node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC108248126 | RPA1 | ENSKMAP00000010056 | ENSKMAP00000000242 | RPA_C domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.990 |
LOC108248126 | lig1 | ENSKMAP00000010056 | ENSKMAP00000022977 | RPA_C domain-containing protein. | DNA ligase. | 0.754 |
LOC108248126 | mlh1 | ENSKMAP00000010056 | ENSKMAP00000011476 | RPA_C domain-containing protein. | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). | 0.499 |
LOC108248126 | msh2 | ENSKMAP00000010056 | ENSKMAP00000015699 | RPA_C domain-containing protein. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.714 |
LOC108248126 | msh6 | ENSKMAP00000010056 | ENSKMAP00000022133 | RPA_C domain-containing protein. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.818 |
LOC108248126 | pcna | ENSKMAP00000010056 | ENSKMAP00000003800 | RPA_C domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.882 |
LOC108248126 | pms2 | ENSKMAP00000010056 | ENSKMAP00000011431 | RPA_C domain-containing protein. | PMS1 homolog 2, mismatch repair system component. | 0.479 |
LOC108248126 | pold1 | ENSKMAP00000010056 | ENSKMAP00000013397 | RPA_C domain-containing protein. | DNA polymerase. | 0.727 |
LOC108248126 | pold2 | ENSKMAP00000010056 | ENSKMAP00000003731 | RPA_C domain-containing protein. | Polymerase (DNA directed), delta 2, regulatory subunit. | 0.693 |
LOC108248126 | rfc1 | ENSKMAP00000010056 | ENSKMAP00000000045 | RPA_C domain-containing protein. | Replication factor C subunit 1. | 0.726 |
LOC108248126 | rfc2 | ENSKMAP00000010056 | ENSKMAP00000011442 | RPA_C domain-containing protein. | Replication factor C (activator 1) 2. | 0.864 |
LOC108248126 | rfc3 | ENSKMAP00000010056 | ENSKMAP00000007640 | RPA_C domain-containing protein. | Replication factor C (activator 1) 3. | 0.809 |
LOC108248126 | rfc4 | ENSKMAP00000010056 | ENSKMAP00000015449 | RPA_C domain-containing protein. | Replication factor C (activator 1) 4. | 0.801 |
LOC108248126 | rpa1 | ENSKMAP00000010056 | ENSKMAP00000007505 | RPA_C domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.990 |
LOC108248126 | rpa2 | ENSKMAP00000010056 | ENSKMAP00000017804 | RPA_C domain-containing protein. | RPA_C domain-containing protein. | 0.904 |
LOC108248126 | rpa3 | ENSKMAP00000010056 | ENSKMAP00000019992 | RPA_C domain-containing protein. | Replication protein A 14kDa subunit. | 0.994 |
RPA1 | LOC108248126 | ENSKMAP00000000242 | ENSKMAP00000010056 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | RPA_C domain-containing protein. | 0.990 |
RPA1 | lig1 | ENSKMAP00000000242 | ENSKMAP00000022977 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA ligase. | 0.720 |
RPA1 | mlh1 | ENSKMAP00000000242 | ENSKMAP00000011476 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). | 0.664 |
RPA1 | msh2 | ENSKMAP00000000242 | ENSKMAP00000015699 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.816 |