STRINGSTRING
rptor rptor Cdkn2c Cdkn2c chek1 chek1 ENSKMAP00000029997 ENSKMAP00000029997 LOC108229807 LOC108229807 psme2 psme2 taok2 taok2 ccnd2 ccnd2 LOC112450491 LOC112450491 ercc2 ercc2 atad5 atad5 nsmce2 nsmce2 bub1 bub1 LOC108229869 LOC108229869 LOC108244970 LOC108244970 ENSKMAP00000028001 ENSKMAP00000028001 nop53 nop53 ENSKMAP00000027882 ENSKMAP00000027882 CUL3 CUL3 ndc80 ndc80 ENSKMAP00000027458 ENSKMAP00000027458 cunh10orf90 cunh10orf90 prmt2 prmt2 cenpf cenpf cenpe cenpe LOC108238656 LOC108238656 gpnmb gpnmb tm4sf5 tm4sf5 zwilch zwilch TFAP4 TFAP4 cdkn2d cdkn2d ino80 ino80 LOC108243680 LOC108243680 kntc1 kntc1 LOC108231213 LOC108231213 psme1 psme1 rbl1 rbl1 Cdca5 Cdca5 CLSPN CLSPN DONSON DONSON ENSKMAP00000024676 ENSKMAP00000024676 pkd1 pkd1 zw10 zw10 LOC108244280 LOC108244280 appl1 appl1 brca1 brca1 nabp1 nabp1 dtl dtl cdc27 cdc27 kank2 kank2 cdc23 cdc23 ENSKMAP00000023736 ENSKMAP00000023736 ambra1 ambra1 rad17 rad17 topbp1 topbp1 LOC108246606 LOC108246606 AIF1 AIF1 blm blm LOC108246065 LOC108246065 vps4a vps4a abraxas1 abraxas1 mad2l1 mad2l1 ENSKMAP00000021569 ENSKMAP00000021569 ENSKMAP00000021513 ENSKMAP00000021513 ENSKMAP00000021337 ENSKMAP00000021337 zfyve19 zfyve19 bub1b bub1b ENSKMAP00000020407 ENSKMAP00000020407 wac wac cdk1 cdk1 mecp2 mecp2 plk2 plk2 ENSKMAP00000020023 ENSKMAP00000020023 LOC108242536 LOC108242536 anapc15 anapc15 rad51c rad51c mad2l1bp mad2l1bp ENSKMAP00000019606 ENSKMAP00000019606 ube2c ube2c ENSKMAP00000019521 ENSKMAP00000019521 cdt1 cdt1 babam1 babam1 LOC108247652 LOC108247652 bub3 bub3 uimc1 uimc1 tpr tpr znf207 znf207 riok2 riok2 cdc26 cdc26 LOC108247629 LOC108247629 rb1 rb1 VPS4B-2 VPS4B-2 anapc4 anapc4 bcl2 bcl2 ENSKMAP00000017454 ENSKMAP00000017454 pla2g4a pla2g4a pinx1 pinx1 ccnd1 ccnd1 klhl22 klhl22 ccnb3 ccnb3 LSM10 LSM10 anapc5 anapc5 LOC108248224 LOC108248224 LOC108248232 LOC108248232 rint1 rint1 Kmt2e Kmt2e plk3 plk3 LOC108233174 LOC108233174 ENSKMAP00000014373 ENSKMAP00000014373 ENSKMAP00000014209 ENSKMAP00000014209 dcun1d3 dcun1d3 LOC108247550 LOC108247550 ctdspl ctdspl Brcc3 Brcc3 hus1 hus1 LOC108246975 LOC108246975 ENSKMAP00000013203 ENSKMAP00000013203 appl2 appl2 LOC108239511 LOC108239511 chfr chfr mad1l1 mad1l1 miip miip LOC108239009 LOC108239009 sass6 sass6 PLK1 PLK1 lsm11 lsm11 mre11 mre11 LOC108229746 LOC108229746 gen1 gen1 ENSKMAP00000011592 ENSKMAP00000011592 ENSKMAP00000011321 ENSKMAP00000011321 LOC108245220 LOC108245220 ENSKMAP00000010748 ENSKMAP00000010748 fbxo7 fbxo7 kif14 kif14 spdl1 spdl1 id2 id2 Crlf3 Crlf3 mblac1 mblac1 LOC108242249 LOC108242249 bcl7a bcl7a rfwd3 rfwd3 anapc7 anapc7 CPSF3 CPSF3 LOC108232730 LOC108232730 lcmt1 lcmt1 ENSKMAP00000009514 ENSKMAP00000009514 ENSKMAP00000009317 ENSKMAP00000009317 ENSKMAP00000009231 ENSKMAP00000009231 casp2 casp2 LOC108236986 LOC108236986 cdc14a cdc14a e2f1 e2f1 orc1 orc1 ENSKMAP00000008781 ENSKMAP00000008781 ticrr ticrr plrg1 plrg1 ENSKMAP00000008309 ENSKMAP00000008309 FZR1 FZR1 usp47 usp47 ENSKMAP00000008060 ENSKMAP00000008060 LOC108238293 LOC108238293 ZNF830 ZNF830 mnat1 mnat1 gnl3 gnl3 LOC108246328 LOC108246328 rgcc rgcc ccnh ccnh cdc73 cdc73 cdk5rap3 cdk5rap3 VPS4B VPS4B stox1 stox1 cdc16 cdc16 fbxo31 fbxo31 babam2 babam2 foxn3 foxn3 cdc6 cdc6 prkdc prkdc nbn nbn ttk ttk ENSKMAP00000004056 ENSKMAP00000004056 LOC108249691 LOC108249691 LOC108249674 LOC108249674 CTDSP1 CTDSP1 xpc xpc ENSKMAP00000003442 ENSKMAP00000003442 ddb1 ddb1 cdc7 cdc7 mfsd11 mfsd11 LOC108247965 LOC108247965 LOC108240497 LOC108240497 taok3 taok3 xrcc3 xrcc3 ENSKMAP00000002093 ENSKMAP00000002093 ecd ecd fhl1 fhl1 ints3 ints3 LOC108229311 LOC108229311 CDKN2A CDKN2A brd7 brd7 ENSKMAP00000001130 ENSKMAP00000001130 ENSKMAP00000000943 ENSKMAP00000000943 Atm Atm cul4b cul4b ENSKMAP00000000467 ENSKMAP00000000467 LOC108240964 LOC108240964 LOC108248489 LOC108248489 ENSKMAP00000000423 ENSKMAP00000000423 LOC108241005 LOC108241005 ENSKMAP00000000178 ENSKMAP00000000178 LOC108233748 LOC108233748 haspin haspin
