STRINGSTRING
rfc1 rfc1 RPA1 RPA1 cul4b cul4b gtf2h4 gtf2h4 ddb1 ddb1 xpc xpc pold2 pold2 pcna pcna ccnh ccnh rpa1 rpa1 rfc3 rfc3 mnat1 mnat1 LOC108240516 LOC108240516 LOC108248126 LOC108248126 pold4 pold4 rfc2 rfc2 gtf2h5 gtf2h5 rad23a rad23a pole3 pole3 pold1 pold1 pole2 pole2 rfc4 rfc4 cdk7 cdk7 rpa2 rpa2 ercc8 ercc8 rpa3 rpa3 rbx1 rbx1 Pole Pole pold3 pold3 lig1 lig1 gtf2h3 gtf2h3 ddb2 ddb2 ercc6 ercc6 ercc1 ercc1 xpa xpa gtf2h1 gtf2h1 ercc2 ercc2 ercc3 ercc3 ercc4 ercc4 LOC108232507 LOC108232507 LOC108229807 LOC108229807 ercc5 ercc5 pole4 pole4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc1Replication factor C subunit 1. (1180 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
cul4bCullin 4B; Belongs to the cullin family. (869 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
ddb1Damage-specific DNA binding protein 1. (1075 aa)
xpcXeroderma pigmentosum, complementation group C. (935 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ccnhCyclin H; Belongs to the cyclin family. (333 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
LOC108240516Centrin, EF-hand protein, 2. (177 aa)
LOC108248126RPA_C domain-containing protein. (199 aa)
pold4Uncharacterized protein. (110 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (365 aa)
pole3CBFD_NFYB_HMF domain-containing protein. (153 aa)
pold1DNA polymerase. (1105 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rfc4Replication factor C (activator 1) 4. (388 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
rpa2RPA_C domain-containing protein. (274 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
rpa3Replication protein A 14kDa subunit. (122 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (298 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa)
lig1DNA ligase. (1010 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (299 aa)
ddb2Damage-specific DNA binding protein 2. (497 aa)
ercc6Excision repair cross-complementation group 6. (1442 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (409 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
LOC108232507General transcription factor IIH subunit. (392 aa)
LOC108229807Cullin 4A; Belongs to the cullin family. (746 aa)
ercc5Excision repair cross-complementation group 5. (1028 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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