93 items (Kryptolebias marmoratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108241005	Cyclin-dependent kinase inhibitor 1D. (175 aa)
	LOC108238123	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (496 aa)
	LOC108250222	PH domain-containing protein. (704 aa)
	LOC108251479	BHLH domain-containing protein. (370 aa)
	LOC108240964	Uncharacterized protein. (240 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	LOC108230757	SHC (Src homology 2 domain containing) transforming protein 2. (738 aa)
	nck2	Cytoplasmic protein. (396 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
	LOC108250884	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
	LOC108239982	HRas proto-oncogene, GTPase a. (189 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
	LOC108237634	Tyrosine-protein kinase. (549 aa)
	LOC108235888	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
	LOC108244154	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	egfr	Receptor protein-tyrosine kinase. (1196 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	erbb4	Receptor protein-tyrosine kinase. (1407 aa)
	LOC108238174	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	LOC108248584	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	gab1	GRB2-associated binding protein 1. (786 aa)
	ENSKMAP00000005163	Uncharacterized protein. (495 aa)
	LOC108251591	CRIB domain-containing protein. (99 aa)
	KRAS	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC108246299	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC108240588	Mitogen-activated protein kinase. (420 aa)
	LOC108238336	Uncharacterized protein. (470 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	LOC108234365	Uncharacterized protein. (426 aa)
	LOC108233667	Amphiregulin. (233 aa)
	LOC108235495	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
	LOC108245177	Signal transducer and activator of transcription. (788 aa)
	LOC108230652	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	tgfa	Transforming growth factor, alpha. (242 aa)
	ENSKMAP00000011188	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (319 aa)
	ENSKMAP00000011338	Protein kinase domain-containing protein. (110 aa)
	LOC108238424	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC108248149	V-crk avian sarcoma virus CT10 oncogene homolog. (307 aa)
	LOC108242980	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	LOC108243005	Zgc:55558. (187 aa)
	egf	Epidermal growth factor. (1111 aa)
	LOC108249882	A-Raf proto-oncogene, serine/threonine kinase. (608 aa)
	LOC108247561	Uncharacterized protein. (456 aa)
	LOC108248045	Protein kinase domain-containing protein. (616 aa)
	braf	B-Raf proto-oncogene, serine/threonine kinase. (778 aa)
	LOC108245882	Uncharacterized protein. (717 aa)
	nck1	Cytoplasmic protein. (393 aa)
	LOC108236256	Growth factor receptor-bound protein 2b. (224 aa)
	LOC108231089	Betacellulin, epidermal growth factor family member. (184 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (316 aa)
	raf1	Raf-1 proto-oncogene, serine/threonine kinase a. (677 aa)
	LOC108232646	Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
	LOC108238002	Neuregulin 2b. (563 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	SHC3	SHC adaptor protein 3. (671 aa)
	LOC108246548	CRK proto-oncogene, adaptor protein. (310 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	LOC108237117	Non-specific serine/threonine protein kinase. (696 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	LOC108249494	Myelocytomatosis oncogene homolog. (367 aa)
	LOC108244269	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1. (512 aa)
	LOC108244850	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (723 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
	camk2b	Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (539 aa)
	LOC108246606	Cyclin-dependent kinase inhibitor 1Bb. (204 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
