(29 nodes) Regulation of protein import into nucleus network (Kryptolebias marmoratus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ect2	Epithelial cell transforming 2. (1050 aa)
	NUP54	Nucleoporin 54. (623 aa)
	tpr	Translocated promoter region b, nuclear basket protein. (2200 aa)
	LOC108229830	Uncharacterized protein. (166 aa)
	pkig	Protein kinase (cAMP-dependent, catalytic) inhibitor gamma. (78 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (619 aa)
	nf1	Neurofibromin 1b. (2727 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (818 aa)
	chp1	Calcineurin-like EF-hand protein 1. (195 aa)
	LOC108233996	Nucleolar and coiled-body phosphoprotein 1. (927 aa)
	zpr1	ZPR1 zinc finger. (446 aa)
	rab23	RAB23, member RAS oncogene family. (235 aa)
	LOC108230380	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (183 aa)
	LOC108236365	Junction plakoglobin a. (725 aa)
	nkd1	NKD inhibitor of WNT signaling pathway 1. (447 aa)
	LOC108232846	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	dmap1	DNA methyltransferase 1 associated protein 1. (483 aa)
	ptpn5	Protein tyrosine phosphatase non-receptor type 5. (573 aa)
	LOC108228646	Si:dkey-206d17.12. (261 aa)
	LOC108241578	Calcineurin-like EF-hand protein 2. (194 aa)
	nup58	Nucleoporin 58. (590 aa)
	sirt6	Sirtuin 6. (350 aa)
	bag3	BCL2 associated athanogene 3. (499 aa)
	LOC108228916	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	LOC108239511	Translocated promoter region a, nuclear basket protein. (2040 aa)
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	efcab7	EF-hand calcium binding domain 7. (609 aa)
	ipo5	Karyopherin (importin) beta 3. (1093 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2742 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108239511	NUP54	ENSKMAP00000012648	ENSKMAP00000017428	Translocated promoter region a, nuclear basket protein.	Nucleoporin 54.	0.791
LOC108239511	nup58	ENSKMAP00000012648	ENSKMAP00000007511	Translocated promoter region a, nuclear basket protein.	Nucleoporin 58.	0.683
NUP54	LOC108239511	ENSKMAP00000017428	ENSKMAP00000012648	Nucleoporin 54.	Translocated promoter region a, nuclear basket protein.	0.791
NUP54	ipo5	ENSKMAP00000017428	ENSKMAP00000016407	Nucleoporin 54.	Karyopherin (importin) beta 3.	0.779
NUP54	nup58	ENSKMAP00000017428	ENSKMAP00000007511	Nucleoporin 54.	Nucleoporin 58.	0.996
NUP54	tpr	ENSKMAP00000017428	ENSKMAP00000017840	Nucleoporin 54.	Translocated promoter region b, nuclear basket protein.	0.791
ipo5	NUP54	ENSKMAP00000016407	ENSKMAP00000017428	Karyopherin (importin) beta 3.	Nucleoporin 54.	0.779
ipo5	nup58	ENSKMAP00000016407	ENSKMAP00000007511	Karyopherin (importin) beta 3.	Nucleoporin 58.	0.521
nup58	LOC108239511	ENSKMAP00000007511	ENSKMAP00000012648	Nucleoporin 58.	Translocated promoter region a, nuclear basket protein.	0.683
nup58	NUP54	ENSKMAP00000007511	ENSKMAP00000017428	Nucleoporin 58.	Nucleoporin 54.	0.996
nup58	ipo5	ENSKMAP00000007511	ENSKMAP00000016407	Nucleoporin 58.	Karyopherin (importin) beta 3.	0.521
nup58	tpr	ENSKMAP00000007511	ENSKMAP00000017840	Nucleoporin 58.	Translocated promoter region b, nuclear basket protein.	0.683
rab23	smo	ENSKMAP00000024662	ENSKMAP00000020439	RAB23, member RAS oncogene family.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.615
smo	rab23	ENSKMAP00000020439	ENSKMAP00000024662	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	RAB23, member RAS oncogene family.	0.615
tpr	NUP54	ENSKMAP00000017840	ENSKMAP00000017428	Translocated promoter region b, nuclear basket protein.	Nucleoporin 54.	0.791
tpr	nup58	ENSKMAP00000017840	ENSKMAP00000007511	Translocated promoter region b, nuclear basket protein.	Nucleoporin 58.	0.683