35 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gatad2a	GATA zinc finger domain containing 2Ab. (639 aa)
	ing1	Inhibitor of growth protein. (304 aa)
	chd3	Chromodomain helicase DNA binding protein 3. (1811 aa)
	LOC108242669	Chromodomain helicase DNA binding protein 4a. (1769 aa)
	chd5	Uncharacterized protein. (1779 aa)
	pip4p1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (270 aa)
	LOC108235623	Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (409 aa)
	pip4k2a	Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (404 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (412 aa)
	ep300	E1A binding protein p300 b. (2785 aa)
	LOC108232401	Retinoblastoma binding protein 4. (424 aa)
	brpf1	Uncharacterized protein. (1290 aa)
	brd9	Bromodomain containing 9. (660 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (372 aa)
	LOC108237907	Retinoblastoma binding protein 4, like. (440 aa)
	kat6a	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2266 aa)
	LOC108235376	Uncharacterized protein. (1969 aa)
	LOC108250440	E1A binding protein p300 a. (2399 aa)
	pip4p2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
	LOC108239526	Uncharacterized protein. (749 aa)
	ing2	Inhibitor of growth protein. (281 aa)
	LOC108250244	Uncharacterized protein. (1145 aa)
	brd7	Bromodomain containing 7. (620 aa)
	gatad2b	GATA zinc finger domain containing 2B. (658 aa)
	brd1	Bromodomain containing 1a. (1288 aa)
	LOC108244154	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	meaf6	MYST/Esa1-associated factor 6. (203 aa)
	pip4k2c	Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (412 aa)
	LOC108238174	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	LOC108248594	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (256 aa)
	ing5	Inhibitor of growth protein. (231 aa)
	LOC108246299	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC108231338	Bromodomain and PHD finger containing, 3a. (1231 aa)
	LOC108233112	Bromodomain and PHD finger containing, 3b. (1250 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108231338	LOC108250244	ENSKMAP00000006982	ENSKMAP00000000921	Bromodomain and PHD finger containing, 3a.	Uncharacterized protein.	0.540
LOC108231338	LOC108250440	ENSKMAP00000006982	ENSKMAP00000008734	Bromodomain and PHD finger containing, 3a.	E1A binding protein p300 a.	0.410
LOC108231338	TP53	ENSKMAP00000006982	ENSKMAP00000018969	Bromodomain and PHD finger containing, 3a.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.521
LOC108231338	brd1	ENSKMAP00000006982	ENSKMAP00000001380	Bromodomain and PHD finger containing, 3a.	Bromodomain containing 1a.	0.539
LOC108231338	brd7	ENSKMAP00000006982	ENSKMAP00000001261	Bromodomain and PHD finger containing, 3a.	Bromodomain containing 7.	0.575
LOC108231338	brd9	ENSKMAP00000006982	ENSKMAP00000018991	Bromodomain and PHD finger containing, 3a.	Bromodomain containing 9.	0.605
LOC108231338	brpf1	ENSKMAP00000006982	ENSKMAP00000019902	Bromodomain and PHD finger containing, 3a.	Uncharacterized protein.	0.539
LOC108231338	ep300	ENSKMAP00000006982	ENSKMAP00000020640	Bromodomain and PHD finger containing, 3a.	E1A binding protein p300 b.	0.410
LOC108231338	ing1	ENSKMAP00000006982	ENSKMAP00000029816	Bromodomain and PHD finger containing, 3a.	Inhibitor of growth protein.	0.549
LOC108231338	ing2	ENSKMAP00000006982	ENSKMAP00000007520	Bromodomain and PHD finger containing, 3a.	Inhibitor of growth protein.	0.567
LOC108231338	ing5	ENSKMAP00000006982	ENSKMAP00000005673	Bromodomain and PHD finger containing, 3a.	Inhibitor of growth protein.	0.722
LOC108231338	kat6a	ENSKMAP00000006982	ENSKMAP00000011679	Bromodomain and PHD finger containing, 3a.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.675
LOC108231338	meaf6	ENSKMAP00000006982	ENSKMAP00000003977	Bromodomain and PHD finger containing, 3a.	MYST/Esa1-associated factor 6.	0.872
LOC108232401	LOC108235376	ENSKMAP00000019969	ENSKMAP00000010565	Retinoblastoma binding protein 4.	Uncharacterized protein.	0.805
LOC108232401	LOC108239526	ENSKMAP00000019969	ENSKMAP00000007794	Retinoblastoma binding protein 4.	Uncharacterized protein.	0.798
LOC108232401	LOC108242669	ENSKMAP00000019969	ENSKMAP00000026097	Retinoblastoma binding protein 4.	Chromodomain helicase DNA binding protein 4a.	0.805
LOC108232401	LOC108250440	ENSKMAP00000019969	ENSKMAP00000008734	Retinoblastoma binding protein 4.	E1A binding protein p300 a.	0.402
LOC108232401	brd7	ENSKMAP00000019969	ENSKMAP00000001261	Retinoblastoma binding protein 4.	Bromodomain containing 7.	0.446
LOC108232401	brd9	ENSKMAP00000019969	ENSKMAP00000018991	Retinoblastoma binding protein 4.	Bromodomain containing 9.	0.439
LOC108232401	chd3	ENSKMAP00000019969	ENSKMAP00000026230	Retinoblastoma binding protein 4.	Chromodomain helicase DNA binding protein 3.	0.805