STRINGSTRING
tpr tpr riok2 riok2 cdc26 cdc26 rb1 rb1 anapc4 anapc4 pinx1 pinx1 klhl22 klhl22 cenpv cenpv actr5 actr5 LOC108228258 LOC108228258 uchl5 uchl5 LOC108245905 LOC108245905 anapc5 anapc5 xrcc5 xrcc5 LOC108248224 LOC108248224 LOC108248232 LOC108248232 ten1 ten1 ENSKMAP00000014373 ENSKMAP00000014373 LOC108234987 LOC108234987 LOC108247550 LOC108247550 ENSKMAP00000013709 ENSKMAP00000013709 rad50 rad50 LOC108239511 LOC108239511 ino80e ino80e mad1l1 mad1l1 LOC108229738 LOC108229738 gen1 gen1 ENSKMAP00000011592 ENSKMAP00000011592 smg1 smg1 dkc1 dkc1 spdl1 spdl1 LOC108244642 LOC108244642 cct2 cct2 bcl7a bcl7a anapc7 anapc7 ncapd2 ncapd2 lcmt1 lcmt1 smc5 smc5 terf1 terf1 sirt6 sirt6 ncaph ncaph ENSKMAP00000008727 ENSKMAP00000008727 atrx atrx pot1 pot1 LOC108229553 LOC108229553 mapk15 mapk15 mnat1 mnat1 LOC108247429 LOC108247429 LOC108242278 LOC108242278 ino80c ino80c naf1 naf1 kat2b kat2b LOC108244717 LOC108244717 tfpt tfpt slf1 slf1 cdc16 cdc16 nek7 nek7 cdc6 cdc6 anapc2 anapc2 ppp1r10 ppp1r10 LOC108251554 LOC108251554 ttk ttk rtel1 rtel1 trappc12 trappc12 wapl wapl LOC108240497 LOC108240497 xrcc3 xrcc3 cct3 cct3 nat10 nat10 LOC108250252 LOC108250252 setdb1 setdb1 lig4 lig4 LOC108245429 LOC108245429 LOC108241600 LOC108241600 mapkapk5 mapkapk5 ENSKMAP00000001053 ENSKMAP00000001053 Atm Atm map2k7 map2k7 ENSKMAP00000000467 ENSKMAP00000000467 Mos Mos smg6 smg6 haspin haspin ncapg ncapg mad2l1 mad2l1 ino80d ino80d mcrs1 mcrs1 anapc1 anapc1 LOC108235257 LOC108235257 dnmt1 dnmt1 map3k4 map3k4 cdc23 cdc23 Nek2 Nek2 cdc27 cdc27 rnf4 rnf4 zw10 zw10 tasor tasor Cdca5 Cdca5 terf2 terf2 mcph1 mcph1 LOC108231213 LOC108231213 kntc1 kntc1 rmi2 rmi2 ino80 ino80 LOC108239236 LOC108239236 dhx36 dhx36 zwilch zwilch ccdc174 ccdc174 slx4 slx4 cenpe cenpe xrcc1 xrcc1 LOC108244389 LOC108244389 LOC108231347 LOC108231347 smc4 smc4 ercc1 ercc1 AXIN2 AXIN2 ndc80 ndc80 CUL3 CUL3 gnl3l gnl3l bub1 bub1 nsmce2 nsmce2 fbxo42 fbxo42 atf7ip atf7ip pnkp pnkp ercc4 ercc4 smc2 smc2 actl6a actl6a nfrkb nfrkb ENSKMAP00000021613 ENSKMAP00000021613 LOC108231940 LOC108231940 LOC108242521 LOC108242521 exosc10 exosc10 bub1b bub1b anapc15 anapc15 mad2l1bp mad2l1bp morc2 morc2 smg5 smg5 ube2c ube2c cct5 cct5 cdt1 cdt1 LOC108232644 LOC108232644 mcm2 mcm2 ylpm1 ylpm1 bub3 bub3 mphosph8 mphosph8 fbxo4 fbxo4 znf207 znf207
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tprTranslocated promoter region b, nuclear basket protein. (2200 aa)
riok2RIO kinase 2 (yeast). (511 aa)
cdc26Cell division cycle 26 homolog. (97 aa)
rb1Retinoblastoma 1. (915 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (799 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (364 aa)
klhl22Kelch-like family member 22. (630 aa)
cenpvCentromere protein V. (206 aa)
actr5Actin related protein 5; Belongs to the actin family. (642 aa)
LOC108228258Uncharacterized protein. (635 aa)
uchl5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
LOC108245905TERF1 (TRF1)-interacting nuclear factor 2. (570 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
LOC108248224Anaphase-promoting complex subunit 11. (84 aa)
LOC108248232APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
ten1TEN1 subunit of CST complex. (135 aa)
ENSKMAP00000014373CDK5 regulatory subunit associated protein 2. (1099 aa)
LOC108234987Poly [ADP-ribose] polymerase. (1267 aa)
LOC108247550Si:ch211-242b18.1. (1719 aa)
ENSKMAP00000013709Uncharacterized protein. (437 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
LOC108239511Translocated promoter region a, nuclear basket protein. (2040 aa)
ino80eINO80 complex subunit E. (250 aa)
mad1l1Mitotic arrest deficient 1 like 1. (722 aa)
LOC108229738SUMO specific peptidase 6a. (394 aa)
gen1Chromo_2 domain-containing protein. (574 aa)
ENSKMAP00000011592Uncharacterized protein. (216 aa)
smg1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (2520 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (497 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
LOC108244642Uncharacterized protein. (1961 aa)
cct2Chaperonin containing TCP1, subunit 2 (beta). (536 aa)
bcl7aBAF chromatin remodeling complex subunit BCL7A. (199 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
ncapd2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1230 aa)
lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
smc5Structural maintenance of chromosomes 5. (1078 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (366 aa)
sirt6Sirtuin 6. (350 aa)
ncaphCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (692 aa)
ENSKMAP00000008727Uncharacterized protein. (170 aa)
atrxATRX chromatin remodeler. (2228 aa)
pot1Protection of telomeres 1 homolog. (770 aa)
LOC108229553Uncharacterized protein. (620 aa)
mapk15Mitogen-activated protein kinase. (559 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
LOC108247429Uncharacterized protein. (1905 aa)
LOC108242278Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa)
ino80cINO80 complex subunit C. (207 aa)
naf1Uncharacterized protein. (486 aa)
