(12 nodes) Proximal tubule development network (Kryptolebias marmoratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108233821	T-box transcription factor 2a. (643 aa)
	ENSKMAP00000002093	Polycystic kidney disease 1b. (2655 aa)
	LOC108245037	Odd-skipped related transcription factor 1. (268 aa)
	pkd2	Polycystic kidney disease 2. (911 aa)
	pkd1	Polycystic kidney disease 1a. (4448 aa)
	TBX2	T-box transcription factor 2. (682 aa)
	LOC108234774	Uncharacterized protein. (755 aa)
	LOC108241711	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
	LOC108241647	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	commd5	COMM domain containing 5. (211 aa)
	ENSKMAP00000011299	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (265 aa)
	LOC108233353	Uncharacterized protein. (761 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000002093	pkd2	ENSKMAP00000002093	ENSKMAP00000003620	Polycystic kidney disease 1b.	Polycystic kidney disease 2.	0.828
ENSKMAP00000011299	LOC108241647	ENSKMAP00000011299	ENSKMAP00000005282	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.552
ENSKMAP00000011299	LOC108241711	ENSKMAP00000011299	ENSKMAP00000005260	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.552
LOC108241647	ENSKMAP00000011299	ENSKMAP00000005282	ENSKMAP00000011299	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	0.552
LOC108241711	ENSKMAP00000011299	ENSKMAP00000005260	ENSKMAP00000011299	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	0.552
pkd1	pkd2	ENSKMAP00000024657	ENSKMAP00000003620	Polycystic kidney disease 1a.	Polycystic kidney disease 2.	0.828
pkd2	ENSKMAP00000002093	ENSKMAP00000003620	ENSKMAP00000002093	Polycystic kidney disease 2.	Polycystic kidney disease 1b.	0.828
pkd2	pkd1	ENSKMAP00000003620	ENSKMAP00000024657	Polycystic kidney disease 2.	Polycystic kidney disease 1a.	0.828