STRINGSTRING
mvd mvd hsd3b7 hsd3b7 LOC108232721 LOC108232721 LOC108245380 LOC108245380 ENSKMAP00000011512 ENSKMAP00000011512 plpp6 plpp6 tspo tspo LOC108234932 LOC108234932 LOC108246358 LOC108246358 hsdl2 hsdl2 srd5a2 srd5a2 ENSKMAP00000010114 ENSKMAP00000010114 ncoa2 ncoa2 LOC108231375 LOC108231375 ENSKMAP00000009203 ENSKMAP00000009203 LOC108233105 LOC108233105 LOC108244039 LOC108244039 LOC108230837 LOC108230837 mbtps1 mbtps1 hsd17b12 hsd17b12 LOC108238278 LOC108238278 acot8 acot8 LOC108251651 LOC108251651 LOC108248082 LOC108248082 LOC108245161 LOC108245161 srd5a3 srd5a3 LOC108250404 LOC108250404 LOC108231916 LOC108231916 scp2 scp2 msmo1 msmo1 LOC108229515 LOC108229515 HSD17B7 HSD17B7 LOC108238813 LOC108238813 LOC108251615 LOC108251615 LOC108232148 LOC108232148 LOC108250100 LOC108250100 ENSKMAP00000022691 ENSKMAP00000022691 LOC108232790 LOC108232790 LOC108229945 LOC108229945 LOC108235620 LOC108235620 rxra rxra LOC108241974 LOC108241974 hsdl1 hsdl1 arv1 arv1 LOC108236207 LOC108236207 osbpl6 osbpl6 LOC108243744 LOC108243744 sdr16c5 sdr16c5 mvk mvk LOC108242506 LOC108242506 PLPP7 PLPP7 ENSKMAP00000020812 ENSKMAP00000020812 ENSKMAP00000020705 ENSKMAP00000020705 LOC108245362 LOC108245362 ch25h ch25h LOC108247630 LOC108247630 LOC108250729 LOC108250729 LOC108231477 LOC108231477 LOC108243127 LOC108243127 LOC108242023 LOC108242023 pias4 pias4 LOC108251556 LOC108251556 LOC108233144 LOC108233144 LOC108231774 LOC108231774 LOC108236565 LOC108236565 ENSKMAP00000004088 ENSKMAP00000004088 LOC108236563 LOC108236563 LOC108229396 LOC108229396 ENSKMAP00000004016 ENSKMAP00000004016 SLCO1C1 SLCO1C1 LOC108247994 LOC108247994 star star LOC108231838 LOC108231838 LOC108231837 LOC108231837 LOC112450290 LOC112450290 fdxr fdxr sqle sqle fdps fdps LOC108250266 LOC108250266 rusc1 rusc1 kpnb1 kpnb1 LOC108242722 LOC108242722 LOC108247361 LOC108247361 LOC108248515 LOC108248515 ebpl ebpl sdr42e1 sdr42e1 SLC10A1 SLC10A1 hsd17b4 hsd17b4 dhrs7c dhrs7c LOC108239853 LOC108239853 LOC108247360 LOC108247360 srd5a1 srd5a1 LOC108240983 LOC108240983 scap scap stard3nl stard3nl osbpl9 osbpl9 cubn cubn LOC108250623 LOC108250623 CYP19A1 CYP19A1 mbtps2 mbtps2 akr1b1 akr1b1 LOC108240996 LOC108240996 LOC108243856 LOC108243856 LOC108237530 LOC108237530 Cdcp2 Cdcp2 ptgis ptgis LOC108238612 LOC108238612 LOC108238592 LOC108238592 FABP6-2 FABP6-2 sumo2 sumo2 stard5 stard5 ebp ebp stard3 stard3 LOC108233374 LOC108233374 LOC108233476 LOC108233476 srebf1 srebf1 LOC108247306 LOC108247306 nsdhl nsdhl adgrd1 adgrd1 hsd17b1 hsd17b1 FADS6 FADS6 fdx2 fdx2 LOC108229950 LOC108229950 LOC108241911 LOC108241911 LOC108237017 LOC108237017 faxdc2 faxdc2 LOC108234567 LOC108234567 LOC108239115 LOC108239115 podn podn LOC108244283 LOC108244283 nfya nfya LOC108230580 LOC108230580 LOC108230582 LOC108230582 LOC108250436 LOC108250436 dhcr24 dhcr24 CYP8B1 CYP8B1 LOC108241654 LOC108241654 LOC108235361 LOC108235361 LOC108243413 LOC108243413 nr1h4 nr1h4 nfyc nfyc osbpl7 osbpl7 LOC108233113 LOC108233113 ENSKMAP00000006692 ENSKMAP00000006692 insig2 insig2 ncoa1 ncoa1 pmvk pmvk sc5d sc5d LOC108231799 LOC108231799 SERPINA4 SERPINA4 LOC108246268 LOC108246268 LOC108234813 LOC108234813 hsd3b1 hsd3b1 lbr lbr LOC108248270 LOC108248270 pomc pomc srebf2 srebf2 dhcr7 dhcr7 idi1 idi1 hsd17b3 hsd17b3 LOC108246509 LOC108246509 mtf1 mtf1 OSBPL1A OSBPL1A ENSKMAP00000017856 ENSKMAP00000017856 amacr amacr ENSKMAP00000017228 ENSKMAP00000017228 LOC108230037 LOC108230037 LOC108240719 LOC108240719 insig1 insig1 fdft1 fdft1 LOC108244749 LOC108244749 ube2i ube2i LOC108232577 LOC108232577 LOC108244757 LOC108244757 LOC108240084 LOC108240084 LOC108229061 LOC108229061 tm7sf2 tm7sf2 ran ran ggps1 ggps1 nfyb nfyb LOC108238686 LOC108238686 ENSKMAP00000013340 ENSKMAP00000013340