kat2bHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
LOC108244717Uncharacterized protein. (1332 aa)
tfptTCF3 (E2A) fusion partner. (197 aa)
slf1SMC5-SMC6 complex localization factor 1. (879 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
nek7NIMA-related kinase 7; Belongs to the protein kinase superfamily. (301 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (575 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (827 aa)
ppp1r10Protein phosphatase 1, regulatory subunit 10. (802 aa)
LOC108251554Si:ch73-290k24.6. (783 aa)
ttkTtk protein kinase. (994 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1179 aa)
trappc12Trafficking protein particle complex 12. (825 aa)
waplWAPL cohesin release factor a. (1187 aa)
LOC108240497CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa)
cct3T-complex protein 1 subunit gamma. (540 aa)
nat10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1037 aa)
LOC108250252WAPL cohesin release factor b. (1220 aa)
setdb1SET domain bifurcated histone lysine methyltransferase 1b. (1267 aa)
lig4DNA ligase. (922 aa)
LOC108245429Uncharacterized protein. (484 aa)
LOC108241600Homeobox containing 1a. (347 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
ENSKMAP00000001053Uncharacterized protein. (109 aa)
AtmUncharacterized protein. (130 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
ENSKMAP00000000467TAN domain-containing protein. (123 aa)
MosV-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily. (245 aa)
smg6SMG6 nonsense mediated mRNA decay factor. (1636 aa)
haspinSi:dkeyp-26a9.2. (1228 aa)
ncapgNon-SMC condensin I complex, subunit G. (1016 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
ino80dINO80 complex subunit Da. (1000 aa)
mcrs1Microspherule protein 1. (466 aa)
anapc1Anaphase promoting complex subunit 1. (1979 aa)
LOC108235257Transcription activation suppressor b. (1835 aa)
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1507 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1590 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
Nek2NIMA-related kinase 2. (492 aa)
cdc27Cell division cycle 27. (803 aa)
rnf4RING-type domain-containing protein. (198 aa)
zw10Zw10 kinetochore protein. (766 aa)
tasorDUF3715 domain-containing protein. (2043 aa)
Cdca5Cell division cycle associated 5. (265 aa)
terf2HTH myb-type domain-containing protein. (603 aa)
mcph1Microcephalin 1. (817 aa)
LOC108231213Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
kntc1Kinetochore associated 1. (2124 aa)
rmi2RecQ mediated genome instability 2. (145 aa)
ino80INO80 complex ATPase subunit. (1474 aa)
LOC108239236Axin 2 (conductin, axil). (840 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1105 aa)
zwilchZwilch kinetochore protein. (586 aa)
ccdc174Coiled-coil domain containing 174. (535 aa)
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa)
cenpeKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1672 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa)
LOC108244389SET domain and mariner transposase fusion gene. (287 aa)
LOC108231347Uncharacterized protein. (191 aa)
smc4Structural maintenance of chromosomes protein. (1255 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
AXIN2Axin 2. (784 aa)
ndc80NDC80 kinetochore complex component. (640 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
gnl3lGuanine nucleotide binding protein-like 3 (nucleolar)-like. (563 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1154 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (228 aa)
fbxo42F-box protein 42. (732 aa)
atf7ipActivating transcription factor 7 interacting protein. (971 aa)
pnkpPolynucleotide kinase 3'-phosphatase. (590 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
smc2Structural maintenance of chromosomes protein. (1200 aa)
actl6aActin-like 6A; Belongs to the actin family. (429 aa)
nfrkbNuclear factor related to kappaB binding protein. (1278 aa)
ENSKMAP00000021613Decapping mRNA 2. (319 aa)
LOC108231940Uncharacterized protein. (265 aa)
LOC108242521NIMA-related kinase 6; Belongs to the protein kinase superfamily. (306 aa)
exosc10Exosome component 10. (886 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (428 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
mad2l1bpMAD2L1 binding protein. (386 aa)
morc2MORC family CW-type zinc finger 2. (1050 aa)
smg5SMG5 nonsense mediated mRNA decay factor. (1124 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (177 aa)
cct5Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
cdt1Chromatin licensing and DNA replication factor 1. (642 aa)
LOC108232644Poly [ADP-ribose] polymerase. (1288 aa)
mcm2DNA helicase; Belongs to the MCM family. (890 aa)
ylpm1YLP motif containing 1. (2110 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
mphosph8Chromo domain-containing protein. (1832 aa)
fbxo4F-box protein 4. (395 aa)
znf207Zinc finger protein 207, b. (473 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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