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rptorRegulatory associated protein of MTOR, complex 1. (1332 aa)
Cdkn2cCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (159 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa)
ENSKMAP00000029997Reverse transcriptase domain-containing protein. (1252 aa)
LOC108229807Cullin 4A; Belongs to the cullin family. (746 aa)
psme2Proteasome activator subunit 2. (245 aa)
taok2TAO kinase 2b. (1155 aa)
ccnd2Cyclin D2, a; Belongs to the cyclin family. (340 aa)
LOC112450491Cyclin-dependent kinase inhibitor 1A. (159 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
atad5ATPase family AAA domain containing 5a. (1804 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (228 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1154 aa)
LOC108229869P53-induced death domain protein 1. (1005 aa)
LOC108244970E2F transcription factor 7. (615 aa)
ENSKMAP00000028001Reverse transcriptase domain-containing protein. (874 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (443 aa)
ENSKMAP00000027882Uncharacterized protein. (155 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
ndc80NDC80 kinetochore complex component. (640 aa)
ENSKMAP00000027458Reverse transcriptase domain-containing protein. (1256 aa)
cunh10orf90ALMS_motif domain-containing protein. (193 aa)
prmt2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (387 aa)
cenpfCentromere protein F. (2751 aa)
cenpeKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1672 aa)
LOC108238656CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b. (263 aa)
gpnmbGlycoprotein (transmembrane) nmb. (624 aa)
tm4sf5Transmembrane 4 L six family member 5. (201 aa)
zwilchZwilch kinetochore protein. (586 aa)
TFAP4Transcription factor AP-4. (349 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
ino80INO80 complex ATPase subunit. (1474 aa)
LOC108243680Uncharacterized protein. (420 aa)
kntc1Kinetochore associated 1. (2124 aa)
LOC108231213Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
psme1Proteasome activator subunit 1. (250 aa)
rbl1Retinoblastoma-like 1 (p107). (1034 aa)
Cdca5Cell division cycle associated 5. (265 aa)
CLSPNClaspin. (1213 aa)
DONSONDownstream neighbor of SON. (485 aa)
ENSKMAP00000024676Reverse transcriptase domain-containing protein. (1254 aa)
pkd1Polycystic kidney disease 1a. (4448 aa)
zw10Zw10 kinetochore protein. (766 aa)
LOC108244280CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1. (262 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (711 aa)
brca1Uncharacterized protein. (1354 aa)
nabp1Nucleic acid binding protein 1a. (219 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (621 aa)
cdc27Cell division cycle 27. (803 aa)
kank2KN motif and ankyrin repeat domains 2. (1027 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
ENSKMAP00000023736Reverse transcriptase domain-containing protein. (885 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1225 aa)
rad17RAD17 checkpoint clamp loader component. (528 aa)
topbp1DNA topoisomerase II binding protein 1. (1510 aa)
LOC108246606Cyclin-dependent kinase inhibitor 1Bb. (204 aa)
AIF1Allograft inflammatory factor 1. (152 aa)
blmBLM RecQ like helicase. (1384 aa)
LOC108246065Cell division cycle 25B. (528 aa)
vps4aVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (440 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (349 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
ENSKMAP00000021569Reverse transcriptase domain-containing protein. (1121 aa)
ENSKMAP00000021513Reverse transcriptase domain-containing protein. (1156 aa)
ENSKMAP00000021337Reverse transcriptase domain-containing protein. (876 aa)
zfyve19Zinc finger, FYVE domain containing 19. (426 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (428 aa)
