58 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108241647	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	tmem161a	Transmembrane protein 161A. (497 aa)
	LOC108246862	Mitogen-activated protein kinase. (356 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa)
	LOC108229807	Cullin 4A; Belongs to the cullin family. (746 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	cops9	COP9 signalosome subunit 9. (57 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (685 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (284 aa)
	LOC108241482	CREB binding protein a. (2490 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1105 aa)
	ino80	INO80 complex ATPase subunit. (1474 aa)
	LOC108231213	Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
	polh	Polymerase (DNA directed), eta. (738 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	rhbdd1	Rhomboid domain containing 1. (327 aa)
	nfatc4	Nuclear factor of activated T cells 4. (830 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (748 aa)
	opn3	Opsin 3. (385 aa)
	LOC108250746	Fibrinogen C-terminal domain-containing protein. (235 aa)
	bmf	Uncharacterized protein. (163 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (869 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1544 aa)
	ENSKMAP00000001053	Uncharacterized protein. (109 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
	ENSKMAP00000002335	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (336 aa)
	ENSKMAP00000002747	Fibrinogen C-terminal domain-containing protein. (129 aa)
	ddb1	Damage-specific DNA binding protein 1. (1075 aa)
	ep300	E1A binding protein p300 b. (2785 aa)
	LOC108247643	CREB binding protein b. (2428 aa)
	ENSKMAP00000018367	Uncharacterized protein. (181 aa)
	LOC108237852	Zgc:153993. (205 aa)
	actr5	Actin related protein 5; Belongs to the actin family. (642 aa)
	polk	Polymerase (DNA directed) kappa. (401 aa)
	rhno1	Si:ch73-352p4.5. (290 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	pold1	DNA polymerase. (1105 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (837 aa)
	mc1r	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (310 aa)
	ppid	Peptidylprolyl isomerase D. (372 aa)
	MFAP4	Microfibril associated protein 4. (232 aa)
	ENSKMAP00000012064	Fibrinogen C-terminal domain-containing protein. (234 aa)
	sirt1	Sirtuin 1. (693 aa)
	LOC108233159	Mitogen-activated protein kinase. (364 aa)
	LOC108244594	Mitogen-activated protein kinase. (359 aa)
	LOC108250440	E1A binding protein p300 a. (2399 aa)
	LOC108249775	Opsin 5; Belongs to the G-protein coupled receptor 1 family. (317 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
	LOC108247482	Fibrinogen C-terminal domain-containing protein. (311 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (935 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (458 aa)
	LOC108241711	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
	impact	Impact RWD domain protein. (319 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	eif2s1	ENSKMAP00000000569	ENSKMAP00000025510	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.950
EIF2AK4	impact	ENSKMAP00000000569	ENSKMAP00000006046	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.480
EIF2AK4	sirt1	ENSKMAP00000000569	ENSKMAP00000011175	Eukaryotic translation initiation factor 2 alpha kinase 4.	Sirtuin 1.	0.423
ENSKMAP00000001053	chek1	ENSKMAP00000001053	ENSKMAP00000030103	Uncharacterized protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.999
ENSKMAP00000001053	ercc1	ENSKMAP00000001053	ENSKMAP00000027419	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.748
ENSKMAP00000001053	ercc4	ENSKMAP00000001053	ENSKMAP00000029520	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.811
ENSKMAP00000001053	pold1	ENSKMAP00000001053	ENSKMAP00000013397	Uncharacterized protein.	DNA polymerase.	0.479
ENSKMAP00000001053	rhno1	ENSKMAP00000001053	ENSKMAP00000015648	Uncharacterized protein.	Si:ch73-352p4.5.	0.648
ENSKMAP00000001053	xpa	ENSKMAP00000001053	ENSKMAP00000028000	Uncharacterized protein.	Xeroderma pigmentosum, complementation group A.	0.566
ENSKMAP00000001053	xpc	ENSKMAP00000001053	ENSKMAP00000003546	Uncharacterized protein.	Xeroderma pigmentosum, complementation group C.	0.671
ENSKMAP00000002335	opn3	ENSKMAP00000002335	ENSKMAP00000021465	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.	Opsin 3.	0.487
ENSKMAP00000018367	LOC108237852	ENSKMAP00000018367	ENSKMAP00000017083	Uncharacterized protein.	Zgc:153993.	0.499
LOC108229807	chek1	ENSKMAP00000029593	ENSKMAP00000030103	Cullin 4A; Belongs to the cullin family.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.538
LOC108229807	cul4b	ENSKMAP00000029593	ENSKMAP00000000480	Cullin 4A; Belongs to the cullin family.	Cullin 4B; Belongs to the cullin family.	0.918
LOC108229807	ddb1	ENSKMAP00000029593	ENSKMAP00000003119	Cullin 4A; Belongs to the cullin family.	Damage-specific DNA binding protein 1.	0.978
LOC108229807	ercc1	ENSKMAP00000029593	ENSKMAP00000027419	Cullin 4A; Belongs to the cullin family.	Excision repair cross-complementation group 1.	0.691
LOC108229807	ercc4	ENSKMAP00000029593	ENSKMAP00000029520	Cullin 4A; Belongs to the cullin family.	Excision repair cross-complementation group 4.	0.667
LOC108229807	ino80	ENSKMAP00000029593	ENSKMAP00000026074	Cullin 4A; Belongs to the cullin family.	INO80 complex ATPase subunit.	0.489
LOC108229807	parp1	ENSKMAP00000029593	ENSKMAP00000015581	Cullin 4A; Belongs to the cullin family.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.579
LOC108229807	pold1	ENSKMAP00000029593	ENSKMAP00000013397	Cullin 4A; Belongs to the cullin family.	DNA polymerase.	0.617