node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPA1 | pot1 | ENSKMAP00000000242 | ENSKMAP00000008433 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Protection of telomeres 1 homolog. | 0.560 |
RPA1 | rad50 | ENSKMAP00000000242 | ENSKMAP00000012919 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | RAD50 homolog, double strand break repair protein. | 0.795 |
RPA1 | rpa1 | ENSKMAP00000000242 | ENSKMAP00000007505 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.901 |
RPA1 | stn1 | ENSKMAP00000000242 | ENSKMAP00000028897 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | STN1 subunit of CST complex. | 0.879 |
RPA1 | terf1 | ENSKMAP00000000242 | ENSKMAP00000009379 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. | 0.486 |
pot1 | RPA1 | ENSKMAP00000008433 | ENSKMAP00000000242 | Protection of telomeres 1 homolog. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.560 |
pot1 | rad50 | ENSKMAP00000008433 | ENSKMAP00000012919 | Protection of telomeres 1 homolog. | RAD50 homolog, double strand break repair protein. | 0.564 |
pot1 | rpa1 | ENSKMAP00000008433 | ENSKMAP00000007505 | Protection of telomeres 1 homolog. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.560 |
pot1 | stn1 | ENSKMAP00000008433 | ENSKMAP00000028897 | Protection of telomeres 1 homolog. | STN1 subunit of CST complex. | 0.758 |
pot1 | terf1 | ENSKMAP00000008433 | ENSKMAP00000009379 | Protection of telomeres 1 homolog. | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. | 0.964 |
pot1 | terf2 | ENSKMAP00000008433 | ENSKMAP00000025205 | Protection of telomeres 1 homolog. | HTH myb-type domain-containing protein. | 0.965 |
rad50 | RPA1 | ENSKMAP00000012919 | ENSKMAP00000000242 | RAD50 homolog, double strand break repair protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.795 |
rad50 | pot1 | ENSKMAP00000012919 | ENSKMAP00000008433 | RAD50 homolog, double strand break repair protein. | Protection of telomeres 1 homolog. | 0.564 |
rad50 | rpa1 | ENSKMAP00000012919 | ENSKMAP00000007505 | RAD50 homolog, double strand break repair protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.795 |
rad50 | stn1 | ENSKMAP00000012919 | ENSKMAP00000028897 | RAD50 homolog, double strand break repair protein. | STN1 subunit of CST complex. | 0.462 |
rad50 | terf1 | ENSKMAP00000012919 | ENSKMAP00000009379 | RAD50 homolog, double strand break repair protein. | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. | 0.601 |
rad50 | terf2 | ENSKMAP00000012919 | ENSKMAP00000025205 | RAD50 homolog, double strand break repair protein. | HTH myb-type domain-containing protein. | 0.766 |
rpa1 | RPA1 | ENSKMAP00000007505 | ENSKMAP00000000242 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.901 |
rpa1 | pot1 | ENSKMAP00000007505 | ENSKMAP00000008433 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Protection of telomeres 1 homolog. | 0.560 |
rpa1 | rad50 | ENSKMAP00000007505 | ENSKMAP00000012919 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | RAD50 homolog, double strand break repair protein. | 0.795 |