STRINGSTRING
mapk1 mapk1 LOC108230630 LOC108230630 gtf2f2 gtf2f2 FGF6 FGF6 hnrnpa1 hnrnpa1 LOC108241470 LOC108241470 ppp2ca ppp2ca fgfr1 fgfr1 LOC108230049 LOC108230049 ENSKMAP00000025685 ENSKMAP00000025685 LOC108238084 LOC108238084 LOC108237351 LOC108237351 plcg1 plcg1 ANOS1 ANOS1 polr2b polr2b LOC108238085 LOC108238085 LOC108246621 LOC108246621 LOC108239148 LOC108239148 ENSKMAP00000022213 ENSKMAP00000022213 polr2a polr2a LOC108248915 LOC108248915 polr2c polr2c SPRED2 SPRED2 ENSKMAP00000020331 ENSKMAP00000020331 cbl cbl LOC108237956 LOC108237956 SRC SRC GALNT3 GALNT3 flrt3 flrt3 polr2j polr2j polr2f polr2f mknk2 mknk2 LOC108250029 LOC108250029 LOC108228343 LOC108228343 fgf3 fgf3 fgf4 fgf4 LOC108250222 LOC108250222 gtf2f1 gtf2f1 LOC108240442 LOC108240442 polr2i polr2i mknk1 mknk1 flrt2 flrt2 LOC108239982 LOC108239982 LOC108237634 LOC108237634 ENSKMAP00000003379 ENSKMAP00000003379 LOC108238827 LOC108238827 rps27a rps27a polr2l polr2l fgf5 fgf5 NCBP1 NCBP1 LOC108248584 LOC108248584 gab1 gab1 fgf7 fgf7 LOC108231882 LOC108231882 KRAS KRAS PIK3CA PIK3CA LOC108231354 LOC108231354 fgf19 fgf19 LOC108236256 LOC108236256 LOC108239072 LOC108239072 LOC108238369 LOC108238369 ubb ubb LOC108235488 LOC108235488 LOC108231995 LOC108231995 LOC108233785 LOC108233785 LOC108251146 LOC108251146 PTBP2 PTBP2 LOC108249920 LOC108249920 fgf17 fgf17 ppp2cb ppp2cb polr2g polr2g spred1 spred1 fgfrl1 fgfrl1 fgf23 fgf23 LOC108233283 LOC108233283 Polr2d Polr2d frs2 frs2 LOC108232617 LOC108232617 LOC108243005 LOC108243005 fgf1 fgf1 klb klb ncbp2 ncbp2 LOC108239527 LOC108239527 LOC108243526 LOC108243526 LOC108242980 LOC108242980 fgfr2 fgfr2 LOC108242389 LOC108242389 LOC108238424 LOC108238424 ENSKMAP00000011747 ENSKMAP00000011747 LOC108231094 LOC108231094 LOC108231196 LOC108231196 polr2h polr2h LOC108251739 LOC108251739 LOC108236626 LOC108236626 LOC108235005 LOC108235005 fgf2 fgf2 LOC108240034 LOC108240034 LOC108239717 LOC108239717 LOC108248672 LOC108248672 ENSKMAP00000009317 ENSKMAP00000009317 fgf16 fgf16 fndc3b fndc3b LOC108240579 LOC108240579 LOC108244603 LOC108244603 LOC108230595 LOC108230595 POLR2E POLR2E kl kl LOC108240607 LOC108240607 CSDE1 CSDE1 FGFRL1 FGFRL1 fgf10 fgf10 Fgfbp2 Fgfbp2 uba52 uba52 fndc3a fndc3a esrp1 esrp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC108230630Heterogeneous nuclear ribonucleoprotein M. (690 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
hnrnpa1Uncharacterized protein. (336 aa)
LOC108241470Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
fgfr1Fibroblast growth factor receptor. (831 aa)
LOC108230049Lactase-like b; Belongs to the glycosyl hydrolase 1 family. (585 aa)
ENSKMAP00000025685Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (552 aa)
LOC108238084Fibroblast growth factor receptor 4. (945 aa)
LOC108237351Epithelial splicing regulatory protein 2. (742 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
ANOS1Anosmin 1. (679 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LOC108238085Uncharacterized protein. (881 aa)
LOC108246621Fibroblast growth factor binding protein 3. (237 aa)
LOC108239148Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
ENSKMAP00000022213Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (541 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1777 aa)
LOC108248915DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
SPRED2Sprouty related EVH1 domain containing 2. (477 aa)
ENSKMAP00000020331Sprouty RTK signaling antagonist 2. (329 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
LOC108237956Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
SRCTyrosine-protein kinase. (550 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (624 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (149 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (491 aa)
LOC108250029Lactase-like a; Belongs to the glycosyl hydrolase 1 family. (573 aa)
LOC108228343Sprouty related EVH1 domain containing 2a. (427 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (242 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
LOC108250222PH domain-containing protein. (704 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (530 aa)
