STRINGSTRING
LOC108230762 LOC108230762 map2k7 map2k7 LOC108245617 LOC108245617 adcy2 adcy2 adcy7 adcy7 adcy8 adcy8 calml4 calml4 LOC108241594 LOC108241594 LOC108228616 LOC108228616 LOC108239982 LOC108239982 LOC108237634 LOC108237634 LOC108234775 LOC108234775 LOC108235888 LOC108235888 LOC108251551 LOC108251551 egfr egfr map2k2 map2k2 Itpr3 Itpr3 calm1 calm1 LOC108247381 LOC108247381 ENSKMAP00000005163 ENSKMAP00000005163 KRAS KRAS map3k2 map3k2 LOC108248619 LOC108248619 itpr2 itpr2 mapk1 mapk1 LOC108240588 LOC108240588 LOC108233125 LOC108233125 egr1 egr1 LOC108248645 LOC108248645 adcy5 adcy5 LOC108245161 LOC108245161 LOC108244602 LOC108244602 ENSKMAP00000008201 ENSKMAP00000008201 LOC108230652 LOC108230652 LOC108244594 LOC108244594 LOC108251695 LOC108251695 LOC108242882 LOC108242882 LOC108233159 LOC108233159 LOC108251047 LOC108251047 CDC42 CDC42 LOC108235453 LOC108235453 LOC108235454 LOC108235454 ENSKMAP00000011188 ENSKMAP00000011188 cga cga LOC108242980 LOC108242980 ENSKMAP00000013318 ENSKMAP00000013318 LOC108243005 LOC108243005 prkacb prkacb LOC108248045 LOC108248045 LOC108231541 LOC108231541 LOC108230337 LOC108230337 LOC108241241 LOC108241241 LOC108245890 LOC108245890 adcy6 adcy6 GNAS GNAS LOC108230976 LOC108230976 LOC108236256 LOC108236256 LOC108229092 LOC108229092 pla2g4a pla2g4a LOC108241350 LOC108241350 LOC108231696 LOC108231696 ptk2b ptk2b LOC108235078 LOC108235078 raf1 raf1 LOC108248273 LOC108248273 LOC108248262 LOC108248262 ADCY9 ADCY9 LOC108239683 LOC108239683 SRC SRC PLCB2 PLCB2 LOC108239664 LOC108239664 pla2g4c pla2g4c LOC108244269 LOC108244269 mapk7 mapk7 LOC108229969 LOC108229969 camk2b camk2b LOC108236059 LOC108236059 LOC108237387 LOC108237387 mmp2 mmp2 PRKCA PRKCA LOC108248366 LOC108248366 LOC108249551 LOC108249551 map3k4 map3k4 adcy3 adcy3 PRKCB PRKCB LOC108235741 LOC108235741 prkaca prkaca LOC108242040 LOC108242040 gnrh2 gnrh2 LOC108239241 LOC108239241 map2k1 map2k1 LOC108243254 LOC108243254 LOC108241462 LOC108241462 prkcd prkcd LOC108232311 LOC108232311 LOC108234608 LOC108234608 mmp14 mmp14 LOC108250188 LOC108250188 LOC108245287 LOC108245287 itpr1 itpr1 LOC108234067 LOC108234067 LOC108237567 LOC108237567
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108230762Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
LOC108245617Mitogen-activated protein kinase kinase 6. (358 aa)
adcy2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
adcy8Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1269 aa)
calml4Calmodulin-like 4a. (153 aa)
LOC108241594G_PROTEIN_RECEP_F1_2 domain-containing protein. (400 aa)
LOC108228616Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (155 aa)
LOC108239982HRas proto-oncogene, GTPase a. (189 aa)
LOC108237634Tyrosine-protein kinase. (549 aa)
LOC108234775Follicle stimulating hormone beta subunit. (120 aa)
LOC108235888Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
LOC108251551Uncharacterized protein. (408 aa)
egfrReceptor protein-tyrosine kinase. (1196 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
Itpr3Uncharacterized protein. (663 aa)
calm1Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC108247381Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2058 aa)
ENSKMAP00000005163Uncharacterized protein. (495 aa)
KRASGTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). Belongs to the small GTPase superfamily. Ras family. (189 aa)
map3k2Mitogen-activated protein kinase kinase kinase 2. (633 aa)
LOC108248619Uncharacterized protein. (1285 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2649 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC108240588Mitogen-activated protein kinase. (420 aa)
LOC108233125Mitogen-activated protein kinase. (363 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
LOC108248645Cell division cycle 42. (191 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1202 aa)
LOC108245161Luteinizing hormone, beta polypeptide. (164 aa)
LOC108244602Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1182 aa)
