STRINGSTRING
hspa5 hspa5 faf1 faf1 map3k5 map3k5 piga piga emc9 emc9 get3 get3 derl1 derl1 LOC108242677 LOC108242677 LOC108242643 LOC108242643 LOC108251436 LOC108251436 LOC108241447 LOC108241447 srprb srprb dad1 dad1 emc7 emc7 tmem258 tmem258 sptssb sptssb emc3 emc3 LOC108235565 LOC108235565 camlg camlg ern1 ern1 pigh pigh sel1l sel1l LOC108240373 LOC108240373 LOC108241508 LOC108241508 pigu pigu pigk pigk amfr amfr zw10 zw10 LOC108247747 LOC108247747 hyou1 hyou1 ppib ppib pdia4 pdia4 gpaa1 gpaa1 LOC108245991 LOC108245991 mmgt1 mmgt1 pigt pigt derl2 derl2 aup1 aup1 LOC108241939 LOC108241939 vcp vcp LOC108250652 LOC108250652 fam167a fam167a emc1 emc1 STT3B STT3B insig1 insig1 emc6 emc6 sptlc1 sptlc1 sec63 sec63 ubxn7 ubxn7 nbas nbas ENSKMAP00000015212 ENSKMAP00000015212 rint1 rint1 stt3a stt3a LOC108250575 LOC108250575 abcb9 abcb9 emc8 emc8 faf2 faf2 Pigq Pigq ENSKMAP00000011158 ENSKMAP00000011158 emc10 emc10 rnf139 rnf139 sptssa sptssa spcs3 spcs3 LOC108230211 LOC108230211 fam8a1 fam8a1 rpn1 rpn1 pdia3 pdia3 sec61a1 sec61a1 syvn1 syvn1 LOC108237594 LOC108237594 spcs1 spcs1 rpn2 rpn2 LOC108249208 LOC108249208 sec61b sec61b ostc ostc dpm2 dpm2 ganab ganab emc4 emc4 ddost ddost pigm pigm ormdl1 ormdl1 ufd1 ufd1 derl3 derl3 ext2 ext2 selenos selenos emc2 emc2 pigc pigc insig2 insig2 krtcap2 krtcap2 srpra srpra ost4 ost4 spcs2 spcs2 hm13 hm13 pigs pigs alg14 alg14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (653 aa)
faf1Fas (TNFRSF6) associated factor 1. (671 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1369 aa)
pigaPhosphatidylinositol glycan anchor biosynthesis, class A. (489 aa)
emc9ER membrane protein complex subunit 9. (239 aa)
get3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (361 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (258 aa)
LOC108242677TAP binding protein (tapasin), tandem duplicate 2. (440 aa)
LOC108242643Transporter associated with antigen processing, subunit type a. (718 aa)
LOC108251436ER membrane protein complex subunit 3; Belongs to the EMC3 family. (257 aa)
LOC108241447Tumor suppressor candidate 3. (345 aa)
srprbSRP receptor subunit beta. (266 aa)
dad1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
emc7ER membrane protein complex subunit 7. (241 aa)
tmem258Transmembrane protein 258. (77 aa)
sptssbSerine palmitoyltransferase, small subunit B. (80 aa)
emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
LOC108235565Plug_translocon domain-containing protein. (476 aa)
camlgCalcium modulating ligand. (263 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1064 aa)
pighPhosphatidylinositol glycan anchor biosynthesis, class H. (181 aa)
sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (818 aa)
LOC108240373Si:ch211-1i11.3. (1328 aa)
LOC108241508Zgc:136908; Belongs to the AAA ATPase family. (808 aa)
piguPhosphatidylinositol glycan anchor biosynthesis, class U. (435 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (397 aa)
amfrAutocrine motility factor receptor b. (623 aa)
zw10Zw10 kinetochore protein. (766 aa)
LOC108247747STT3 oligosaccharyltransferase complex catalytic subunit B. (812 aa)
hyou1Hypoxia up-regulated 1. (939 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
pdia4Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (641 aa)
gpaa1Glycosylphosphatidylinositol anchor attachment 1. (615 aa)
LOC108245991Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (732 aa)
mmgt1Membrane magnesium transporter 1. (130 aa)
pigtPhosphatidylinositol glycan anchor biosynthesis, class T. (642 aa)
derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (220 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (402 aa)
LOC108241939Family with sequence similarity 8 member A1b. (331 aa)
vcpValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
LOC108250652Transporter associated with antigen processing, subunit type t, teleost specific. (711 aa)
fam167aFamily with sequence similarity 167 member Ab. (207 aa)
emc1ER membrane protein complex subunit 1. (962 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (804 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (252 aa)
emc6ER membrane protein complex subunit 6. (110 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (473 aa)
sec63SEC63 homolog, protein translocation regulator. (757 aa)
ubxn7UBX domain protein 7. (526 aa)
nbasNeuroblastoma amplified sequence. (2364 aa)
ENSKMAP00000015212Uncharacterized protein. (217 aa)
rint1RAD50 interactor 1. (786 aa)
stt3aSTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
LOC108250575Magnesium transporter 1. (328 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (797 aa)
emc8ER membrane protein complex subunit 8. (204 aa)
faf2Fas associated factor family member 2. (445 aa)
PigqUncharacterized protein. (166 aa)
ENSKMAP00000011158Uncharacterized protein. (81 aa)
emc10ER membrane protein complex subunit 10. (256 aa)
rnf139Ring finger protein 139. (715 aa)
sptssaSerine palmitoyltransferase, small subunit A. (68 aa)
spcs3Signal peptidase complex subunit 3. (180 aa)
LOC108230211Endoplasmic reticulum to nucleus signaling 2. (971 aa)
fam8a1Family with sequence similarity 8 member A1a. (282 aa)
rpn1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (600 aa)
pdia3Protein disulfide-isomerase. (490 aa)
sec61a1Plug_translocon domain-containing protein. (476 aa)
syvn1Synovial apoptosis inhibitor 1, synoviolin. (633 aa)
LOC108237594ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
spcs1Signal peptidase complex subunit 1. (110 aa)
rpn2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (647 aa)
LOC108249208ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
sec61bProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
ostcOligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa)
dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa)
ganabGlucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (951 aa)
emc4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (189 aa)
ddostDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (466 aa)
pigmGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (323 aa)
ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ufd1Ubiquitin recognition factor in ER associated degradation 1. (311 aa)
derl3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
selenosSelenoprotein S. (191 aa)
emc2ER membrane protein complex subunit 2. (297 aa)
pigcPhosphatidylinositol glycan anchor biosynthesis, class C. (294 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (242 aa)
krtcap2Keratinocyte associated protein 2. (136 aa)
srpraSRP receptor subunit alpha. (650 aa)
ost4Oligosaccharyltransferase complex subunit 4 (non-catalytic). (37 aa)
spcs2Signal peptidase complex subunit 2. (200 aa)
hm13Histocompatibility (minor) 13. (371 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (562 aa)
alg14ALG14 UDP-N-acetylglucosaminyltransferase subunit. (216 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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