. (1278 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1590 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1179 aa)
	cct3	T-complex protein 1 subunit gamma. (540 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1037 aa)
	LOC108241600	Homeobox containing 1a. (347 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	ENSKMAP00000001053	Uncharacterized protein. (109 aa)
	Atm	Uncharacterized protein. (130 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	ENSKMAP00000000467	TAN domain-containing protein. (123 aa)
	smg6	SMG6 nonsense mediated mRNA decay factor. (1636 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	smg5	SMG5 nonsense mediated mRNA decay factor. (1124 aa)
	exosc10	Exosome component 10. (886 aa)
	ENSKMAP00000021613	Decapping mRNA 2. (319 aa)
	ino80d	INO80 complex subunit Da. (1000 aa)
	mcrs1	Microspherule protein 1. (466 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (802 aa)
	Nek2	NIMA-related kinase 2. (492 aa)
	terf2	HTH myb-type domain-containing protein. (603 aa)
	ino80	INO80 complex ATPase subunit. (1474 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1105 aa)
	ccdc174	Coiled-coil domain containing 174. (535 aa)
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	ylpm1	YLP motif containing 1. (2110 aa)
	fbxo4	F-box protein 4. (395 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (364 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	LOC108245905	TERF1 (TRF1)-interacting nuclear factor 2. (570 aa)
	LOC108232644	Poly [ADP-ribose] polymerase. (1288 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
	ten1	TEN1 subunit of CST complex. (135 aa)
	LOC108234987	Poly [ADP-ribose] polymerase. (1267 aa)
	ENSKMAP00000013709	Uncharacterized protein. (437 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	ino80e	INO80 complex subunit E. (250 aa)
	smg1	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (2520 aa)
	dkc1	Dyskeratosis congenita 1, dyskerin. (497 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (536 aa)
	terf1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (366 aa)
	sirt6	Sirtuin 6. (350 aa)
	ENSKMAP00000008727	Uncharacterized protein. (170 aa)
	atrx	ATRX chromatin remodeler. (2228 aa)
	pot1	Protection of telomeres 1 homolog. (770 aa)
	LOC108247429	Uncharacterized protein. (1905 aa)
	LOC108242278	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa)
	naf1	Uncharacterized protein. (486 aa)
	tfpt	TCF3 (E2A) fusion partner. (197 aa)
	gnl3l	Guanine nucleotide binding protein-like 3 (nucleolar)-like. (563 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (590 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSKMAP00000000467	ENSKMAP00000000507	ENSKMAP00000000467	Uncharacterized protein.	TAN domain-containing protein.	0.926
Atm	ENSKMAP00000001053	ENSKMAP00000000507	ENSKMAP00000001053	Uncharacterized protein.	Uncharacterized protein.	0.996
Atm	ENSKMAP00000008727	ENSKMAP00000000507	ENSKMAP00000008727	Uncharacterized protein.	Uncharacterized protein.	0.558
Atm	LOC108242278	ENSKMAP00000000507	ENSKMAP00000007581	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.626
Atm	LOC108247429	ENSKMAP00000000507	ENSKMAP00000007790	Uncharacterized protein.	Uncharacterized protein.	0.401
Atm	atrx	ENSKMAP00000000507	ENSKMAP00000008603	Uncharacterized protein.	ATRX chromatin remodeler.	0.401
Atm	ercc1	ENSKMAP00000000507	ENSKMAP00000027419	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.594
Atm	ercc4	ENSKMAP00000000507	ENSKMAP00000029520	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.595
Atm	rad50	ENSKMAP00000000507	ENSKMAP00000012919	Uncharacterized protein.	RAD50 homolog, double strand break repair protein.	0.994
Atm	rtel1	ENSKMAP00000000507	ENSKMAP00000003058	Uncharacterized protein.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.691
Atm	slx4	ENSKMAP00000000507	ENSKMAP00000026597	Uncharacterized protein.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.613
Atm	smg1	ENSKMAP00000000507	ENSKMAP00000011077	Uncharacterized protein.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.558
Atm	terf1	ENSKMAP00000000507	ENSKMAP00000009379	Uncharacterized protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.535
Atm	uchl5	ENSKMAP00000000507	ENSKMAP00000016234	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.406
Atm	xrcc1	ENSKMAP00000000507	ENSKMAP00000026769	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.408
Atm	xrcc5	ENSKMAP00000000507	ENSKMAP00000015947	Uncharacterized protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.891
ENSKMAP00000000467	Atm	ENSKMAP00000000467	ENSKMAP00000000507	TAN domain-containing protein.	Uncharacterized protein.	0.926
ENSKMAP00000000467	ENSKMAP00000001053	ENSKMAP00000000467	ENSKMAP00000001053	TAN domain-containing protein.	Uncharacterized protein.	0.970
ENSKMAP00000000467	ENSKMAP00000008727	ENSKMAP00000000467	ENSKMAP00000008727	TAN domain-containing protein.	Uncharacterized protein.	0.558
ENSKMAP00000000467	LOC108242278	ENSKMAP00000000467	ENSKMAP00000007581	TAN domain-containing protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.626