ENSKMAP00000020407Reverse transcriptase domain-containing protein. (1258 aa)
wacWW domain containing adaptor with coiled-coil a. (593 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
mecp2Methyl CpG binding protein 2. (1055 aa)
plk2Serine/threonine-protein kinase PLK. (657 aa)
ENSKMAP00000020023annotation not available (828 aa)
LOC108242536G protein-coupled receptor 132a; Belongs to the G-protein coupled receptor 1 family. (298 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
rad51cRAD51 paralog C. (342 aa)
mad2l1bpMAD2L1 binding protein. (386 aa)
ENSKMAP00000019606Reverse transcriptase domain-containing protein. (1217 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (177 aa)
ENSKMAP00000019521Reverse transcriptase domain-containing protein. (1258 aa)
cdt1Chromatin licensing and DNA replication factor 1. (642 aa)
babam1BRISC and BRCA1 A complex member 1. (381 aa)
LOC108247652Transcription factor AP-4 (activating enhancer binding protein 4). (331 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
uimc1Uncharacterized protein. (976 aa)
tprTranslocated promoter region b, nuclear basket protein. (2200 aa)
znf207Zinc finger protein 207, b. (473 aa)
riok2RIO kinase 2 (yeast). (511 aa)
cdc26Cell division cycle 26 homolog. (97 aa)
LOC108247629CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2. (261 aa)
rb1Retinoblastoma 1. (915 aa)
VPS4B-2Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (508 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (799 aa)
bcl2BCL2 apoptosis regulator b. (297 aa)
ENSKMAP00000017454Reverse transcriptase domain-containing protein. (1273 aa)
pla2g4aPhospholipase A2. (747 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (364 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
klhl22Kelch-like family member 22. (630 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (401 aa)
LSM10LSM10, U7 small nuclear RNA associated. (121 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
LOC108248224Anaphase-promoting complex subunit 11. (84 aa)
LOC108248232APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
rint1RAD50 interactor 1. (786 aa)
Kmt2eLysine (K)-specific methyltransferase 2E. (430 aa)
plk3Serine/threonine-protein kinase PLK. (678 aa)
LOC108233174Cyclin D2, b; Belongs to the cyclin family. (294 aa)
ENSKMAP00000014373CDK5 regulatory subunit associated protein 2. (1099 aa)
ENSKMAP00000014209Uncharacterized protein. (182 aa)
dcun1d3DCN1-like protein. (326 aa)
LOC108247550Si:ch211-242b18.1. (1719 aa)
ctdsplCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (268 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (263 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
LOC108246975Cyclin-dependent kinase inhibitor 1Cb. (202 aa)
ENSKMAP00000013203Reverse transcriptase domain-containing protein. (1258 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
LOC108239511Translocated promoter region a, nuclear basket protein. (2040 aa)
chfrCheckpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (691 aa)
mad1l1Mitotic arrest deficient 1 like 1. (722 aa)
miipMigration and invasion inhibitory protein. (369 aa)
LOC108239009Four and a half LIM domains 1b. (280 aa)
sass6SAS-6 centriolar assembly protein. (587 aa)
PLK1Serine/threonine-protein kinase PLK. (582 aa)
lsm11LSM11, U7 small nuclear RNA associated. (322 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa)
LOC108229746Retinoblastoma-like 2 (p130). (645 aa)
gen1Chromo_2 domain-containing protein. (574 aa)
ENSKMAP00000011592Uncharacterized protein. (216 aa)
ENSKMAP00000011321annotation not available (1265 aa)
LOC108245220Si:ch211-137i24.10. (191 aa)
ENSKMAP00000010748Si:ch211-137i24.10. (190 aa)
fbxo7F-box protein 7. (466 aa)
kif14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1037 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
id2Inhibitor of DNA binding 2a. (139 aa)