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (400 aa)
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase. (410 aa)
LOC108232721Oxysterol-binding protein; Belongs to the OSBP family. (749 aa)
LOC108245380Retinol dehydrogenase 8b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
ENSKMAP00000011512Uncharacterized protein. (134 aa)
plpp6Phospholipid phosphatase 6. (277 aa)
tspoTranslocator protein. (161 aa)
LOC108234932Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (266 aa)
LOC108246358Uncharacterized protein. (216 aa)
hsdl2Hydroxysteroid dehydrogenase like 2. (405 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
ENSKMAP00000010114Hydroxysteroid (17-beta) dehydrogenase 14. (264 aa)
ncoa2Nuclear receptor coactivator. (1424 aa)
LOC108231375Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (505 aa)
ENSKMAP00000009203Solute carrier organic anion transporter family member. (596 aa)
LOC108233105Uncharacterized protein. (420 aa)
LOC108244039Solute carrier organic anion transporter family member. (697 aa)
LOC108230837Hydroxysteroid (17-beta) dehydrogenase 7. (222 aa)
mbtps1Membrane-bound transcription factor peptidase, site 1. (1077 aa)
hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
LOC108238278acidPPc domain-containing protein. (263 aa)
acot8Acyl-CoA thioesterase 8. (215 aa)
LOC108251651Dehydrogenase/reductase (SDR family) member 7Ca. (297 aa)
LOC108248082acidPPc domain-containing protein. (294 aa)
LOC108245161Luteinizing hormone, beta polypeptide. (164 aa)
srd5a3Steroid 5 alpha-reductase 3. (325 aa)
LOC108250404Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
LOC108231916Oxysterol-binding protein; Belongs to the OSBP family. (765 aa)
scp2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa)
msmo1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (291 aa)
LOC108229515Succinyl-CoA:glutarate-CoA transferase. (196 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (345 aa)
LOC108238813Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (537 aa)
LOC108251615Uncharacterized protein. (621 aa)
LOC108232148Oxysterol-binding protein; Belongs to the OSBP family. (481 aa)
LOC108250100Aldo_ket_red domain-containing protein. (326 aa)
ENSKMAP00000022691Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family. (267 aa)
LOC108232790Uncharacterized protein. (552 aa)
LOC108229945Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family. (280 aa)
LOC108235620Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (521 aa)
rxraRetinoid X receptor, alpha a. (496 aa)
LOC108241974Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (523 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (321 aa)
arv1ARV1 homolog, fatty acid homeostasis modulator. (251 aa)
LOC108236207UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
osbpl6Oxysterol-binding protein; Belongs to the OSBP family. (810 aa)
LOC108243744Retinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
sdr16c5Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
LOC1082425063-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (515 aa)
PLPP7Phospholipid phosphatase 7 (inactive). (300 aa)
ENSKMAP00000020812Uncharacterized protein. (341 aa)
ENSKMAP00000020705Uncharacterized protein. (373 aa)
LOC108245362Oxysterol-binding protein; Belongs to the OSBP family. (949 aa)
ch25hCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (252 aa)
LOC108247630START domain-containing protein. (264 aa)
LOC1082507293-hydroxy-3-methylglutaryl coenzyme A reductase. (881 aa)
LOC108231477Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
LOC108243127Solute carrier family 51 alpha subunit. (325 aa)
