STRINGSTRING
HEB1 HEB1 SCC2 SCC2 CTF7 CTF7 B3H5K3_ARATH B3H5K3_ARATH T5M16.19 T5M16.19 AtWAPL1 AtWAPL1 F4J1Q3_ARATH F4J1Q3_ARATH F4J246_ARATH F4J246_ARATH EMB2656 EMB2656 GIL1 GIL1 dl3985w dl3985w CAPH CAPH SMC3 SMC3 MAPKKK21 MAPKKK21 SMC1 SMC1 SYN4 SYN4 SMC2-1 SMC2-1 AtWAPL2 AtWAPL2 SCC4 SCC4 SMC4 SMC4 SYN3 SYN3 SYN2 SYN2 CAPH2 CAPH2 SYN1 SYN1 SMC2-2 SMC2-2 F12A24.8 F12A24.8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HEB1ARM repeat superfamily protein. (1232 aa)
SCC2Sister chromatid cohesion protein SCC2; Essential protein required for cell fate determination during embryogenesis. Involved in sister chromatid cohesion during meiosis and mitosis. Forms a complex with SCC4, which is required for the association of the cohesin complex with chromosomes. Plays a structural role in chromatin, especially in centromere organization, chromosomal axis formation, and distribution of the cohesin subunit SCC3 on chromosomes. (1846 aa)
CTF7Protein CHROMOSOME TRANSMISSION FIDELITY 7; Acetyltransferase required for the establishment of sister chromatid cohesion. Involved in preservation of genome integrity and meiosis. Required for DNA repair and for the regulation of chromosome segregation during mitotic cell division. Knock-down mutants are extremely dwarf. (345 aa)
B3H5K3_ARATHBinding protein. (1607 aa)
T5M16.19ARM repeat superfamily protein. (1424 aa)
AtWAPL1WAPL (Wings apart-like protein regulation of heterochromatin) protein. (930 aa)
F4J1Q3_ARATHStructural maintenance of chromosomes protein. (247 aa)
F4J246_ARATHCondensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1415 aa)
EMB2656ARM repeat superfamily protein. (1051 aa)
GIL1Protein GRAVITROPIC IN THE LIGHT 1; Required for red (R) and far red (FR) light-induced and phytochrome-mediated deregulation of negative gravitropism leading to randomization of hypocotyl growth orientation. (559 aa)
dl3985wCondensin-2 complex subunit. (1314 aa)
CAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). Essential protein. (671 aa)
SMC3Structural maintenance of chromosomes protein 3; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity). Essential protein plant viabili [...] (1204 aa)
MAPKKK21Mitogen-activated protein kinase kinase kinase 21; Belongs to the protein kinase superfamily. (336 aa)
SMC1Structural maintenance of chromosomes protein 1; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity). Essential protein plant viabili [...] (1218 aa)
SYN4Sister chromatid cohesion 1 protein 4; Involved in sister chromatid and centromere cohesion during mitosis. (1031 aa)
SMC2-1Structural maintenance of chromosomes protein 2-1; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis. (1175 aa)
AtWAPL2WAPL (Wings apart-like protein regulation of heterochromatin) protein. (840 aa)
SCC4Sister chromatid cohesion protein SCC4; Essential protein required for cell fate determination during embryogenesis. