node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSKMAP00000004758 | LOC108233917 | ENSKMAP00000004758 | ENSKMAP00000014916 | MGS domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.984 |
ENSKMAP00000004758 | LOC108245652 | ENSKMAP00000004758 | ENSKMAP00000003626 | MGS domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.984 |
ENSKMAP00000004758 | adsl | ENSKMAP00000004758 | ENSKMAP00000022216 | MGS domain-containing protein. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
ENSKMAP00000004758 | adss1 | ENSKMAP00000004758 | ENSKMAP00000020925 | MGS domain-containing protein. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.984 |
ENSKMAP00000004758 | atic | ENSKMAP00000004758 | ENSKMAP00000015582 | MGS domain-containing protein. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.989 |
ENSKMAP00000004758 | gart | ENSKMAP00000004758 | ENSKMAP00000001257 | MGS domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
ENSKMAP00000004758 | pfas | ENSKMAP00000004758 | ENSKMAP00000010409 | MGS domain-containing protein. | Phosphoribosylformylglycinamidine synthase. | 0.407 |
ENSKMAP00000004758 | ppat | ENSKMAP00000004758 | ENSKMAP00000006674 | MGS domain-containing protein. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.966 |
LOC108233917 | ENSKMAP00000004758 | ENSKMAP00000014916 | ENSKMAP00000004758 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | MGS domain-containing protein. | 0.984 |
LOC108233917 | LOC108245652 | ENSKMAP00000014916 | ENSKMAP00000003626 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
LOC108233917 | adsl | ENSKMAP00000014916 | ENSKMAP00000022216 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |
LOC108233917 | adss1 | ENSKMAP00000014916 | ENSKMAP00000020925 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
LOC108233917 | atic | ENSKMAP00000014916 | ENSKMAP00000015582 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.984 |
LOC108233917 | gart | ENSKMAP00000014916 | ENSKMAP00000001257 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.975 |
LOC108233917 | ppat | ENSKMAP00000014916 | ENSKMAP00000006674 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.675 |
LOC108245652 | ENSKMAP00000004758 | ENSKMAP00000003626 | ENSKMAP00000004758 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | MGS domain-containing protein. | 0.984 |
LOC108245652 | LOC108233917 | ENSKMAP00000003626 | ENSKMAP00000014916 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
LOC108245652 | adsl | ENSKMAP00000003626 | ENSKMAP00000022216 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |
LOC108245652 | adss1 | ENSKMAP00000003626 | ENSKMAP00000020925 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.932 |
LOC108245652 | atic | ENSKMAP00000003626 | ENSKMAP00000015582 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.984 |