STRINGSTRING
pot1 pot1 pold3 pold3 lig1 lig1 dscc1 dscc1 pola2 pola2 prim2 prim2 terf2 terf2 rfc3 rfc3 rpa1 rpa1 ctc1 ctc1 fen1 fen1 rcbtb2 rcbtb2 chtf8 chtf8 LOC108244487 LOC108244487 pcna pcna RCBTB1 RCBTB1 DNA2 DNA2 stn1 stn1 pola1 pola1 prim1 prim1 LOC108245905 LOC108245905 rfc4 rfc4 ten1 ten1 pold2 pold2 rfc1 rfc1 RPA1 RPA1 rfc5 rfc5 blm blm LOC108244139 LOC108244139 rpa2 rpa2 ENSKMAP00000013709 ENSKMAP00000013709 terf2ip terf2ip pold1 pold1 rfc2 rfc2 pold4 pold4 LOC108248126 LOC108248126 chtf18 chtf18 terf1 terf1 rpa3 rpa3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pot1Protection of telomeres 1 homolog. (770 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
lig1DNA ligase. (1010 aa)
dscc1DNA replication and sister chromatid cohesion 1. (390 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (516 aa)
terf2HTH myb-type domain-containing protein. (603 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
ctc1Uncharacterized protein. (993 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (136 aa)
LOC108244487Zgc:110269. (346 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
DNA2DNA replication helicase/nuclease 2. (1388 aa)
stn1STN1 subunit of CST complex. (315 aa)
pola1DNA polymerase. (1476 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (427 aa)
LOC108245905TERF1 (TRF1)-interacting nuclear factor 2. (570 aa)
rfc4Replication factor C (activator 1) 4. (388 aa)
ten1TEN1 subunit of CST complex. (135 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
rfc1Replication factor C subunit 1. (1180 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rfc5Replication factor C (activator 1) 5. (339 aa)
blmBLM RecQ like helicase. (1384 aa)
LOC108244139Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
rpa2RPA_C domain-containing protein. (274 aa)
ENSKMAP00000013709Uncharacterized protein. (437 aa)
terf2ipUncharacterized protein. (682 aa)
pold1DNA polymerase. (1105 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
pold4Uncharacterized protein. (110 aa)
LOC108248126RPA_C domain-containing protein. (199 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (775 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (366 aa)
rpa3Replication protein A 14kDa subunit. (122 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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