68 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108236256	Growth factor receptor-bound protein 2b. (224 aa)
	ubb	Uncharacterized protein. (270 aa)
	LOC108235488	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (570 aa)
	RNF222	Ring finger protein 222. (269 aa)
	LOC108244166	Rho guanine nucleotide exchange factor (GEF) 7b. (800 aa)
	pxn	Uncharacterized protein. (894 aa)
	cd2ap	Uncharacterized protein. (556 aa)
	egf	Epidermal growth factor. (1111 aa)
	LOC108243005	Zgc:55558. (187 aa)
	lrig1	Leucine-rich repeats and immunoglobulin-like domains 1. (1038 aa)
	LOC108238424	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC108235454	Uncharacterized protein. (190 aa)
	LOC108235453	Uncharacterized protein. (197 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (351 aa)
	tgfa	Transforming growth factor, alpha. (242 aa)
	CDC42	Cell division cycle 42. (197 aa)
	LOC108239547	SH3-domain GRB2-like 1a. (362 aa)
	pag1	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (437 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (896 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (861 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (514 aa)
	LOC108233675	Uncharacterized protein. (161 aa)
	LOC108233673	EGF-like domain-containing protein. (168 aa)
	LOC108248645	Cell division cycle 42. (191 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC108249741	Uncharacterized protein. (351 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	ptpn3	Protein tyrosine phosphatase non-receptor type 3. (881 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	KRAS	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
	gab1	GRB2-associated binding protein 1. (786 aa)
	LOC108248584	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	aamp	Angio-associated, migratory cell protein. (419 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	lrig3	Leucine-rich repeats and immunoglobulin-like domains 3. (1026 aa)
	ENSKMAP00000003379	SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
	sh3gl1	SH3-domain GRB2-like 1b. (351 aa)
	ENSKMAP00000002967	Uncharacterized protein. (274 aa)
	LOC108237634	Tyrosine-protein kinase. (549 aa)
	LOC108239982	HRas proto-oncogene, GTPase a. (189 aa)
	CSK	Tyrosine-protein kinase. (453 aa)
	LOC108232479	Rho guanine nucleotide exchange factor (GEF) 7a. (800 aa)
	LOC108229870	Tyrosine-protein kinase. (447 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (521 aa)
	LOC108230693	Leupaxin. (399 aa)
	LOC108250222	PH domain-containing protein. (704 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)
	eps15	Epidermal growth factor receptor pathway substrate 15. (1102 aa)
	eps15l1	Uncharacterized protein. (1306 aa)
	sh3kbp1	SH3-domain kinase binding protein 1. (612 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (482 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1398 aa)
	LOC108239857	Uncharacterized protein. (836 aa)
	ptprk	Protein tyrosine phosphatase receptor type K. (1415 aa)
	LOC108242678	Uncharacterized protein. (204 aa)
	LOC108242040	Heparin-binding EGF-like growth factor a. (234 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
	LOC108238085	Uncharacterized protein. (881 aa)
	lrig2	Leucine-rich repeats and immunoglobulin-like domains 2. (1060 aa)
	LOC108246056	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	ENSKMAP00000020331	Sprouty RTK signaling antagonist 2. (329 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	ptprt	Protein tyrosine phosphatase receptor type T. (1519 aa)
	sh3d21	SH3 domain containing 21. (485 aa)
	ENSKMAP00000018464	Uncharacterized protein. (73 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (779 aa)
	LOC108231089	Betacellulin, epidermal growth factor family member. (184 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	LOC108230693	ENSKMAP00000010448	ENSKMAP00000001024	Cell division cycle 42.	Leupaxin.	0.459
CDC42	LOC108232479	ENSKMAP00000010448	ENSKMAP00000002038	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7a.	0.688
CDC42	LOC108233675	ENSKMAP00000010448	ENSKMAP00000007418	Cell division cycle 42.	Uncharacterized protein.	0.532
CDC42	LOC108235488	ENSKMAP00000010448	ENSKMAP00000016363	Cell division cycle 42.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.539
CDC42	LOC108236256	ENSKMAP00000010448	ENSKMAP00000017060	Cell division cycle 42.	Growth factor receptor-bound protein 2b.	0.686
CDC42	LOC108237634	ENSKMAP00000010448	ENSKMAP00000002899	Cell division cycle 42.	Tyrosine-protein kinase.	0.497
CDC42	LOC108238085	ENSKMAP00000010448	ENSKMAP00000023932	Cell division cycle 42.	Uncharacterized protein.	0.539
CDC42	LOC108238424	ENSKMAP00000010448	ENSKMAP00000011820	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.634
CDC42	LOC108239857	ENSKMAP00000010448	ENSKMAP00000027045	Cell division cycle 42.	Uncharacterized protein.	0.459
CDC42	LOC108242040	ENSKMAP00000010448	ENSKMAP00000025271	Cell division cycle 42.	Heparin-binding EGF-like growth factor a.	0.563
CDC42	LOC108244166	ENSKMAP00000010448	ENSKMAP00000014701	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.688
CDC42	LOC108248584	ENSKMAP00000010448	ENSKMAP00000004760	Cell division cycle 42.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.634
CDC42	PIK3CA	ENSKMAP00000010448	ENSKMAP00000005670	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.634
CDC42	SRC	ENSKMAP00000010448	ENSKMAP00000019871	Cell division cycle 42.	Tyrosine-protein kinase.	0.497
CDC42	TGFB1I1	ENSKMAP00000010448	ENSKMAP00000028673	Cell division cycle 42.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.459
CDC42	cbl	ENSKMAP00000010448	ENSKMAP00000020250	Cell division cycle 42.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.539
CDC42	cd2ap	ENSKMAP00000010448	ENSKMAP00000014489	Cell division cycle 42.	Uncharacterized protein.	0.461
CDC42	egf	ENSKMAP00000010448	ENSKMAP00000013694	Cell division cycle 42.	Epidermal growth factor.	0.627
CDC42	pxn	ENSKMAP00000010448	ENSKMAP00000014617	Cell division cycle 42.	Uncharacterized protein.	0.459
CDC42	rps27a	ENSKMAP00000010448	ENSKMAP00000004139	Cell division cycle 42.	Ribosomal protein S27a.	0.601