42 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC108239622	NTF2 domain-containing protein. (130 aa)
	proser1	Proline and serine rich 1. (787 aa)
	ENSKMAP00000009313	Methionine sulfoxide reductase B1b. (467 aa)
	LOC108231373	Centromere protein S. (158 aa)
	kxd1	KxDL motif containing 1. (185 aa)
	LOC108242278	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
	dclre1b	DNA cross-link repair 1B. (573 aa)
	fanci	FA complementation group I. (1317 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	mus81	MUS81 structure-specific endonuclease subunit. (556 aa)
	LOC108246201	Essential meiotic structure-specific endonuclease 1. (533 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	ENSKMAP00000001053	Uncharacterized protein. (109 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	fan1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (969 aa)
	fancf	FA complementation group F. (335 aa)
	nutf2	Nuclear transport factor 2. (127 aa)
	fancd2	FA complementation group D2. (1361 aa)
	atrip	Uncharacterized protein. (776 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	ube2t	Ubiquitin-conjugating enzyme E2T (putative). (194 aa)
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa)
	wdr48	WD repeat domain 48b. (677 aa)
	dclre1a	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (907 aa)
	fancl	FA complementation group L. (371 aa)
	fancb	FA complementation group B. (776 aa)
	fanca	Fanconi_A_N domain-containing protein. (1475 aa)
	rpa3	Replication protein A 14kDa subunit. (122 aa)
	faap24	FA core complex associated protein 24. (202 aa)
	ENSKMAP00000018989	Uncharacterized protein. (152 aa)
	EME2	ERCC4 domain-containing protein. (416 aa)
	fancg	FA complementation group G. (600 aa)
	rpa2	RPA_C domain-containing protein. (274 aa)
	ubb	Uncharacterized protein. (270 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (787 aa)
	cenpx	Centromere protein X. (81 aa)
	ENSKMAP00000012494	Helicase ATP-binding domain-containing protein. (418 aa)
	fancm	Helicase C-terminal domain-containing protein. (1616 aa)
	FAAP100	FA core complex associated protein 100. (842 aa)
	LOC108248126	RPA_C domain-containing protein. (199 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EME2	ENSKMAP00000012494	ENSKMAP00000018337	ENSKMAP00000012494	ERCC4 domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.608
EME2	LOC108242278	ENSKMAP00000018337	ENSKMAP00000007581	ERCC4 domain-containing protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.463
EME2	LOC108246201	ENSKMAP00000018337	ENSKMAP00000002680	ERCC4 domain-containing protein.	Essential meiotic structure-specific endonuclease 1.	0.791
EME2	dclre1a	ENSKMAP00000018337	ENSKMAP00000025227	ERCC4 domain-containing protein.	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae).	0.406
EME2	ercc1	ENSKMAP00000018337	ENSKMAP00000027419	ERCC4 domain-containing protein.	Excision repair cross-complementation group 1.	0.409
EME2	ercc4	ENSKMAP00000018337	ENSKMAP00000029520	ERCC4 domain-containing protein.	Excision repair cross-complementation group 4.	0.673
EME2	faap24	ENSKMAP00000018337	ENSKMAP00000019785	ERCC4 domain-containing protein.	FA core complex associated protein 24.	0.618
EME2	fancm	ENSKMAP00000018337	ENSKMAP00000012450	ERCC4 domain-containing protein.	Helicase C-terminal domain-containing protein.	0.608
EME2	mus81	ENSKMAP00000018337	ENSKMAP00000003400	ERCC4 domain-containing protein.	MUS81 structure-specific endonuclease subunit.	0.988
EME2	rps27a	ENSKMAP00000018337	ENSKMAP00000004139	ERCC4 domain-containing protein.	Ribosomal protein S27a.	0.506
EME2	slx4	ENSKMAP00000018337	ENSKMAP00000026597	ERCC4 domain-containing protein.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.589
EME2	uba52	ENSKMAP00000018337	ENSKMAP00000006381	ERCC4 domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.500
EME2	ubb	ENSKMAP00000018337	ENSKMAP00000016559	ERCC4 domain-containing protein.	Uncharacterized protein.	0.417
ENSKMAP00000001053	ENSKMAP00000009313	ENSKMAP00000001053	ENSKMAP00000009313	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.914
ENSKMAP00000001053	ENSKMAP00000012494	ENSKMAP00000001053	ENSKMAP00000012494	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.987
ENSKMAP00000001053	ENSKMAP00000018989	ENSKMAP00000001053	ENSKMAP00000018989	Uncharacterized protein.	Uncharacterized protein.	0.540
ENSKMAP00000001053	LOC108231373	ENSKMAP00000001053	ENSKMAP00000007954	Uncharacterized protein.	Centromere protein S.	0.613
ENSKMAP00000001053	LOC108239622	ENSKMAP00000001053	ENSKMAP00000009947	Uncharacterized protein.	NTF2 domain-containing protein.	0.521
ENSKMAP00000001053	LOC108242278	ENSKMAP00000001053	ENSKMAP00000007581	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.578
ENSKMAP00000001053	LOC108248126	ENSKMAP00000001053	ENSKMAP00000010056	Uncharacterized protein.	RPA_C domain-containing protein.	0.866