(38 nodes) Leukocyte proliferation network (Kryptolebias marmoratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cd79a	CD79a molecule, immunoglobulin-associated alpha. (221 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1122 aa)
	armc5	Armadillo repeat containing 5. (1186 aa)
	LOC108228916	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	LOC108233559	MALT paracaspase 1. (830 aa)
	il34	Uncharacterized protein. (201 aa)
	prkcd	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
	azi2	5-azacytidine induced 2. (397 aa)
	LOC108241222	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
	LOC108233117	E3 ubiquitin-protein ligase. (897 aa)
	Il20rb	Uncharacterized protein. (177 aa)
	ENSKMAP00000030182	MALT paracaspase 2. (570 aa)
	tnfsf13b	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (264 aa)
	LOC108236308	JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
	il7r	Fibronectin type-III domain-containing protein. (396 aa)
	LOC108245125	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (264 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1165 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (581 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (576 aa)
	LOC108237606	TNFR-Cys domain-containing protein. (301 aa)
	ENSKMAP00000003041	IGv domain-containing protein. (214 aa)
	lef1	Lymphoid enhancer-binding factor 1. (379 aa)
	LOC108231281	CD40 ligand; Belongs to the tumor necrosis factor family. (267 aa)
	sash3	SAM and SH3 domain containing 3. (395 aa)
	npr3	Natriuretic peptide receptor 3. (495 aa)
	NCSTN	Nicastrin. (701 aa)
	hells	Helicase, lymphoid specific. (851 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)
	LOC108231931	Uncharacterized protein. (272 aa)
	card11	Caspase recruitment domain family, member 11. (1044 aa)
	rassf5	Ras association domain family member 5. (476 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
	LOC108231686	E3 ubiquitin-protein ligase. (868 aa)
	nf1	Neurofibromin 1b. (2727 aa)
	ebi3	Epstein-Barr virus induced 3. (251 aa)
	txn	Thioredoxin; Belongs to the thioredoxin family. (106 aa)
	LOC108236077	JunB proto-oncogene, AP-1 transcription factor subunit b. (306 aa)
	rc3h2	Ring finger and CCCH-type domains 2. (1116 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000003041	LOC108231281	ENSKMAP00000003041	ENSKMAP00000002051	IGv domain-containing protein.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.690
ENSKMAP00000003041	LOC108237606	ENSKMAP00000003041	ENSKMAP00000003560	IGv domain-containing protein.	TNFR-Cys domain-containing protein.	0.662
ENSKMAP00000003041	ptprc	ENSKMAP00000003041	ENSKMAP00000005592	IGv domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.426
ENSKMAP00000030182	LOC108241222	ENSKMAP00000030182	ENSKMAP00000009376	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.457
ENSKMAP00000030182	card11	ENSKMAP00000030182	ENSKMAP00000021881	MALT paracaspase 2.	Caspase recruitment domain family, member 11.	0.904
ENSKMAP00000030182	prkcd	ENSKMAP00000030182	ENSKMAP00000026687	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.457
ENSKMAP00000030182	prkcq	ENSKMAP00000030182	ENSKMAP00000019454	MALT paracaspase 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.457
LOC108228916	LOC108231931	ENSKMAP00000011171	ENSKMAP00000022429	Transforming growth factor beta; Belongs to the TGF-beta family.	Uncharacterized protein.	0.450
LOC108228916	cd79a	ENSKMAP00000011171	ENSKMAP00000014543	Transforming growth factor beta; Belongs to the TGF-beta family.	CD79a molecule, immunoglobulin-associated alpha.	0.606
LOC108231281	ENSKMAP00000003041	ENSKMAP00000002051	ENSKMAP00000003041	CD40 ligand; Belongs to the tumor necrosis factor family.	IGv domain-containing protein.	0.690
LOC108231281	LOC108237606	ENSKMAP00000002051	ENSKMAP00000003560	CD40 ligand; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.976
LOC108231281	LOC108245125	ENSKMAP00000002051	ENSKMAP00000006492	CD40 ligand; Belongs to the tumor necrosis factor family.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.622
LOC108231281	ptprc	ENSKMAP00000002051	ENSKMAP00000005592	CD40 ligand; Belongs to the tumor necrosis factor family.	Protein tyrosine phosphatase receptor type C.	0.414
LOC108231281	tnfsf13b	ENSKMAP00000002051	ENSKMAP00000029645	CD40 ligand; Belongs to the tumor necrosis factor family.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.835
LOC108231686	LOC108233117	ENSKMAP00000019175	ENSKMAP00000009070	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
LOC108231686	ripk2	ENSKMAP00000019175	ENSKMAP00000005144	E3 ubiquitin-protein ligase.	Receptor-interacting serine-threonine kinase 2.	0.553
LOC108231931	LOC108228916	ENSKMAP00000022429	ENSKMAP00000011171	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.450
LOC108231931	LOC108245125	ENSKMAP00000022429	ENSKMAP00000006492	Uncharacterized protein.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.597
LOC108231931	il34	ENSKMAP00000022429	ENSKMAP00000009809	Uncharacterized protein.	Uncharacterized protein.	0.958
LOC108233117	LOC108231686	ENSKMAP00000009070	ENSKMAP00000019175	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901