39 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pms2	PMS1 homolog 2, mismatch repair system component. (857 aa)
	fanci	FA complementation group I. (1317 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	phf21a	PHD finger protein 21Ab. (554 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	fancd2	FA complementation group D2. (1361 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (629 aa)
	brca1	Uncharacterized protein. (1354 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa)
	nhej1	Nonhomologous end-joining factor 1. (308 aa)
	ascc1	Activating signal cointegrator 1 complex subunit 1. (354 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	zswim7	Zinc finger, SWIM-type containing 7. (138 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
	LOC108234481	Uncharacterized protein. (270 aa)
	pold1	DNA polymerase. (1105 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (837 aa)
	dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (411 aa)
	palb2	PALB2_WD40 domain-containing protein. (1335 aa)
	xrcc4	X-ray repair complementing defective repair in Chinese hamster cells 4. (343 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa)
	LOC108229664	PMS1 homolog 1, mismatch repair system component. (568 aa)
	brca2	BRCA2 DNA repair associated. (2641 aa)
	swsap1	SWIM-type zinc finger 7 associated protein 1. (278 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1702 aa)
	ascc2	Activating signal cointegrator 1 complex subunit 2. (761 aa)
	ENSKMAP00000005281	Uncharacterized protein. (165 aa)
	ENSKMAP00000000467	TAN domain-containing protein. (123 aa)
	Atm	Uncharacterized protein. (130 aa)
	lig4	DNA ligase. (922 aa)
	xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa)
	paxx	PAXX non-homologous end joining factor. (191 aa)
	msh3	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (972 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (935 aa)
	mlh3	MutL homolog 3 (E. coli). (1121 aa)
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4049 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSKMAP00000000467	ENSKMAP00000000507	ENSKMAP00000000467	Uncharacterized protein.	TAN domain-containing protein.	0.926
Atm	brca1	ENSKMAP00000000507	ENSKMAP00000024393	Uncharacterized protein.	Uncharacterized protein.	0.991
Atm	brca2	ENSKMAP00000000507	ENSKMAP00000010397	Uncharacterized protein.	BRCA2 DNA repair associated.	0.831
Atm	dclre1c	ENSKMAP00000000507	ENSKMAP00000012753	Uncharacterized protein.	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae).	0.620
Atm	ercc1	ENSKMAP00000000507	ENSKMAP00000027419	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.594
Atm	ercc4	ENSKMAP00000000507	ENSKMAP00000029520	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.595
Atm	fancd2	ENSKMAP00000000507	ENSKMAP00000027787	Uncharacterized protein.	FA complementation group D2.	0.624
Atm	fanci	ENSKMAP00000000507	ENSKMAP00000004789	Uncharacterized protein.	FA complementation group I.	0.528
Atm	lig4	ENSKMAP00000000507	ENSKMAP00000001469	Uncharacterized protein.	DNA ligase.	0.623
Atm	mlh1	ENSKMAP00000000507	ENSKMAP00000011476	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.763
Atm	mlh3	ENSKMAP00000000507	ENSKMAP00000003677	Uncharacterized protein.	MutL homolog 3 (E. coli).	0.579
Atm	msh2	ENSKMAP00000000507	ENSKMAP00000015699	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.680
Atm	msh3	ENSKMAP00000000507	ENSKMAP00000003197	Uncharacterized protein.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.484
Atm	msh6	ENSKMAP00000000507	ENSKMAP00000022133	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.671
Atm	palb2	ENSKMAP00000000507	ENSKMAP00000012218	Uncharacterized protein.	PALB2_WD40 domain-containing protein.	0.683
Atm	pms2	ENSKMAP00000000507	ENSKMAP00000011431	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.531
Atm	pold1	ENSKMAP00000000507	ENSKMAP00000013397	Uncharacterized protein.	DNA polymerase.	0.543
Atm	prkdc	ENSKMAP00000000507	ENSKMAP00000004514	Uncharacterized protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.696
Atm	tp53bp1	ENSKMAP00000000507	ENSKMAP00000009403	Uncharacterized protein.	Tumor protein p53 binding protein, 1.	0.942
Atm	xpa	ENSKMAP00000000507	ENSKMAP00000028000	Uncharacterized protein.	Xeroderma pigmentosum, complementation group A.	0.489