STRINGSTRING
LOC108238714 LOC108238714 LOC108250222 LOC108250222 LOC108248502 LOC108248502 LOC108244491 LOC108244491 LOC108250884 LOC108250884 pik3cb pik3cb LOC108237634 LOC108237634 ENSKMAP00000003379 ENSKMAP00000003379 LOC108248584 LOC108248584 gab1 gab1 gab2 gab2 PIK3CA PIK3CA fndc3a fndc3a LOC108238336 LOC108238336 LOC108234365 LOC108234365 LOC108248084 LOC108248084 fndc3b fndc3b LOC108242850 LOC108242850 dok6 dok6 gdnf gdnf LOC108236435 LOC108236435 LOC108250477 LOC108250477 ret ret shank1 shank1 LOC108238424 LOC108238424 LOC108247545 LOC108247545 frs2 frs2 prkacb prkacb LOC108247561 LOC108247561 LOC108245882 LOC108245882 LOC108237215 LOC108237215 dok4 dok4 PSPN PSPN shank3 shank3 LOC108248805 LOC108248805 LOC108236256 LOC108236256 LOC108241350 LOC108241350 GRB14 GRB14 SRC SRC SHC3 SHC3 LOC108239664 LOC108239664 LOC108247693 LOC108247693 LOC108244850 LOC108244850 mapk7 mapk7 pik3cd pik3cd LOC108242531 LOC108242531 plcg1 plcg1 gfra1 gfra1 prkaca prkaca pdlim7 pdlim7 LOC108248979 LOC108248979 LOC108231145 LOC108231145 pdlim5 pdlim5 LOC108232318 LOC108232318 LOC108232825 LOC108232825 irs2 irs2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108238714Growth factor receptor-bound protein 10a. (599 aa)
LOC108250222PH domain-containing protein. (704 aa)
LOC108248502Insulin receptor substrate 2a. (1038 aa)
LOC108244491TGF_BETA_2 domain-containing protein. (318 aa)
LOC108250884Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
LOC108237634Tyrosine-protein kinase. (549 aa)
ENSKMAP00000003379SHC (Src homology 2 domain containing) transforming protein 1. (340 aa)
LOC108248584Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
gab1GRB2-associated binding protein 1. (786 aa)
gab2GRB2-associated binding protein 2. (676 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
fndc3aFibronectin type III domain containing 3A. (1238 aa)
LOC108238336Uncharacterized protein. (470 aa)
LOC108234365Uncharacterized protein. (426 aa)
LOC108248084Docking protein 2. (613 aa)
fndc3bFibronectin type III domain containing 3Ba. (896 aa)
LOC108242850Docking protein 1b. (681 aa)
dok6Docking protein 6. (385 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (246 aa)
LOC108236435GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (458 aa)
LOC108250477Uncharacterized protein. (1558 aa)
retRet proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1200 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (2430 aa)
LOC108238424Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC108247545PDZ and LIM domain 5b. (609 aa)
frs2Fibroblast growth factor receptor substrate 2b. (532 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC108247561Uncharacterized protein. (456 aa)
LOC108245882Uncharacterized protein. (717 aa)
LOC108237215Uncharacterized protein. (1771 aa)
dok4Docking protein 4. (332 aa)
PSPNPersephin. (140 aa)
shank3SH3 and multiple ankyrin repeat domains 3a. (1987 aa)
LOC108248805Uncharacterized protein. (450 aa)
LOC108236256Growth factor receptor-bound protein 2b. (224 aa)
LOC108241350Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
GRB14Growth factor receptor bound protein 14. (524 aa)
SRCTyrosine-protein kinase. (550 aa)
SHC3SHC adaptor protein 3. (671 aa)
LOC108239664Uncharacterized protein; Belongs to the protein kinase superfamily. (349 aa)
LOC108247693GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (469 aa)
LOC108244850Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (723 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1108 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC108242531GDNF family receptor alpha 2b. (427 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
gfra1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (473 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
pdlim7PDZ and LIM domain 7. (434 aa)
LOC108248979Growth factor receptor bound protein 7. (518 aa)
LOC108231145GDNF family receptor alpha 4b. (430 aa)
pdlim5PDZ and LIM domain 5a. (571 aa)
LOC108232318Growth factor receptor-bound protein 10b. (618 aa)
LOC108232825Neurturin. (229 aa)
irs2Insulin receptor substrate 2b. (1136 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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