ENSKMAP00000008201Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (647 aa)
LOC108230652Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
LOC108244594Mitogen-activated protein kinase. (359 aa)
LOC108251695Uncharacterized protein. (430 aa)
LOC1082428821-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1180 aa)
LOC108233159Mitogen-activated protein kinase. (364 aa)
LOC108251047Mitogen-activated protein kinase. (361 aa)
CDC42Cell division cycle 42. (197 aa)
LOC108235453Uncharacterized protein. (197 aa)
LOC108235454Uncharacterized protein. (190 aa)
ENSKMAP00000011188Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (319 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (151 aa)
LOC108242980Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (408 aa)
ENSKMAP00000013318Protein kinase domain-containing protein. (108 aa)
LOC108243005Zgc:55558. (187 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC108248045Protein kinase domain-containing protein. (616 aa)
LOC108231541Activating transcription factor 4a. (448 aa)
LOC108230337Mitogen-activated protein kinase kinase kinase 22. (623 aa)
LOC108241241Protein kinase domain-containing protein. (337 aa)
LOC108245890Matrix metallopeptidase 14a (membrane-inserted). (556 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
GNASGNAS complex locus. (379 aa)
LOC108230976G protein subunit alpha q. (359 aa)
LOC108236256Growth factor receptor-bound protein 2b. (224 aa)
LOC108229092Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (814 aa)
pla2g4aPhospholipase A2. (747 aa)
LOC108241350Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
LOC108231696GNAS complex locus. (379 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (993 aa)
LOC108235078Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (677 aa)
LOC108248273Phospholipase. (953 aa)
LOC108248262Phospholipase. (1010 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1435 aa)
LOC108239683Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1180 aa)
SRCTyrosine-protein kinase. (550 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
LOC108239664Uncharacterized protein; Belongs to the protein kinase superfamily. (349 aa)
pla2g4cPLA2c domain-containing protein. (552 aa)
LOC108244269Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1. (512 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1108 aa)
LOC108229969G_PROTEIN_RECEP_F1_2 domain-containing protein. (406 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (539 aa)
LOC108236059Activating transcription factor 4b. (444 aa)
LOC108237387G_PROTEIN_RECEP_F1_2 domain-containing protein. (420 aa)
mmp2Matrix metallopeptidase 2. (657 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
LOC108248366Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1125 aa)
LOC108249551Phospholipase. (1038 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1590 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC108235741Inositol 1,4,5-trisphosphate receptor, type 1a. (2655 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC108242040Heparin-binding EGF-like growth factor a. (234 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (84 aa)
LOC108239241Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (450 aa)
LOC108243254Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
LOC108241462Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1457 aa)
prkcdProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
LOC108232311Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1199 aa)
LOC108234608Uncharacterized protein. (359 aa)
mmp14Matrix metallopeptidase 14b (membrane-inserted). (605 aa)
LOC108250188G_PROTEIN_RECEP_F1_2 domain-containing protein. (378 aa)
LOC108245287Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (90 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2724 aa)
LOC108234067Mitogen-activated protein kinase. (411 aa)
LOC108237567Mitogen-activated protein kinase. (361 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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