STRINGSTRING
LOC108236626 LOC108236626 FGF6 FGF6 LOC108241470 LOC108241470 plcg1 plcg1 LOC108239148 LOC108239148 LOC108237956 LOC108237956 fgf4 fgf4 fgf19 fgf19 LOC108236256 LOC108236256 fgf17 fgf17 fgf23 fgf23 LOC108233283 LOC108233283 frs2 frs2 LOC108243005 LOC108243005 fgf1 fgf1 LOC108242389 LOC108242389 LOC108238424 LOC108238424 LOC108231196 LOC108231196 fgf2 fgf2 LOC108240034 LOC108240034 fgf16 fgf16 LOC108240579 LOC108240579 CSDE1 CSDE1 PIK3CA PIK3CA KRAS KRAS gab1 gab1 LOC108248584 LOC108248584 LOC108238827 LOC108238827 ENSKMAP00000003379 ENSKMAP00000003379 LOC108239982 LOC108239982 LOC108250222 LOC108250222
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108236626Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC108241470Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
LOC108239148Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
LOC108237956Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
LOC108236256Growth factor receptor-bound protein 2b. (224 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (260 aa)
LOC108233283Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
frs2Fibroblast growth factor receptor substrate 2b. (532 aa)
LOC108243005Zgc:55558. (187 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (168 aa)
LOC108242389Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC108238424Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108231196Fibroblast growth factor receptor substrate 3. (611 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC108240034Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (253 aa)
LOC108240579Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (861 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KRASGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
gab1GRB2-associated binding protein 1. (786 aa)
LOC108248584Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC108238827Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
ENSKMAP00000003379SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
LOC108239982HRas proto-oncogene, GTPase a. (189 aa)
LOC108250222PH domain-containing protein. (704 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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