Crlf3Uncharacterized protein. (85 aa)
mblac1Metallo-beta-lactamase domain containing 1. (257 aa)
LOC108242249Zgc:172079. (200 aa)
bcl7aBAF chromatin remodeling complex subunit BCL7A. (199 aa)
rfwd3Ring finger and WD repeat domain 3. (712 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (690 aa)
LOC108232730TAO kinase 3b. (496 aa)
lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
ENSKMAP00000009514Reverse transcriptase domain-containing protein. (489 aa)
ENSKMAP00000009317STIL centriolar assembly protein. (855 aa)
ENSKMAP00000009231Reverse transcriptase domain-containing protein. (987 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (439 aa)
LOC108236986ADAM metallopeptidase domain 17a. (847 aa)
cdc14aCell division cycle 14Ab. (595 aa)
e2f1E2F transcription factor 1. (452 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (695 aa)
ENSKMAP00000008781Reverse transcriptase domain-containing protein. (1162 aa)
ticrrUncharacterized protein. (1675 aa)
plrg1Pleiotropic regulator 1. (510 aa)
ENSKMAP00000008309Reverse transcriptase domain-containing protein. (1265 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (496 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
ENSKMAP00000008060Reverse transcriptase domain-containing protein. (975 aa)
LOC108238293Fizzy/cell division cycle 20 related 1b. (487 aa)
ZNF830Zinc finger protein 830. (339 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (547 aa)
LOC108246328TAO kinase 1a. (1024 aa)
rgccRegulator of cell cycle. (175 aa)
ccnhCyclin H; Belongs to the cyclin family. (333 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (505 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (412 aa)
stox1Storkhead box 1. (1099 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
fbxo31F-box protein 31. (575 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
foxn3Checkpoint suppressor 1. (483 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (575 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4049 aa)
nbnNibrin. (832 aa)
ttkTtk protein kinase. (994 aa)
ENSKMAP00000004056Uncharacterized protein. (156 aa)
LOC108249691ADAM metallopeptidase domain 17b. (835 aa)
LOC108249674Cleavage and polyadenylation specific factor 3. (686 aa)
CTDSP1CTD small phosphatase 1. (305 aa)
xpcXeroderma pigmentosum, complementation group C. (935 aa)
ENSKMAP00000003442Reverse transcriptase domain-containing protein. (1237 aa)
ddb1Damage-specific DNA binding protein 1. (1075 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (547 aa)
mfsd11Major facilitator superfamily domain containing 11. (454 aa)
LOC108247965WW domain-containing protein. (525 aa)
LOC108240497CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
taok3TAO kinase 3a. (903 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa)
ENSKMAP00000002093Polycystic kidney disease 1b. (2655 aa)
ecdEcdysoneless homolog (Drosophila). (706 aa)
fhl1Four and a half LIM domains 1a. (339 aa)
ints3Integrator complex subunit 3. (1019 aa)
LOC108229311Uncharacterized protein. (209 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (124 aa)
brd7Bromodomain containing 7. (620 aa)
ENSKMAP00000001130Reverse transcriptase domain-containing protein. (1110 aa)
ENSKMAP00000000943Uncharacterized protein. (144 aa)
AtmUncharacterized protein. (130 aa)
cul4bCullin 4B; Belongs to the cullin family. (869 aa)
ENSKMAP00000000467TAN domain-containing protein. (123 aa)
LOC108240964Uncharacterized protein. (240 aa)
LOC108248489TAO kinase 1b. (1016 aa)
ENSKMAP00000000423Reverse transcriptase domain-containing protein. (1066 aa)
LOC108241005Cyclin-dependent kinase inhibitor 1D. (175 aa)
ENSKMAP00000000178Reverse transcriptase domain-containing protein. (1096 aa)
LOC108233748Cell division cycle 14B. (525 aa)
haspinSi:dkeyp-26a9.2. (1228 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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