STRINGSTRING
LOC108251554 LOC108251554 rfc1 rfc1 RPA1 RPA1 cul4b cul4b YY1 YY1 ino80b ino80b LOC108245429 LOC108245429 cops3 cops3 LOC108242722 LOC108242722 gtf2h4 gtf2h4 rfc5 rfc5 RCBTB1 RCBTB1 ddb1 ddb1 xpc xpc usp45 usp45 pold2 pold2 pcna pcna rps27a rps27a cops2 cops2 sumo1 sumo1 ENSKMAP00000005692 ENSKMAP00000005692 ube2n ube2n rcbtb2 rcbtb2 tfpt tfpt uba52 uba52 vwa5b2 vwa5b2 ube2v2 ube2v2 ccnh ccnh ino80c ino80c rpa1 rpa1 rfc3 rfc3 kxd1 kxd1 mnat1 mnat1 LOC108236794 LOC108236794 ENSKMAP00000009313 ENSKMAP00000009313 rnf111 rnf111 LOC108248126 LOC108248126 rpap3 rpap3 pold4 pold4 cops8 cops8 cops5 cops5 LOC108236604 LOC108236604 rfc2 rfc2 LOC108244554 LOC108244554 gtf2h5 gtf2h5 cops7a cops7a rad23a rad23a pole3 pole3 ino80e ino80e cops4 cops4 pold1 pold1 pole2 pole2 LOC108245850 LOC108245850 LOC108244139 LOC108244139 actr8 actr8 rfc4 rfc4 parp1 parp1 LOC108237844 LOC108237844 LOC108232577 LOC108232577 polk polk ube2i ube2i actr5 actr5 ubb ubb LOC108240719 LOC108240719 LOC108250655 LOC108250655 cdk7 cdk7 rpa2 rpa2 LOC108235081 LOC108235081 chd1l chd1l rpa3 rpa3 rbx1 rbx1 RAD23B RAD23B bivm bivm Pole Pole gps1 gps1 ENSKMAP00000020750 ENSKMAP00000020750 actb actb LOC108236207 LOC108236207 ino80d ino80d mcrs1 mcrs1 pold3 pold3 wdr76 wdr76 parp2 parp2 cetn3 cetn3 COPS6 COPS6 ino80 ino80 gtf2h3 gtf2h3 ruvbl1 ruvbl1 LOC108229849 LOC108229849 ddb2 ddb2 ercc1 ercc1 parp3 parp3 xpa xpa sumo2 sumo2 gtf2h1 gtf2h1 ENSKMAP00000028503 ENSKMAP00000028503 atad5 atad5 ercc2 ercc2 ercc3 ercc3 ercc4 ercc4 LOC108232507 LOC108232507 LOC108229807 LOC108229807 ercc5 ercc5 nfrkb nfrkb pole4 pole4 LOC108230590 LOC108230590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108251554Si:ch73-290k24.6. (783 aa)
rfc1Replication factor C subunit 1. (1180 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
cul4bCullin 4B; Belongs to the cullin family. (869 aa)
YY1YY1 transcription factor b. (368 aa)
ino80bINO80 complex subunit B. (335 aa)
LOC108245429Uncharacterized protein. (484 aa)
cops3COP9 signalosome subunit 3. (423 aa)
LOC108242722Small ubiquitin-related modifier. (96 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
rfc5Replication factor C (activator 1) 5. (339 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
ddb1Damage-specific DNA binding protein 1. (1075 aa)
xpcXeroderma pigmentosum, complementation group C. (935 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (868 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rps27aRibosomal protein S27a. (156 aa)
cops2COP9 signalosome subunit 2. (443 aa)
sumo1Small ubiquitin-related modifier. (105 aa)
ENSKMAP00000005692Rad60-SLD domain-containing protein. (139 aa)
ube2nUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
tfptTCF3 (E2A) fusion partner. (197 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
vwa5b2Von Willebrand factor A domain containing 5B2. (1143 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
ccnhCyclin H; Belongs to the cyclin family. (333 aa)
ino80cINO80 complex subunit C. (207 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
kxd1KxDL motif containing 1. (185 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
LOC108236794YY1 transcription factor. (346 aa)
ENSKMAP00000009313Methionine sulfoxide reductase B1b. (467 aa)
rnf111Ring finger protein 111. (1023 aa)
LOC108248126RPA_C domain-containing protein. (199 aa)
rpap3RNA polymerase II associated protein 3. (650 aa)
pold4Uncharacterized protein. (110 aa)
cops8COP9 signalosome subunit 8. (191 aa)
cops5COP9 signalosome subunit 5. (334 aa)
LOC108236604Centrin 4. (173 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
LOC108244554Uncharacterized protein. (375 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (365 aa)
pole3CBFD_NFYB_HMF domain-containing protein. (153 aa)
ino80eINO80 complex subunit E. (250 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
pold1DNA polymerase. (1105 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
LOC108245850Uncharacterized protein. (375 aa)
LOC108244139Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (643 aa)
rfc4Replication factor C (activator 1) 4. (388 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
LOC108237844Protein inhibitor of activated STAT, 1a. (698 aa)
LOC108232577Small ubiquitin-related modifier. (94 aa)
polkPolymerase (DNA directed) kappa. (401 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
actr5Actin related protein 5; Belongs to the actin family. (642 aa)
ubbUncharacterized protein. (270 aa)
LOC108240719Small ubiquitin-related modifier. (94 aa)
LOC108250655Potassium channel tetramerization domain containing 2. (265 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
rpa2RPA_C domain-containing protein. (274 aa)
LOC108235081UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (1014 aa)
rpa3Replication protein A 14kDa subunit. (122 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (396 aa)
bivmBasic, immunoglobulin-like variable motif containing. (481 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (298 aa)
gps1G protein pathway suppressor 1. (487 aa)
ENSKMAP00000020750DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (314 aa)
actbUncharacterized protein. (375 aa)
LOC108236207UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ino80dINO80 complex subunit Da. (1000 aa)
mcrs1Microspherule protein 1. (466 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (575 aa)
parp2Poly [ADP-ribose] polymerase. (655 aa)
cetn3Centrin 3. (172 aa)
COPS6COP9 signalosome subunit 6. (316 aa)
ino80INO80 complex ATPase subunit. (1474 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (299 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC108229849Protein inhibitor of activated STAT, 1b. (648 aa)
ddb2Damage-specific DNA binding protein 2. (497 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
parp3Poly [ADP-ribose] polymerase. (530 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (409 aa)
ENSKMAP00000028503PH_TFIIH domain-containing protein. (131 aa)
atad5ATPase family AAA domain containing 5a. (1804 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
LOC108232507General transcription factor IIH subunit. (392 aa)
LOC108229807Cullin 4A; Belongs to the cullin family. (746 aa)
ercc5Excision repair cross-complementation group 5. (1028 aa)
nfrkbNuclear factor related to kappaB binding protein. (1278 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
LOC108230590SCY domain-containing protein. (122 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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