20 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
	rpa2	RPA_C domain-containing protein. (274 aa)
	exo1	Exonuclease 1. (769 aa)
	rpa3	Replication protein A 14kDa subunit. (122 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
	lig1	DNA ligase. (1010 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	msh3	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (972 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
	ENSKMAP00000005281	Uncharacterized protein. (165 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
	ENSKMAP00000009313	Methionine sulfoxide reductase B1b. (467 aa)
	LOC108248126	RPA_C domain-containing protein. (199 aa)
	pold4	Uncharacterized protein. (110 aa)
	LOC108229664	PMS1 homolog 1, mismatch repair system component. (568 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (857 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa)
	pold1	DNA polymerase. (1105 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000005281	ENSKMAP00000009313	ENSKMAP00000005281	ENSKMAP00000009313	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.426
ENSKMAP00000005281	LOC108229664	ENSKMAP00000005281	ENSKMAP00000010478	Uncharacterized protein.	PMS1 homolog 1, mismatch repair system component.	0.933
ENSKMAP00000005281	RPA1	ENSKMAP00000005281	ENSKMAP00000000242	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.426
ENSKMAP00000005281	exo1	ENSKMAP00000005281	ENSKMAP00000017920	Uncharacterized protein.	Exonuclease 1.	0.880
ENSKMAP00000005281	mlh1	ENSKMAP00000005281	ENSKMAP00000011476	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.975
ENSKMAP00000005281	msh2	ENSKMAP00000005281	ENSKMAP00000015699	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.980
ENSKMAP00000005281	msh3	ENSKMAP00000005281	ENSKMAP00000003197	Uncharacterized protein.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.953
ENSKMAP00000005281	msh6	ENSKMAP00000005281	ENSKMAP00000022133	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.971
ENSKMAP00000005281	pcna	ENSKMAP00000005281	ENSKMAP00000003800	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.830
ENSKMAP00000005281	pms2	ENSKMAP00000005281	ENSKMAP00000011431	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.745
ENSKMAP00000005281	pold1	ENSKMAP00000005281	ENSKMAP00000013397	Uncharacterized protein.	DNA polymerase.	0.592
ENSKMAP00000005281	rpa1	ENSKMAP00000005281	ENSKMAP00000007505	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.426
ENSKMAP00000005281	rpa3	ENSKMAP00000005281	ENSKMAP00000019992	Uncharacterized protein.	Replication protein A 14kDa subunit.	0.506
ENSKMAP00000009313	ENSKMAP00000005281	ENSKMAP00000009313	ENSKMAP00000005281	Methionine sulfoxide reductase B1b.	Uncharacterized protein.	0.426
ENSKMAP00000009313	LOC108229664	ENSKMAP00000009313	ENSKMAP00000010478	Methionine sulfoxide reductase B1b.	PMS1 homolog 1, mismatch repair system component.	0.426
ENSKMAP00000009313	LOC108248126	ENSKMAP00000009313	ENSKMAP00000010056	Methionine sulfoxide reductase B1b.	RPA_C domain-containing protein.	0.789
ENSKMAP00000009313	exo1	ENSKMAP00000009313	ENSKMAP00000017920	Methionine sulfoxide reductase B1b.	Exonuclease 1.	0.767
ENSKMAP00000009313	lig1	ENSKMAP00000009313	ENSKMAP00000022977	Methionine sulfoxide reductase B1b.	DNA ligase.	0.647
ENSKMAP00000009313	mlh1	ENSKMAP00000009313	ENSKMAP00000011476	Methionine sulfoxide reductase B1b.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.611
ENSKMAP00000009313	msh2	ENSKMAP00000009313	ENSKMAP00000015699	Methionine sulfoxide reductase B1b.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.756