	pak1	Non-specific serine/threonine protein kinase. (566 aa)
	nrg4	EGF-like domain-containing protein. (106 aa)
	abl1	Tyrosine-protein kinase. (1121 aa)
	LOC108238085	Uncharacterized protein. (881 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
	eif4ebp1	Uncharacterized protein. (119 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
	ENSKMAP00000024758	EGF-like domain-containing protein. (118 aa)
	LOC108242040	Heparin-binding EGF-like growth factor a. (234 aa)
	LOC108239241	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (450 aa)
	erbb3	Protein kinase domain-containing protein. (1419 aa)
	LOC108243254	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
	LOC108243804	Signal transducer and activator of transcription. (791 aa)
	LOC108234067	Mitogen-activated protein kinase. (411 aa)
	LOC108248942	Receptor protein-tyrosine kinase. (1296 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1231 aa)
	ENSKMAP00000028735	Protein kinase domain-containing protein. (114 aa)
	LOC112450491	Cyclin-dependent kinase inhibitor 1A. (159 aa)
	LOC108235300	Erb-b2 receptor tyrosine kinase 3b. (1454 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
	LOC108236992	Neuregulin 2a. (707 aa)
	abl2	Tyrosine-protein kinase. (1203 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSKMAP00000005163	KRAS	ENSKMAP00000005163	ENSKMAP00000005296	Uncharacterized protein.	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family.	0.760
ENSKMAP00000005163	LOC108230757	ENSKMAP00000005163	ENSKMAP00000000742	Uncharacterized protein.	SHC (Src homology 2 domain containing) transforming protein 2.	0.962
ENSKMAP00000005163	LOC108231089	ENSKMAP00000005163	ENSKMAP00000017182	Uncharacterized protein.	Betacellulin, epidermal growth factor family member.	0.955
ENSKMAP00000005163	LOC108233667	ENSKMAP00000005163	ENSKMAP00000007446	Uncharacterized protein.	Amphiregulin.	0.916
ENSKMAP00000005163	LOC108234365	ENSKMAP00000005163	ENSKMAP00000007170	Uncharacterized protein.	Uncharacterized protein.	0.797
ENSKMAP00000005163	LOC108236256	ENSKMAP00000005163	ENSKMAP00000017060	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.981
ENSKMAP00000005163	LOC108236992	ENSKMAP00000005163	ENSKMAP00000030024	Uncharacterized protein.	Neuregulin 2a.	0.659
ENSKMAP00000005163	LOC108237634	ENSKMAP00000005163	ENSKMAP00000002899	Uncharacterized protein.	Tyrosine-protein kinase.	0.951
ENSKMAP00000005163	LOC108238002	ENSKMAP00000005163	ENSKMAP00000019056	Uncharacterized protein.	Neuregulin 2b.	0.659
ENSKMAP00000005163	LOC108238085	ENSKMAP00000005163	ENSKMAP00000023932	Uncharacterized protein.	Uncharacterized protein.	0.970
ENSKMAP00000005163	LOC108238336	ENSKMAP00000005163	ENSKMAP00000007059	Uncharacterized protein.	Uncharacterized protein.	0.797
ENSKMAP00000005163	LOC108238424	ENSKMAP00000005163	ENSKMAP00000011820	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.788
ENSKMAP00000005163	LOC108239982	ENSKMAP00000005163	ENSKMAP00000002614	Uncharacterized protein.	HRas proto-oncogene, GTPase a.	0.485
ENSKMAP00000005163	LOC108242040	ENSKMAP00000005163	ENSKMAP00000025271	Uncharacterized protein.	Heparin-binding EGF-like growth factor a.	0.963
ENSKMAP00000005163	LOC108243005	ENSKMAP00000005163	ENSKMAP00000013546	Uncharacterized protein.	Zgc:55558.	0.518
ENSKMAP00000005163	LOC108243804	ENSKMAP00000005163	ENSKMAP00000026896	Uncharacterized protein.	Signal transducer and activator of transcription.	0.944
ENSKMAP00000005163	LOC108244850	ENSKMAP00000005163	ENSKMAP00000021593	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.797
ENSKMAP00000005163	LOC108245177	ENSKMAP00000005163	ENSKMAP00000007917	Uncharacterized protein.	Signal transducer and activator of transcription.	0.944
ENSKMAP00000005163	LOC108245882	ENSKMAP00000005163	ENSKMAP00000014776	Uncharacterized protein.	Uncharacterized protein.	0.797
ENSKMAP00000005163	LOC108246548	ENSKMAP00000005163	ENSKMAP00000020188	Uncharacterized protein.	CRK proto-oncogene, adaptor protein.	0.928