46 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	klhl20	Kelch-like family member 20. (604 aa)
	daxx	Death-domain associated protein. (756 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	LOC108233935	RING-type domain-containing protein. (565 aa)
	nagpa	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (598 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (284 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (425 aa)
	n4bp1	Nedd4 binding protein 1. (734 aa)
	mlip	Uncharacterized protein. (827 aa)
	LOC108229273	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (378 aa)
	tp53inp2	Uncharacterized protein. (302 aa)
	ENSKMAP00000024942	Uncharacterized protein. (191 aa)
	ENSKMAP00000024917	Uncharacterized protein. (183 aa)
	ENSKMAP00000024903	Uncharacterized protein. (286 aa)
	ENSKMAP00000024756	Uncharacterized protein. (257 aa)
	LOC108246670	CW-type domain-containing protein. (631 aa)
	rnf4	RING-type domain-containing protein. (198 aa)
	Ciita	NACHT domain-containing protein. (925 aa)
	zbtb16	Zinc finger and BTB domain containing 16a. (699 aa)
	LOC108249533	Heat shock transcription factor 4. (431 aa)
	blm	BLM RecQ like helicase. (1384 aa)
	LOC108251266	Endo/exonuclease/phosphatase domain-containing protein. (311 aa)
	rpain	RPA interacting protein. (227 aa)
	LOC108237887	Zgc:162297. (269 aa)
	LOC108237885	Si:ch211-260e23.9. (170 aa)
	LOC108240719	Small ubiquitin-related modifier. (94 aa)
	LOC108232577	Small ubiquitin-related modifier. (94 aa)
	casp8ap2	Uncharacterized protein. (1806 aa)
	trim8	Tripartite motif containing 8b. (566 aa)
	chfr	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (691 aa)
	rnf6	Ring finger protein (C3H2C3 type) 6. (719 aa)
	ankrd1	Ankyrin repeat domain 1a (cardiac muscle). (314 aa)
	rnf111	Ring finger protein 111. (1023 aa)
	LOC108240530	Germ cell nuclear acidic peptidase. (579 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (360 aa)
	LOC108248076	Checkpoint kinase 2. (534 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (940 aa)
	calcoco2	SKICH domain-containing protein. (593 aa)
	hsf2	Heat shock transcription factor 2. (556 aa)
	LOC108248615	KH and NYN domain containing. (1004 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	LOC108242722	Small ubiquitin-related modifier. (96 aa)
	LOC108236913	Transmembrane phosphatase with tensin homology. (511 aa)
	HSF1	Heat shock transcription factor 1. (551 aa)
	rdm1	RRM domain-containing protein. (276 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000024756	ENSKMAP00000024917	ENSKMAP00000024756	ENSKMAP00000024917	Uncharacterized protein.	Uncharacterized protein.	0.411
ENSKMAP00000024756	LOC108246670	ENSKMAP00000024756	ENSKMAP00000024715	Uncharacterized protein.	CW-type domain-containing protein.	0.899
ENSKMAP00000024903	ENSKMAP00000024917	ENSKMAP00000024903	ENSKMAP00000024917	Uncharacterized protein.	Uncharacterized protein.	0.699
ENSKMAP00000024903	LOC108246670	ENSKMAP00000024903	ENSKMAP00000024715	Uncharacterized protein.	CW-type domain-containing protein.	0.919
ENSKMAP00000024917	ENSKMAP00000024756	ENSKMAP00000024917	ENSKMAP00000024756	Uncharacterized protein.	Uncharacterized protein.	0.411
ENSKMAP00000024917	ENSKMAP00000024903	ENSKMAP00000024917	ENSKMAP00000024903	Uncharacterized protein.	Uncharacterized protein.	0.699
ENSKMAP00000024917	ENSKMAP00000024942	ENSKMAP00000024917	ENSKMAP00000024942	Uncharacterized protein.	Uncharacterized protein.	0.531
ENSKMAP00000024917	LOC108246670	ENSKMAP00000024917	ENSKMAP00000024715	Uncharacterized protein.	CW-type domain-containing protein.	0.453
ENSKMAP00000024942	ENSKMAP00000024917	ENSKMAP00000024942	ENSKMAP00000024917	Uncharacterized protein.	Uncharacterized protein.	0.531
ENSKMAP00000024942	LOC108246670	ENSKMAP00000024942	ENSKMAP00000024715	Uncharacterized protein.	CW-type domain-containing protein.	0.899
HSF1	RPA1	ENSKMAP00000002441	ENSKMAP00000000242	Heat shock transcription factor 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.461
HSF1	rpa1	ENSKMAP00000002441	ENSKMAP00000007505	Heat shock transcription factor 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.461
LOC108229273	pten	ENSKMAP00000025004	ENSKMAP00000026430	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.901
LOC108232577	LOC108251266	ENSKMAP00000016078	ENSKMAP00000020842	Small ubiquitin-related modifier.	Endo/exonuclease/phosphatase domain-containing protein.	0.505
LOC108232577	RPA1	ENSKMAP00000016078	ENSKMAP00000000242	Small ubiquitin-related modifier.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.473
LOC108232577	blm	ENSKMAP00000016078	ENSKMAP00000022385	Small ubiquitin-related modifier.	BLM RecQ like helicase.	0.709
LOC108232577	daxx	ENSKMAP00000016078	ENSKMAP00000029065	Small ubiquitin-related modifier.	Death-domain associated protein.	0.644
LOC108232577	rnf111	ENSKMAP00000016078	ENSKMAP00000009954	Small ubiquitin-related modifier.	Ring finger protein 111.	0.447
LOC108232577	rnf4	ENSKMAP00000016078	ENSKMAP00000024382	Small ubiquitin-related modifier.	RING-type domain-containing protein.	0.716
LOC108232577	rnf6	ENSKMAP00000016078	ENSKMAP00000012252	Small ubiquitin-related modifier.	Ring finger protein (C3H2C3 type) 6.	0.442