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| | abraxas1 | Abraxas 1, BRCA1 A complex subunit. (349 aa) |
| | LOC108246065 | Cell division cycle 25B. (528 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | ENSKMAP00000022564 | Histone H2B; Belongs to the histone H2B family. (168 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1510 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (528 aa) |
| | ENSKMAP00000028001 | Reverse transcriptase domain-containing protein. (874 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1388 aa) |
| | ENSKMAP00000027458 | Reverse transcriptase domain-containing protein. (1256 aa) |
| | atrip | Uncharacterized protein. (776 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | ENSKMAP00000023736 | Reverse transcriptase domain-containing protein. (885 aa) |
| | ENSKMAP00000023289 | Uncharacterized protein. (164 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | LOC108235081 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | ENSKMAP00000000467 | TAN domain-containing protein. (123 aa) |
| | Atm | Uncharacterized protein. (130 aa) |
| | ywhaz | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) |
| | ENSKMAP00000000943 | Uncharacterized protein. (144 aa) |
| | ENSKMAP00000001053 | Uncharacterized protein. (109 aa) |
| | ENSKMAP00000001130 | Reverse transcriptase domain-containing protein. (1110 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2822 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (339 aa) |
| | CDCA7L | zf-4CXXC_R1 domain-containing protein. (406 aa) |
| | ENSKMAP00000003442 | Reverse transcriptase domain-containing protein. (1237 aa) |
| | ENSKMAP00000003646 | Uncharacterized protein; Belongs to the histone H2B family. (148 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (507 aa) |
| | nbn | Nibrin. (832 aa) |
| | ENSKMAP00000004573 | Reverse transcriptase domain-containing protein. (1001 aa) |
| | LOC108229423 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | ube2n | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | LOC108241661 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | ENSKMAP00000006347 | Uncharacterized protein. (270 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC108248076 | Checkpoint kinase 2. (534 aa) |
| | ENSKMAP00000008060 | Reverse transcriptase domain-containing protein. (975 aa) |
| | ENSKMAP00000008309 | Reverse transcriptase domain-containing protein. (1265 aa) |
| | ENSKMAP00000008333 | annotation not available (990 aa) |
| | ENSKMAP00000008781 | Reverse transcriptase domain-containing protein. (1162 aa) |
| | LOC108237209 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (249 aa) |
| | ENSKMAP00000009231 | Reverse transcriptase domain-containing protein. (987 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1702 aa) |
| | LOC108240030 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC108240031 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | ENSKMAP00000009514 | Reverse transcriptase domain-containing protein. (489 aa) |
| | Rad9b | RAD9 checkpoint clamp component B. (194 aa) |
| | LOC108248126 | RPA_C domain-containing protein. (199 aa) |
| | LOC108247233 | Histone H4. (103 aa) |
| | LOC108241206 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (249 aa) |
| | ENSKMAP00000011321 | annotation not available (1265 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (397 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (574 aa) |
| | LOC108248151 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (257 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa) |
| | mdc1 | Uncharacterized protein. (1989 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | ENSKMAP00000012922 | Histone H2B; Belongs to the histone H2B family. (155 aa) |
| | LOC108229777 | Histone H4. (103 aa) |
| | ENSKMAP00000013203 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | LOC108236023 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | Brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (263 aa) |
| | nsd2 | Nuclear receptor binding SET domain protein 2. (1267 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (388 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | LOC108245856 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | rhno1 | Si:ch73-352p4.5. (290 aa) |
| | ENSKMAP00000017454 | Reverse transcriptase domain-containing protein. (1273 aa) |
| | rpa2 | RPA_C domain-containing protein. (274 aa) |
| | exo1 | Exonuclease 1. (769 aa) |
| | LOC108233911 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa) |
| | ENSKMAP00000018069 | Histone H2B; Belongs to the histone H2B family. (151 aa) |
| | uimc1 | Uncharacterized protein. (976 aa) |
| | ENSKMAP00000000423 | Reverse transcriptase domain-containing protein. (1066 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (372 aa) |
| | rad1 | RAD1 homolog (S. pombe). (280 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (381 aa) |
| | ENSKMAP00000019521 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | ENSKMAP00000019606 | Reverse transcriptase domain-containing protein. (1217 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | ENSKMAP00000020023 | annotation not available (828 aa) |
| | cdk1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa) |
| | ENSKMAP00000020216 | Reverse transcriptase domain-containing protein. (796 aa) |
| | LOC108246551 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa) |
| | ENSKMAP00000020407 | Reverse transcriptase domain-containing protein. (1258 aa) |
| | LOC108243642 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | ENSKMAP00000020635 | Uncharacterized protein. (178 aa) |
| | wee1 | Wee1-like protein kinase. (624 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | cdca7 | Cell division cycle associated 7a. (404 aa) |
| | ENSKMAP00000021337 | Reverse transcriptase domain-containing protein. (876 aa) |
| | ENSKMAP00000021513 | Reverse transcriptase domain-containing protein. (1156 aa) |
| | ENSKMAP00000021569 | Reverse transcriptase domain-containing protein. (1121 aa) |
| | ENSKMAP00000029997 | Reverse transcriptase domain-containing protein. (1252 aa) |
| | tdrd3 | Tudor domain containing 3. (787 aa) |
| | LOC108237560 | Wee1-like protein kinase. (546 aa) |
| | ENSKMAP00000028753 | Histone H2A; Belongs to the histone H2A family. (124 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1924 aa) |
| | rmi2 | RecQ mediated genome instability 2. (145 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (515 aa) |
| | ENSKMAP00000024731 | Uncharacterized protein. (235 aa) |
| | ENSKMAP00000024676 | Reverse transcriptase domain-containing protein. (1254 aa) |
| | ENSKMAP00000000178 | Reverse transcriptase domain-containing protein. (1096 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
