47 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	blm	BLM RecQ like helicase. (1384 aa)
	DNA2	DNA replication helicase/nuclease 2. (1388 aa)
	rmi1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa)
	tdrd3	Tudor domain containing 3. (787 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	ENSKMAP00000000467	TAN domain-containing protein. (123 aa)
	Atm	Uncharacterized protein. (130 aa)
	ENSKMAP00000001053	Uncharacterized protein. (109 aa)
	ankrd11	Ankyrin repeat domain 11. (2822 aa)
	rfc5	Replication factor C (activator 1) 5. (339 aa)
	CDCA7L	zf-4CXXC_R1 domain-containing protein. (406 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	nbn	Nibrin. (832 aa)
	slf1	SMC5-SMC6 complex localization factor 1. (879 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	ENSKMAP00000009313	Methionine sulfoxide reductase B1b. (467 aa)
	Rad9b	RAD9 checkpoint clamp component B. (194 aa)
	LOC108248126	RPA_C domain-containing protein. (199 aa)
	rfc2	Replication factor C (activator 1) 2. (357 aa)
	kat5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (574 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa)
	recql4	RecQ helicase-like 4. (1281 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	rad52	RAD52 homolog, DNA repair protein. (382 aa)
	LOC108244139	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
	rfc4	Replication factor C (activator 1) 4. (388 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
	rhno1	Si:ch73-352p4.5. (290 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa)
	rpa2	RPA_C domain-containing protein. (274 aa)
	exo1	Exonuclease 1. (769 aa)
	rad1	RAD1 homolog (S. pombe). (280 aa)
	rpa3	Replication protein A 14kDa subunit. (122 aa)
	top3a	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa)
	cdca7	Cell division cycle associated 7a. (404 aa)
	atrip	Uncharacterized protein. (776 aa)
	exd2	Exonuclease 3'-5' domain containing 2. (639 aa)
	topbp1	DNA topoisomerase II binding protein 1. (1510 aa)
	rad17	RAD17 checkpoint clamp loader component. (528 aa)
	abl1	Tyrosine-protein kinase. (1121 aa)
	Rbbp8	SAE2 domain-containing protein. (82 aa)
	brca1	Uncharacterized protein. (1354 aa)
	rmi2	RecQ mediated genome instability 2. (145 aa)
	ankrd12	Ankyrin repeat domain 12. (1924 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	CDCA7L	ENSKMAP00000000507	ENSKMAP00000002177	Uncharacterized protein.	zf-4CXXC_R1 domain-containing protein.	0.730
Atm	DNA2	ENSKMAP00000000507	ENSKMAP00000027709	Uncharacterized protein.	DNA replication helicase/nuclease 2.	0.872
Atm	ENSKMAP00000000467	ENSKMAP00000000507	ENSKMAP00000000467	Uncharacterized protein.	TAN domain-containing protein.	0.926
Atm	ENSKMAP00000001053	ENSKMAP00000000507	ENSKMAP00000001053	Uncharacterized protein.	Uncharacterized protein.	0.996
Atm	ENSKMAP00000009313	ENSKMAP00000000507	ENSKMAP00000009313	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.696
Atm	LOC108248126	ENSKMAP00000000507	ENSKMAP00000010056	Uncharacterized protein.	RPA_C domain-containing protein.	0.590
Atm	RPA1	ENSKMAP00000000507	ENSKMAP00000000242	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.752
Atm	Rad9b	ENSKMAP00000000507	ENSKMAP00000009721	Uncharacterized protein.	RAD9 checkpoint clamp component B.	0.807
Atm	Rbbp8	ENSKMAP00000000507	ENSKMAP00000023764	Uncharacterized protein.	SAE2 domain-containing protein.	0.820
Atm	abl1	ENSKMAP00000000507	ENSKMAP00000023528	Uncharacterized protein.	Tyrosine-protein kinase.	0.763
Atm	ankrd11	ENSKMAP00000000507	ENSKMAP00000001827	Uncharacterized protein.	Ankyrin repeat domain 11.	0.504
Atm	ankrd12	ENSKMAP00000000507	ENSKMAP00000027120	Uncharacterized protein.	Ankyrin repeat domain 12.	0.504
Atm	atrip	ENSKMAP00000000507	ENSKMAP00000027428	Uncharacterized protein.	Uncharacterized protein.	0.809
Atm	blm	ENSKMAP00000000507	ENSKMAP00000022385	Uncharacterized protein.	BLM RecQ like helicase.	0.875
Atm	brca1	ENSKMAP00000000507	ENSKMAP00000024393	Uncharacterized protein.	Uncharacterized protein.	0.991
Atm	cdca7	ENSKMAP00000000507	ENSKMAP00000020885	Uncharacterized protein.	Cell division cycle associated 7a.	0.730
Atm	exd2	ENSKMAP00000000507	ENSKMAP00000022601	Uncharacterized protein.	Exonuclease 3'-5' domain containing 2.	0.704
Atm	exo1	ENSKMAP00000000507	ENSKMAP00000017920	Uncharacterized protein.	Exonuclease 1.	0.890
Atm	hus1	ENSKMAP00000000507	ENSKMAP00000013619	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.783
Atm	kat5	ENSKMAP00000000507	ENSKMAP00000011979	Uncharacterized protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.707