LOC108242023Oxysterol-binding protein; Belongs to the OSBP family. (841 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
LOC108251556Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (512 aa)
LOC108233144Oxysterol-binding protein; Belongs to the OSBP family. (472 aa)
LOC108231774Cytochrome p450 CYP46A1; Belongs to the cytochrome P450 family. (503 aa)
LOC108236565SERPIN domain-containing protein; Belongs to the serpin family. (394 aa)
ENSKMAP00000004088SERPIN domain-containing protein; Belongs to the serpin family. (131 aa)
LOC108236563SERPIN domain-containing protein; Belongs to the serpin family. (411 aa)
LOC108229396Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (615 aa)
ENSKMAP00000004016SERPIN domain-containing protein; Belongs to the serpin family. (179 aa)
SLCO1C1Solute carrier organic anion transporter family member. (689 aa)
LOC108247994Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (411 aa)
starSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (287 aa)
LOC108231838Cytochrome p450 CYP46A2. (504 aa)
LOC108231837Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
LOC112450290Uncharacterized protein. (508 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (490 aa)
sqleSqualene epoxidase a. (554 aa)
fdpsUncharacterized protein; Belongs to the FPP/GGPP synthase family. (360 aa)
LOC108250266Cytochrome P450, family 19, subfamily A, polypeptide 1a. (495 aa)
rusc1RUN and SH3 domain containing 1. (203 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
LOC108242722Small ubiquitin-related modifier. (96 aa)
LOC108247361Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (655 aa)
LOC108248515Oxysterol-binding protein; Belongs to the OSBP family. (772 aa)
ebplEBP like. (213 aa)
sdr42e1Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (387 aa)
SLC10A1Solute carrier family 10 member 1. (342 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (673 aa)
dhrs7cDehydrogenase/reductase (SDR family) member 7Cb. (313 aa)
LOC108239853Vitamin D receptor b. (425 aa)
LOC108247360Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (770 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (264 aa)
LOC108240983Aldo_ket_red domain-containing protein. (313 aa)
scapSREBF chaperone. (1359 aa)
stard3nlSTARD3 N-terminal like. (230 aa)
osbpl9Oxysterol-binding protein; Belongs to the OSBP family. (739 aa)
cubnCubilin (intrinsic factor-cobalamin receptor). (3620 aa)
LOC108250623Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (539 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (502 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (500 aa)
akr1b1Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
LOC108240996Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (316 aa)
LOC108243856Nuclear receptor coactivator. (1504 aa)
LOC108237530Zgc:56622. (386 aa)
Cdcp2CUB domain containing protein 2. (386 aa)
ptgisCytochrome p450 CYP8A1; Belongs to the cytochrome P450 family. (481 aa)
LOC108238612Fatty acid binding protein 6, ileal (gastrotropin). (127 aa)
LOC108238592Uncharacterized protein. (127 aa)
FABP6-2Fatty acid binding protein 6. (127 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
stard5StAR-related lipid transfer (START) domain containing 5. (212 aa)
ebpEBP cholestenol delta-isomerase. (229 aa)
stard3StAR-related lipid transfer (START) domain containing 3. (455 aa)
LOC108233374Acyl-CoA thioesterase 21. (417 aa)
LOC108233476Solute carrier family 10 member 1. (349 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1169 aa)
LOC108247306RIMS binding protein 2. (1694 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (356 aa)
adgrd1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (909 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (290 aa)
FADS6Fatty acid desaturase 6. (324 aa)
