STRINGSTRING
prim2 prim2 DNA2 DNA2 atad5 atad5 pola2 pola2 lig1 lig1 pold3 pold3 pola1 pola1 rpa3 rpa3 rpa2 rpa2 prim1 prim1 rfc4 rfc4 LOC108244139 LOC108244139 gins2 gins2 pold1 pold1 rfc2 rfc2 pold4 pold4 LOC108248126 LOC108248126 ENSKMAP00000009313 ENSKMAP00000009313 gins3 gins3 rfc3 rfc3 rpa1 rpa1 gins4 gins4 fen1 fen1 rcbtb2 rcbtb2 LOC108244487 LOC108244487 pcna pcna pold2 pold2 gins1 gins1 RCBTB1 RCBTB1 rfc5 rfc5 RPA1 RPA1 rfc1 rfc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (516 aa)
DNA2DNA replication helicase/nuclease 2. (1388 aa)
atad5ATPase family AAA domain containing 5a. (1804 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
lig1DNA ligase. (1010 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
pola1DNA polymerase. (1476 aa)
rpa3Replication protein A 14kDa subunit. (122 aa)
rpa2RPA_C domain-containing protein. (274 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (427 aa)
rfc4Replication factor C (activator 1) 4. (388 aa)
LOC108244139Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (207 aa)
pold1DNA polymerase. (1105 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
pold4Uncharacterized protein. (110 aa)
LOC108248126RPA_C domain-containing protein. (199 aa)
ENSKMAP00000009313Methionine sulfoxide reductase B1b. (467 aa)
gins3GINS complex subunit 3. (211 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
rcbtb2Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
LOC108244487Zgc:110269. (346 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
rfc5Replication factor C (activator 1) 5. (339 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rfc1Replication factor C subunit 1. (1180 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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