31 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108230757	SHC (Src homology 2 domain containing) transforming protein 2. (738 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (450 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (441 aa)
	ENSKMAP00000027218	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (208 aa)
	ralb	V-ral simian leukemia viral oncogene homolog Ba (ras related). (207 aa)
	LOC108231487	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (195 aa)
	nkpd1	NTPase, KAP family P-loop domain containing 1. (724 aa)
	LOC108249685	Kinase D-interacting substrate 220b. (1693 aa)
	LOC108246548	CRK proto-oncogene, adaptor protein. (310 aa)
	LOC108235782	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (393 aa)
	SHC3	SHC adaptor protein 3. (671 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (316 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1115 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (532 aa)
	LOC108243005	Zgc:55558. (187 aa)
	LOC108242980	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
	LOC108248149	V-crk avian sarcoma virus CT10 oncogene homolog. (307 aa)
	LOC108234850	ANK_REP_REGION domain-containing protein. (1716 aa)
	LOC108246862	Mitogen-activated protein kinase. (356 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	KRAS	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
	ralgds	Ral guanine nucleotide dissociation stimulator. (862 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	LOC108244594	Mitogen-activated protein kinase. (359 aa)
	LOC108233159	Mitogen-activated protein kinase. (364 aa)
	LOC108228880	Uncharacterized protein. (201 aa)
	LOC108241209	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (423 aa)
	LOC108251047	Mitogen-activated protein kinase. (361 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (861 aa)
	LOC108230441	V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
	LOC108239982	HRas proto-oncogene, GTPase a. (189 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC108242980	ENSKMAP00000007641	ENSKMAP00000012530	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
CSDE1	SHC3	ENSKMAP00000007641	ENSKMAP00000019878	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 3.	0.436
CSDE1	frs2	ENSKMAP00000007641	ENSKMAP00000013799	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 2b.	0.431
CSDE1	map2k1	ENSKMAP00000007641	ENSKMAP00000026267	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.572
CSDE1	map2k2	ENSKMAP00000007641	ENSKMAP00000004330	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.572
CSDE1	mapk1	ENSKMAP00000007641	ENSKMAP00000005892	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
CSDE1	ralgds	ENSKMAP00000007641	ENSKMAP00000004927	Cold shock domain containing E1, RNA-binding.	Ral guanine nucleotide dissociation stimulator.	0.724
CSDE1	rapgef1	ENSKMAP00000007641	ENSKMAP00000013920	Cold shock domain containing E1, RNA-binding.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.471
ENSKMAP00000027218	LOC108234850	ENSKMAP00000027218	ENSKMAP00000010068	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	ANK_REP_REGION domain-containing protein.	0.405
ENSKMAP00000027218	LOC108249685	ENSKMAP00000027218	ENSKMAP00000003337	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Kinase D-interacting substrate 220b.	0.405
ENSKMAP00000027218	frs2	ENSKMAP00000027218	ENSKMAP00000013799	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Fibroblast growth factor receptor substrate 2b.	0.427
ENSKMAP00000027218	nkpd1	ENSKMAP00000027218	ENSKMAP00000029549	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	NTPase, KAP family P-loop domain containing 1.	0.405
ENSKMAP00000027218	rapgef1	ENSKMAP00000027218	ENSKMAP00000013920	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.569
KRAS	LOC108239982	ENSKMAP00000005296	ENSKMAP00000002614	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	HRas proto-oncogene, GTPase a.	0.911
KRAS	LOC108242980	ENSKMAP00000005296	ENSKMAP00000012530	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
KRAS	LOC108243005	ENSKMAP00000005296	ENSKMAP00000013546	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Zgc:55558.	0.901
KRAS	SHC3	ENSKMAP00000005296	ENSKMAP00000019878	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	SHC adaptor protein 3.	0.436
KRAS	frs2	ENSKMAP00000005296	ENSKMAP00000013799	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Fibroblast growth factor receptor substrate 2b.	0.431
KRAS	map2k1	ENSKMAP00000005296	ENSKMAP00000026267	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.572
KRAS	map2k2	ENSKMAP00000005296	ENSKMAP00000004330	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.572