fdx2Ferredoxin 2. (196 aa)
LOC108229950Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (523 aa)
LOC108241911Oxysterol-binding protein; Belongs to the OSBP family. (830 aa)
LOC108237017Uncharacterized protein. (330 aa)
faxdc2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (344 aa)
LOC108234567Si:ch211-106a19.1. (753 aa)
LOC108239115Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (515 aa)
podnPodocan. (586 aa)
LOC108244283Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (530 aa)
nfyaNuclear transcription factor Y, alpha, like. (348 aa)
LOC108230580Hydroxysteroid (11-beta) dehydrogenase 1-like a. (287 aa)
LOC108230582Hydroxysteroid (11-beta) dehydrogenase 1-like a. (287 aa)
LOC108250436Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
dhcr2424-dehydrocholesterol reductase. (516 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
LOC108241654Uncharacterized protein; Belongs to the cytochrome P450 family. (509 aa)
LOC108235361Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
LOC108243413Oxysterol-binding protein; Belongs to the OSBP family. (975 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (486 aa)
nfycNuclear transcription factor Y, gamma. (356 aa)
osbpl7Oxysterol-binding protein; Belongs to the OSBP family. (862 aa)
LOC108233113Nuclear receptor subfamily 1, group H, member 5. (466 aa)
ENSKMAP00000006692AMP-binding domain-containing protein. (185 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (242 aa)
ncoa1Nuclear receptor coactivator 1. (1473 aa)
pmvkPhosphomevalonate kinase. (199 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (300 aa)
LOC108231799SERPIN domain-containing protein; Belongs to the serpin family. (407 aa)
SERPINA4Serpin family A member 4; Belongs to the serpin family. (417 aa)
LOC108246268Zgc:109982; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC108234813Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
hsd3b1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
lbrLamin B receptor. (619 aa)
LOC108248270Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
pomcProopiomelanocortin. (220 aa)
srebf2Sterol regulatory element binding transcription factor 2. (1175 aa)
dhcr77-dehydrocholesterol reductase. (472 aa)
idi1Isopentenyl-diphosphate delta isomerase 1. (287 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (323 aa)
LOC108246509Solute carrier organic anion transporter family member. (702 aa)
mtf1Metal-regulatory transcription factor 1. (804 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (991 aa)
ENSKMAP00000017856Uncharacterized protein. (852 aa)
amacrAlpha-methylacyl-CoA racemase. (382 aa)
ENSKMAP00000017228Uncharacterized protein. (928 aa)
LOC108230037Uncharacterized protein. (620 aa)
LOC108240719Small ubiquitin-related modifier. (94 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (252 aa)
fdft1Farnesyl-diphosphate farnesyltransferase 1. (452 aa)
LOC108244749Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family. (284 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC108232577Small ubiquitin-related modifier. (94 aa)
LOC1082447573-hydroxy-3-methylglutaryl coenzyme A reductase. (866 aa)
LOC108240084Uncharacterized protein. (216 aa)
LOC1082290613-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (257 aa)
tm7sf2Transmembrane 7 superfamily member 2. (425 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (219 aa)
ggps1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (315 aa)
nfybNuclear transcription factor Y, beta a. (204 aa)
LOC108238686Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (498 aa)
ENSKMAP00000013340Uncharacterized protein. (186 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
Server load: low (30%) [HD]