51 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (260 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
	LOC108248584	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	gab1	GRB2-associated binding protein 1. (786 aa)
	KRAS	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1238 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (861 aa)
	LOC108240607	Serine/threonine-protein phosphatase. (309 aa)
	LOC108244603	Polypeptide N-acetylgalactosaminyltransferase. (620 aa)
	LOC108240579	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (896 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (253 aa)
	LOC108240034	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	LOC108236626	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC108231196	Fibroblast growth factor receptor substrate 3. (611 aa)
	LOC108238424	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC108242389	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC108242980	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
	LOC108243526	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (168 aa)
	LOC108243005	Zgc:55558. (187 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (532 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	fgf17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	LOC108231995	Polypeptide N-acetylgalactosaminyltransferase. (592 aa)
	LOC108235488	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (570 aa)
	ubb	Uncharacterized protein. (270 aa)
	LOC108236256	Growth factor receptor-bound protein 2b. (224 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (491 aa)
	GALNT3	Polypeptide N-acetylgalactosaminyltransferase. (624 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	LOC108237956	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	ENSKMAP00000020331	Sprouty RTK signaling antagonist 2. (329 aa)
	LOC108239148	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
	LOC108238085	Uncharacterized protein. (881 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC108241470	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	LOC108250222	PH domain-containing protein. (704 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (463 aa)
	LOC108239982	HRas proto-oncogene, GTPase a. (189 aa)
	LOC108237634	Tyrosine-protein kinase. (549 aa)
	ENSKMAP00000003379	SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
	LOC108238827	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
	rps27a	Ribosomal protein S27a. (156 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSKMAP00000003379	ENSKMAP00000007641	ENSKMAP00000003379	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.436
CSDE1	LOC108231196	ENSKMAP00000007641	ENSKMAP00000011249	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 3.	0.431
CSDE1	LOC108236256	ENSKMAP00000007641	ENSKMAP00000017060	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.678
CSDE1	LOC108236626	ENSKMAP00000007641	ENSKMAP00000011044	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.458
CSDE1	LOC108237634	ENSKMAP00000007641	ENSKMAP00000002899	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.428
CSDE1	LOC108238424	ENSKMAP00000007641	ENSKMAP00000011820	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
CSDE1	LOC108239148	ENSKMAP00000007641	ENSKMAP00000023606	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.436
CSDE1	LOC108242389	ENSKMAP00000007641	ENSKMAP00000012373	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.458
CSDE1	LOC108242980	ENSKMAP00000007641	ENSKMAP00000012530	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
CSDE1	LOC108243526	ENSKMAP00000007641	ENSKMAP00000012558	Cold shock domain containing E1, RNA-binding.	Protein phosphatase 2, regulatory subunit A, beta b.	0.435
CSDE1	LOC108248584	ENSKMAP00000007641	ENSKMAP00000004760	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.518
CSDE1	PIK3CA	ENSKMAP00000007641	ENSKMAP00000005670	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
CSDE1	SRC	ENSKMAP00000007641	ENSKMAP00000019871	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.428
CSDE1	fgf17	ENSKMAP00000007641	ENSKMAP00000015006	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.429
CSDE1	fgf23	ENSKMAP00000007641	ENSKMAP00000014430	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.438
CSDE1	fgf5	ENSKMAP00000007641	ENSKMAP00000004576	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.419
CSDE1	frs2	ENSKMAP00000007641	ENSKMAP00000013799	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 2b.	0.431
CSDE1	mapk1	ENSKMAP00000007641	ENSKMAP00000005892	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
CSDE1	rps27a	ENSKMAP00000007641	ENSKMAP00000004139	Cold shock domain containing E1, RNA-binding.	Ribosomal protein S27a.	0.494
CSDE1	uba52	ENSKMAP00000007641	ENSKMAP00000006381	Cold shock domain containing E1, RNA-binding.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.509