(44 nodes) Axon extension network (Kryptolebias marmoratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	slit2	Slit homolog 2 (Drosophila). (1582 aa)
	ENSKMAP00000000874	Thrombospondin, type I, domain containing 7Aa. (1197 aa)
	ENSKMAP00000001478	Si:dkey-33o22.1. (88 aa)
	myo9a	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2462 aa)
	LOC108243308	Uncharacterized protein; Belongs to the semaphorin family. (623 aa)
	LOC108238867	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a. (1288 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1033 aa)
	mycbp2	MYC binding protein 2. (4580 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (426 aa)
	LOC108249163	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (469 aa)
	sema5b	Sema domain-containing protein. (1103 aa)
	LOC108236984	Doublecortin-like kinase 1a. (721 aa)
	LOC108250397	Endothelin 1. (163 aa)
	LOC108247446	Slit homolog 1b (Drosophila). (1427 aa)
	LOC108230473	Sema domain-containing protein. (1078 aa)
	LOC108231368	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	c9orf72	Zgc:100846. (462 aa)
	LOC108236452	Survival of motor neuron 1, telomeric. (282 aa)
	LOC108235970	Doublecortin-like kinase 1b. (751 aa)
	spast	Spastin; Belongs to the AAA ATPase family. (529 aa)
	ssna1	Sjogren syndrome nuclear autoantigen 1. (114 aa)
	srf	Serum response factor b. (596 aa)
	dcx	Uncharacterized protein. (379 aa)
	spg11	SPG11 vesicle trafficking associated, spatacsin. (2262 aa)
	LOC108251136	MADS-box domain-containing protein. (494 aa)
	LOC108236657	Slit homolog 3 (Drosophila). (1538 aa)
	ENSKMAP00000016535	LRRNT domain-containing protein. (74 aa)
	LOC108244167	Sema domain-containing protein. (1098 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1019 aa)
	fam53b	Family with sequence similarity 53 member B. (409 aa)
	ryk	Receptor like tyrosine kinase. (628 aa)
	LOC108248320	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2356 aa)
	cyfip1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
	vcl	Vinculin b. (1066 aa)
	LOC108243248	Si:ch211-113g11.6; Belongs to the semaphorin family. (643 aa)
	LOC108234096	Vinculin a. (1135 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (662 aa)
	ubap1	Ubiquitin associated protein 1. (462 aa)
	LOC108246708	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b. (1352 aa)
	LOC108247312	Unc-51 like autophagy activating kinase 1a. (919 aa)
	LOC108249015	Endothelin 2. (132 aa)
	LOC108244397	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (804 aa)
	FAM53B	Family with sequence similarity 53 member B. (451 aa)
	slit1	Slit homolog 1a (Drosophila). (1533 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108234096	LOC108238867	ENSKMAP00000025262	ENSKMAP00000003152	Vinculin a.	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a.	0.468
LOC108234096	LOC108246708	ENSKMAP00000025262	ENSKMAP00000026254	Vinculin a.	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b.	0.468
LOC108234096	vcl	ENSKMAP00000025262	ENSKMAP00000022443	Vinculin a.	Vinculin b.	0.900
LOC108235970	LOC108236984	ENSKMAP00000009699	ENSKMAP00000007141	Doublecortin-like kinase 1b.	Doublecortin-like kinase 1a.	0.507
LOC108235970	dcx	ENSKMAP00000009699	ENSKMAP00000013238	Doublecortin-like kinase 1b.	Uncharacterized protein.	0.650
LOC108236452	LOC108248320	ENSKMAP00000009654	ENSKMAP00000021265	Survival of motor neuron 1, telomeric.	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.407
LOC108236452	myo9a	ENSKMAP00000009654	ENSKMAP00000001935	Survival of motor neuron 1, telomeric.	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.407
LOC108236984	LOC108235970	ENSKMAP00000007141	ENSKMAP00000009699	Doublecortin-like kinase 1a.	Doublecortin-like kinase 1b.	0.507
LOC108236984	dcx	ENSKMAP00000007141	ENSKMAP00000013238	Doublecortin-like kinase 1a.	Uncharacterized protein.	0.650
LOC108238867	LOC108234096	ENSKMAP00000003152	ENSKMAP00000025262	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a.	Vinculin a.	0.468
LOC108238867	vcl	ENSKMAP00000003152	ENSKMAP00000022443	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a.	Vinculin b.	0.468
LOC108246708	LOC108234096	ENSKMAP00000026254	ENSKMAP00000025262	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b.	Vinculin a.	0.468
LOC108246708	vcl	ENSKMAP00000026254	ENSKMAP00000022443	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b.	Vinculin b.	0.468
LOC108247312	c9orf72	ENSKMAP00000026864	ENSKMAP00000008673	Unc-51 like autophagy activating kinase 1a.	Zgc:100846.	0.938
LOC108247312	ulk1	ENSKMAP00000026864	ENSKMAP00000017738	Unc-51 like autophagy activating kinase 1a.	Unc-51 like autophagy activating kinase 1.	0.903
LOC108247312	ulk2	ENSKMAP00000026864	ENSKMAP00000003244	Unc-51 like autophagy activating kinase 1a.	Unc-51 like autophagy activating kinase 2.	0.907
LOC108248320	LOC108236452	ENSKMAP00000021265	ENSKMAP00000009654	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Survival of motor neuron 1, telomeric.	0.407
LOC108249015	LOC108249163	ENSKMAP00000027542	ENSKMAP00000005893	Endothelin 2.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.958
LOC108249015	LOC108250397	ENSKMAP00000027542	ENSKMAP00000007254	Endothelin 2.	Endothelin 1.	0.608
LOC108249015	ednra	ENSKMAP00000027542	ENSKMAP00000005460	Endothelin 2.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.958