34 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
	LOC108239982	HRas proto-oncogene, GTPase a. (189 aa)
	ENSKMAP00000002577	SH2 domain-containing protein. (195 aa)
	nck2	Cytoplasmic protein. (396 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (316 aa)
	LOC108243804	Signal transducer and activator of transcription. (791 aa)
	LOC108248584	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	KRAS	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
	pdgfrb	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1107 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1067 aa)
	nedd9	Neural precursor cell expressed, developmentally down-regulated 9. (777 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (861 aa)
	LOC108245177	Signal transducer and activator of transcription. (788 aa)
	LOC108244589	Signal transducer and activator of transcription. (774 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (896 aa)
	LOC108238424	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC108248149	V-crk avian sarcoma virus CT10 oncogene homolog. (307 aa)
	bcar1	BCAR1 scaffold protein, Cas family member. (980 aa)
	LOC108243005	Zgc:55558. (187 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1115 aa)
	LOC108237947	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
	LOC108232032	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (569 aa)
	nck1	Cytoplasmic protein. (393 aa)
	LOC108236256	Growth factor receptor-bound protein 2b. (224 aa)
	LOC108237634	Tyrosine-protein kinase. (549 aa)
	LOC108248979	Growth factor receptor bound protein 7. (518 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
	cass4	Cas scaffold protein family member 4. (788 aa)
	LOC108236096	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (506 aa)
	LOC108246548	CRK proto-oncogene, adaptor protein. (310 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	pdgfa	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC108236256	ENSKMAP00000007641	ENSKMAP00000017060	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.678
CSDE1	LOC108237634	ENSKMAP00000007641	ENSKMAP00000002899	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.428
CSDE1	LOC108238424	ENSKMAP00000007641	ENSKMAP00000011820	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
CSDE1	LOC108248584	ENSKMAP00000007641	ENSKMAP00000004760	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.518
CSDE1	PIK3CA	ENSKMAP00000007641	ENSKMAP00000005670	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
CSDE1	SRC	ENSKMAP00000007641	ENSKMAP00000019871	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.428
CSDE1	pdgfrb	ENSKMAP00000007641	ENSKMAP00000005415	Cold shock domain containing E1, RNA-binding.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.500
CSDE1	pik3cb	ENSKMAP00000007641	ENSKMAP00000002735	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.518
CSDE1	rapgef1	ENSKMAP00000007641	ENSKMAP00000013920	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.471
CSDE1	rasa1	ENSKMAP00000007641	ENSKMAP00000006945	Cold shock domain containing E1, RNA-binding.	RAS p21 protein activator (GTPase activating protein) 1a.	0.799
ENSKMAP00000002577	LOC108237634	ENSKMAP00000002577	ENSKMAP00000002899	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.485
ENSKMAP00000002577	LOC108243804	ENSKMAP00000002577	ENSKMAP00000026896	SH2 domain-containing protein.	Signal transducer and activator of transcription.	0.523
ENSKMAP00000002577	LOC108244589	ENSKMAP00000002577	ENSKMAP00000008376	SH2 domain-containing protein.	Signal transducer and activator of transcription.	0.555
ENSKMAP00000002577	LOC108245177	ENSKMAP00000002577	ENSKMAP00000007917	SH2 domain-containing protein.	Signal transducer and activator of transcription.	0.526
ENSKMAP00000002577	SRC	ENSKMAP00000002577	ENSKMAP00000019871	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.485
ENSKMAP00000002577	pdgfrb	ENSKMAP00000002577	ENSKMAP00000005415	SH2 domain-containing protein.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.552
KRAS	LOC108236256	ENSKMAP00000005296	ENSKMAP00000017060	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Growth factor receptor-bound protein 2b.	0.678
KRAS	LOC108237634	ENSKMAP00000005296	ENSKMAP00000002899	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Tyrosine-protein kinase.	0.534
KRAS	LOC108238424	ENSKMAP00000005296	ENSKMAP00000011820	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.858
KRAS	LOC108239982	ENSKMAP00000005296	ENSKMAP00000002614	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	HRas proto-oncogene, GTPase a.	0.911