(59 nodes) Tissue regeneration network (Kryptolebias marmoratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	klf5	Progesterone immunomodulatory binding factor 1. (492 aa)
	LOC108249081	SIX homeobox 7. (261 aa)
	tmem182	Transmembrane protein 182a. (239 aa)
	lmo2	LIM domain only 2 (rhombotin-like 1). (160 aa)
	LOC108233160	Interferon-related developmental regulator 2. (454 aa)
	LOC108247379	Ninjurin 1. (149 aa)
	ttk	Ttk protein kinase. (994 aa)
	six3	SIX homeobox 3a. (294 aa)
	LOC108232375	Kruppel-like factor 5b. (445 aa)
	LOC108245667	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (388 aa)
	yap1	Yes-associated protein 1. (438 aa)
	larp7	La ribonucleoprotein domain family, member 7. (554 aa)
	LOC108249175	Uncharacterized protein. (160 aa)
	ENSKMAP00000006836	Si:dkey-83h2.3. (211 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	six6	SIX homeobox 6a. (245 aa)
	bin3	Bridging integrator 3. (253 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	LOC108246957	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (913 aa)
	tm4sf4	Transmembrane 4 L six family member 4. (203 aa)
	LOC108241749	Uncharacterized protein. (883 aa)
	CD9	Tetraspanin. (228 aa)
	LOC108246926	SIX homeobox 3b. (277 aa)
	ptn	Pleiotrophin. (169 aa)
	LOC108237907	Retinoblastoma binding protein 4, like. (440 aa)
	LOC108232625	POU domain protein. (497 aa)
	ptgfrn	Si:ch211-132g1.7. (882 aa)
	ascl1	Achaete-scute family bHLH transcription factor 1a. (206 aa)
	LOC108243621	Kruppel-like factor 5 like. (451 aa)
	fam53b	Family with sequence similarity 53 member B. (409 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (807 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
	LOC108235105	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (401 aa)
	LOC108235048	Ninjurin 2. (160 aa)
	ninj1	Uncharacterized protein. (147 aa)
	gata3	GATA binding protein 3. (441 aa)
	LOC108232401	Retinoblastoma binding protein 4. (424 aa)
	LOC108230118	Tetraspanin. (234 aa)
	LOC108250076	Si:dkey-49n23.1; Belongs to the semaphorin family. (780 aa)
	LOC108237950	Uncharacterized protein. (249 aa)
	gdf11	Growth differentiation factor 11. (397 aa)
	LOC108242552	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	LOC108230888	T-box transcription factor 5a. (519 aa)
	ezh2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (759 aa)
	CPQ	Carboxypeptidase Q. (487 aa)
	LOC108246120	Beta-1,3-N-acetylglucosaminyltransferase. (378 aa)
	CCN3	Cellular communication network factor 3. (346 aa)
	akirin1	Akirin 1. (187 aa)
	axin1	Axin 1. (848 aa)
	LOC108230380	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (183 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (765 aa)
	LOC108235134	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	fgfr1	Fibroblast growth factor receptor. (831 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (928 aa)
	esco2	Establishment of sister chromatid cohesion N-acetyltransferase 2. (625 aa)
	FAM53B	Family with sequence similarity 53 member B. (451 aa)
	LOC108244439	Growth associated protein 43. (245 aa)
	ifrd1	Interferon-related developmental regulator 1. (428 aa)
	LOC108232846	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD9	ptgfrn	ENSKMAP00000012930	ENSKMAP00000017084	Tetraspanin.	Si:ch211-132g1.7.	0.810
CDH2	LOC108245667	ENSKMAP00000018850	ENSKMAP00000005148	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.550
CDH2	LOC108246957	ENSKMAP00000018850	ENSKMAP00000012433	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
EZH1	LOC108232401	ENSKMAP00000026223	ENSKMAP00000019969	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	Retinoblastoma binding protein 4.	0.925
EZH1	LOC108237907	ENSKMAP00000026223	ENSKMAP00000016066	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	Retinoblastoma binding protein 4, like.	0.924
LOC108230118	ptgfrn	ENSKMAP00000020027	ENSKMAP00000017084	Tetraspanin.	Si:ch211-132g1.7.	0.810
LOC108230888	yap1	ENSKMAP00000023692	ENSKMAP00000005198	T-box transcription factor 5a.	Yes-associated protein 1.	0.722
LOC108232401	EZH1	ENSKMAP00000019969	ENSKMAP00000026223	Retinoblastoma binding protein 4.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.925
LOC108232401	ezh2	ENSKMAP00000019969	ENSKMAP00000024022	Retinoblastoma binding protein 4.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.924
LOC108235048	LOC108244439	ENSKMAP00000019565	ENSKMAP00000028992	Ninjurin 2.	Growth associated protein 43.	0.408
LOC108235048	ptn	ENSKMAP00000019565	ENSKMAP00000015534	Ninjurin 2.	Pleiotrophin.	0.664
LOC108235105	wnt4	ENSKMAP00000019094	ENSKMAP00000007346	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.605
LOC108235134	wnt4	ENSKMAP00000026275	ENSKMAP00000007346	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.605
LOC108237907	EZH1	ENSKMAP00000016066	ENSKMAP00000026223	Retinoblastoma binding protein 4, like.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.924
LOC108237907	ezh2	ENSKMAP00000016066	ENSKMAP00000024022	Retinoblastoma binding protein 4, like.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.924
LOC108241749	LOC108242552	ENSKMAP00000012763	ENSKMAP00000023653	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.534
LOC108242552	LOC108241749	ENSKMAP00000023653	ENSKMAP00000012763	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.534
LOC108242552	axin1	ENSKMAP00000023653	ENSKMAP00000026038	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin 1.	0.534
LOC108244439	LOC108235048	ENSKMAP00000028992	ENSKMAP00000019565	Growth associated protein 43.	Ninjurin 2.	0.408
LOC108245667	CDH2	ENSKMAP00000005148	ENSKMAP00000018850	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.550