STRINGSTRING
A8MQG8_ARATH A8MQG8_ARATH POLIA POLIA RECG RECG WHY3 WHY3 MSH1 MSH1 POLIB POLIB OSB3 OSB3 RECA3 RECA3 WHY2 WHY2 OSB1 OSB1 RECA2 RECA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A8MQG8_ARATH5'-3' exonuclease family protein. (448 aa)
POLIADNA polymerase I A, chloroplastic/mitochondrial; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria. May be required for DNA repair in both organelles; Belongs to the DNA polymerase type-A family. (1050 aa)
RECGATP-dependent DNA helicase homolog RECG, chloroplastic; Critical role in recombination and DNA repair. (973 aa)
WHY3Single-stranded DNA-binding protein WHY3, chloroplastic; Single-stranded DNA-binding protein that functions in both chloroplasts and nucleus. In chloroplasts, maintains plastid genome stability by preventing break-induced and short homology-dependent illegitimate recombinations. In the nucleus, is recruited to a distal element upstream of the kinesin KP1 to mediate the transcriptional repression of KP1. Can bind double-stranded DNA in vivo. (268 aa)
MSH1DNA mismatch repair protein MSH1, mitochondrial; DNA mismatch repair protein specifically involved in maintenance of mitochondrial genome configuration by controlling specific rearranged portion. Functions by suppressing asymmetric recombination at some repeat pairs. (1118 aa)
POLIBDNA polymerase I B, chloroplastic/mitochondrial; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria. (1034 aa)
OSB3Protein OSB3, chloroplastic/mitochondrial; Binds single-stranded DNA. (440 aa)
RECA3DNA repair protein recA homolog 2, mitochondrial; Involved in recombination ability and DNA strand transfer activity; Belongs to the RecA family. (389 aa)
WHY2Single-stranded DNA-binding protein WHY2, mitochondrial; Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery. Seems also to be required to prevent break- induced DNA rearrangements in the mitochondrial genome. Can bind to melt double-stranded DNA in vivo. (238 aa)
OSB1Protein OSB1, mitochondrial; Regulates mitochondrial DNA recombination. Represses homologous recombination, preventing mitochondrial genome instability and unbalanced transmission of alternative mtDNA configurations. Binds preferentially single-stranded DNA. Does not bind to RNA. (261 aa)
RECA2DNA repair protein recA homolog 3, mitochondrial; Involved in recombination ability and DNA strand transfer activity; Belongs to the RecA family. (430 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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