STRINGSTRING
LOC108249346 LOC108249346 LOC108247340 LOC108247340 ENSKMAP00000000483 ENSKMAP00000000483 ENSKMAP00000000575 ENSKMAP00000000575 pik3cb pik3cb ENSKMAP00000003379 ENSKMAP00000003379 LOC108248584 LOC108248584 PIK3CA PIK3CA mdk mdk LOC108250440 LOC108250440 jak3 jak3 HDAC3 HDAC3 LOC108237218 LOC108237218 ptpn6 ptpn6 LOC108238424 LOC108238424 ENSKMAP00000012342 ENSKMAP00000012342 ptn ptn ep300 ep300 LOC108233328 LOC108233328 LOC108233381 LOC108233381 prdm1 prdm1 plcg1 plcg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108249346PR domain containing 1b, with ZNF domain. (608 aa)
LOC108247340Protein tyrosine phosphatase receptor type Z1a. (1262 aa)
ENSKMAP00000000483Protein tyrosine phosphatase receptor type Z1b. (790 aa)
ENSKMAP00000000575Alpha-carbonic anhydrase domain-containing protein. (221 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
ENSKMAP00000003379SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
LOC108248584Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
mdkMidkine b. (142 aa)
LOC108250440E1A binding protein p300 a. (2399 aa)
jak3Tyrosine-protein kinase. (1112 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
LOC108237218Tyrosine-protein kinase receptor. (1477 aa)
ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
LOC108238424Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSKMAP00000012342Tyrosine-protein kinase receptor. (507 aa)
ptnPleiotrophin. (169 aa)
ep300E1A binding protein p300 b. (2785 aa)
LOC108233328MYCN proto-oncogene, bHLH transcription factor. (465 aa)
LOC108233381Uncharacterized protein. (781 aa)
prdm1PR domain containing 1a, with ZNF domain. (835 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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