LOC108240442General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (261 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (463 aa)
flrt2Fibronectin leucine rich transmembrane protein 2. (657 aa)
LOC108239982HRas proto-oncogene, GTPase a. (189 aa)
LOC108237634Tyrosine-protein kinase. (549 aa)
ENSKMAP00000003379SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
LOC108238827Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
rps27aRibosomal protein S27a. (156 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
LOC108248584Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
gab1GRB2-associated binding protein 1. (786 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
LOC108231882Fibronectin leucine rich transmembrane protein 2. (660 aa)
KRASGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108231354Fibronectin leucine rich transmembrane protein 1b. (727 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
LOC108236256Growth factor receptor-bound protein 2b. (224 aa)
LOC108239072Polypyrimidine tract binding protein 1a. (576 aa)
LOC108238369Anosmin 1b. (699 aa)
ubbUncharacterized protein. (270 aa)
LOC108235488Cbl proto-oncogene C, E3 ubiquitin protein ligase. (570 aa)
LOC108231995Polypeptide N-acetylgalactosaminyltransferase. (592 aa)
LOC108233785Fibronectin type-III domain-containing protein. (682 aa)
LOC108251146Uncharacterized protein. (386 aa)
PTBP2Polypyrimidine tract binding protein 2. (522 aa)
LOC108249920Fibroblast growth factor receptor. (701 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (189 aa)
spred1Sprouty related EVH1 domain containing 1. (445 aa)
fgfrl1Fibroblast growth factor receptor like 1a. (506 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (260 aa)
LOC108233283Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
Polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (177 aa)
frs2Fibroblast growth factor receptor substrate 2b. (532 aa)
LOC108232617Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC108243005Zgc:55558. (187 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (168 aa)
klbKlotho beta. (1024 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
LOC108239527Polypyrimidine tract binding protein 2b. (528 aa)
LOC108243526Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC108242980Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
fgfr2Fibroblast growth factor receptor. (835 aa)
LOC108242389Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC108238424Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSKMAP00000011747Fibroblast growth factor binding protein 1b. (198 aa)
LOC108231094Fibroblast growth factor receptor. (710 aa)
LOC108231196Fibroblast growth factor receptor substrate 3. (611 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
LOC108251739Polypyrimidine tract binding protein 3. (510 aa)
LOC108236626Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC108235005TIA1 cytotoxic granule-associated RNA binding protein. (386 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC108240034Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
LOC108239717Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
LOC108248672Polypyrimidine tract binding protein 1. (539 aa)
ENSKMAP00000009317STIL centriolar assembly protein. (855 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (253 aa)
fndc3bFibronectin type III domain containing 3Ba. (896 aa)
LOC108240579Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
LOC108244603Polypeptide N-acetylgalactosaminyltransferase. (620 aa)
LOC108230595Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
klKlotho. (981 aa)
LOC108240607Serine/threonine-protein phosphatase. (309 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (861 aa)
FGFRL1Fibroblast growth factor receptor like 1. (506 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
Fgfbp2Fibroblast growth factor binding protein 2b. (221 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
fndc3aFibronectin type III domain containing 3A. (1238 aa)
esrp1Epithelial splicing regulatory protein 1. (758 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
Server load: low (16%) [HD]