(46 nodes) Positive regulation of endocytosis network (Kryptolebias marmoratus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fmr1	Fragile X mental retardation 1. (517 aa)
	LOC108231808	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (170 aa)
	GREM1	Gremlin; Belongs to the DAN family. (172 aa)
	clul1	Clusterin; Belongs to the clusterin family. (461 aa)
	LOC108238721	Low density lipoprotein receptor adaptor protein 1a. (300 aa)
	ptpn5	Protein tyrosine phosphatase non-receptor type 5. (573 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	LOC108239997	Zgc:123278. (184 aa)
	LOC108229363	Battenin. (216 aa)
	ENSKMAP00000004905	Battenin. (141 aa)
	LOC108244547	C-C motif chemokine. (109 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (654 aa)
	ENSKMAP00000005920	Uncharacterized protein. (132 aa)
	LOC108248645	Cell division cycle 42. (191 aa)
	LOC108250392	Apolipoprotein Ea. (251 aa)
	LOC108239949	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1340 aa)
	cd63	Tetraspanin. (240 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	LOC108238902	Vitronectin b. (439 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	CDC42	Cell division cycle 42. (197 aa)
	LOC108235453	Uncharacterized protein. (197 aa)
	LOC108235454	Uncharacterized protein. (190 aa)
	scyl2	SCY1 like pseudokinase 2. (918 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (774 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1427 aa)
	ENSKMAP00000016720	Apolipoprotein Eb. (264 aa)
	ano6	Anoctamin. (918 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (313 aa)
	ankfy1	Ankyrin repeat and FYVE domain containing 1. (1166 aa)
	ahi1	Abelson helper integration site 1. (1195 aa)
	gpc3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (524 aa)
	pick1	Protein interacting with prkca 1. (410 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2550 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC108246043	Vitronectin a. (525 aa)
	Dab2	PID domain-containing protein. (137 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (711 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (335 aa)
	LOC108242678	Uncharacterized protein. (204 aa)
	tbc1d5	TBC1 domain family, member 5. (876 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (350 aa)
	LOC108233514	Gremlin 1a, DAN family BMP antagonist. (173 aa)
	clu	Clusterin; Belongs to the clusterin family. (454 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ankfy1	ENSKMAP00000010448	ENSKMAP00000018942	Cell division cycle 42.	Ankyrin repeat and FYVE domain containing 1.	0.473
Dab2	LOC108238721	ENSKMAP00000023865	ENSKMAP00000001559	PID domain-containing protein.	Low density lipoprotein receptor adaptor protein 1a.	0.887
Dab2	ldlrap1	ENSKMAP00000023865	ENSKMAP00000018869	PID domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.911
ENSKMAP00000004905	LOC108229363	ENSKMAP00000004905	ENSKMAP00000003184	Battenin.	Battenin.	0.994
ENSKMAP00000004905	ppt1	ENSKMAP00000004905	ENSKMAP00000025449	Battenin.	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).	0.575
ENSKMAP00000016720	LOC108238721	ENSKMAP00000016720	ENSKMAP00000001559	Apolipoprotein Eb.	Low density lipoprotein receptor adaptor protein 1a.	0.451
ENSKMAP00000016720	LOC108238902	ENSKMAP00000016720	ENSKMAP00000009448	Apolipoprotein Eb.	Vitronectin b.	0.552
ENSKMAP00000016720	LOC108246043	ENSKMAP00000016720	ENSKMAP00000021852	Apolipoprotein Eb.	Vitronectin a.	0.552
ENSKMAP00000016720	clu	ENSKMAP00000016720	ENSKMAP00000029962	Apolipoprotein Eb.	Clusterin; Belongs to the clusterin family.	0.439
ENSKMAP00000016720	clul1	ENSKMAP00000016720	ENSKMAP00000001265	Apolipoprotein Eb.	Clusterin; Belongs to the clusterin family.	0.469
ENSKMAP00000016720	ldlrap1	ENSKMAP00000016720	ENSKMAP00000018869	Apolipoprotein Eb.	Low density lipoprotein receptor adaptor protein 1b.	0.614
GREM1	LOC108233514	ENSKMAP00000000656	ENSKMAP00000029949	Gremlin; Belongs to the DAN family.	Gremlin 1a, DAN family BMP antagonist.	0.902
LOC108229363	ENSKMAP00000004905	ENSKMAP00000003184	ENSKMAP00000004905	Battenin.	Battenin.	0.994
LOC108229363	ppt1	ENSKMAP00000003184	ENSKMAP00000025449	Battenin.	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).	0.575
LOC108231808	vegfa	ENSKMAP00000000325	ENSKMAP00000020088	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.902
LOC108233514	GREM1	ENSKMAP00000029949	ENSKMAP00000000656	Gremlin 1a, DAN family BMP antagonist.	Gremlin; Belongs to the DAN family.	0.902
LOC108235453	ankfy1	ENSKMAP00000010716	ENSKMAP00000018942	Uncharacterized protein.	Ankyrin repeat and FYVE domain containing 1.	0.465
LOC108235454	ankfy1	ENSKMAP00000010757	ENSKMAP00000018942	Uncharacterized protein.	Ankyrin repeat and FYVE domain containing 1.	0.465
LOC108238721	Dab2	ENSKMAP00000001559	ENSKMAP00000023865	Low density lipoprotein receptor adaptor protein 1a.	PID domain-containing protein.	0.887
LOC108238721	ENSKMAP00000016720	ENSKMAP00000001559	ENSKMAP00000016720	Low density lipoprotein receptor adaptor protein 1a.	Apolipoprotein Eb.	0.451