STRINGSTRING
LOC108238424 LOC108238424 LOC108242389 LOC108242389 fgfr2 fgfr2 LOC108242980 LOC108242980 LOC108243526 LOC108243526 LOC108239527 LOC108239527 ncbp2 ncbp2 fgf1 fgf1 mknk1 mknk1 polr2i polr2i LOC108240442 LOC108240442 gtf2f1 gtf2f1 LOC108250222 LOC108250222 LOC108230630 LOC108230630 LOC108243005 LOC108243005 LOC108232617 LOC108232617 frs2 frs2 Polr2d Polr2d LOC108233283 LOC108233283 fgf23 fgf23 polr2g polr2g ppp2cb ppp2cb fgf17 fgf17 PTBP2 PTBP2 LOC108251146 LOC108251146 LOC108235488 LOC108235488 ubb ubb LOC108239072 LOC108239072 LOC108236256 LOC108236256 fgf4 fgf4 fgf3 fgf3 mknk2 mknk2 polr2f polr2f polr2j polr2j SRC SRC LOC108237956 LOC108237956 cbl cbl ENSKMAP00000020331 ENSKMAP00000020331 polr2c polr2c LOC108248915 LOC108248915 polr2a polr2a LOC108239148 LOC108239148 LOC108246621 LOC108246621 LOC108238085 LOC108238085 polr2b polr2b plcg1 plcg1 LOC108237351 LOC108237351 ppp2ca ppp2ca LOC108241470 LOC108241470 hnrnpa1 hnrnpa1 FGF6 FGF6 LOC108239982 LOC108239982 gtf2f2 gtf2f2 LOC108237634 LOC108237634 ENSKMAP00000003379 ENSKMAP00000003379 LOC108238827 LOC108238827 rps27a rps27a polr2l polr2l fgf5 fgf5 NCBP1 NCBP1 LOC108248584 LOC108248584 gab1 gab1 fgf7 fgf7 KRAS KRAS PIK3CA PIK3CA LOC108230595 LOC108230595 mapk1 mapk1 esrp1 esrp1 fndc3a fndc3a uba52 uba52 Fgfbp2 Fgfbp2 fgf10 fgf10 CSDE1 CSDE1 LOC108240607 LOC108240607 POLR2E POLR2E LOC108240579 LOC108240579 fndc3b fndc3b fgf16 fgf16 LOC108248672 LOC108248672 LOC108239717 LOC108239717 LOC108240034 LOC108240034 fgf2 fgf2 LOC108235005 LOC108235005 LOC108236626 LOC108236626 LOC108251739 LOC108251739 polr2h polr2h LOC108231196 LOC108231196 ENSKMAP00000011747 ENSKMAP00000011747
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108238424Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108242389Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
fgfr2Fibroblast growth factor receptor. (835 aa)
LOC108242980Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
LOC108243526Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC108239527Polypyrimidine tract binding protein 2b. (528 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (168 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (463 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
LOC108240442General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (261 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (530 aa)
LOC108250222PH domain-containing protein. (704 aa)
LOC108230630Heterogeneous nuclear ribonucleoprotein M. (690 aa)
LOC108243005Zgc:55558. (187 aa)
LOC108232617Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
frs2Fibroblast growth factor receptor substrate 2b. (532 aa)
Polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (177 aa)
LOC108233283Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (260 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (189 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
PTBP2Polypyrimidine tract binding protein 2. (522 aa)
LOC108251146Uncharacterized protein. (386 aa)
LOC108235488Cbl proto-oncogene C, E3 ubiquitin protein ligase. (570 aa)
ubbUncharacterized protein. (270 aa)
LOC108239072Polypyrimidine tract binding protein 1a. (576 aa)
LOC108236256Growth factor receptor-bound protein 2b. (224 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (242 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (491 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (149 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC108237956Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
ENSKMAP00000020331Sprouty RTK signaling antagonist 2. (329 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
LOC108248915DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1777 aa)
LOC108239148Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
LOC108246621Fibroblast growth factor binding protein 3. (237 aa)
LOC108238085Uncharacterized protein. (881 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
LOC108237351Epithelial splicing regulatory protein 2. (742 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC108241470Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
hnrnpa1Uncharacterized protein. (336 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC108239982HRas proto-oncogene, GTPase a. (189 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
LOC108237634Tyrosine-protein kinase. (549 aa)
ENSKMAP00000003379SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
LOC108238827Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
rps27aRibosomal protein S27a. (156 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
LOC108248584Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
gab1GRB2-associated binding protein 1. (786 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
KRASGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108230595Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
esrp1Epithelial splicing regulatory protein 1. (758 aa)
fndc3aFibronectin type III domain containing 3A. (1238 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
Fgfbp2Fibroblast growth factor binding protein 2b. (221 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (861 aa)
LOC108240607Serine/threonine-protein phosphatase. (309 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
LOC108240579Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
fndc3bFibronectin type III domain containing 3Ba. (896 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (253 aa)
LOC108248672Polypyrimidine tract binding protein 1. (539 aa)
LOC108239717Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
LOC108240034Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC108235005TIA1 cytotoxic granule-associated RNA binding protein. (386 aa)
LOC108236626Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC108251739Polypyrimidine tract binding protein 3. (510 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
LOC108231196Fibroblast growth factor receptor substrate 3. (611 aa)
ENSKMAP00000011747Fibroblast growth factor binding protein 1b. (198 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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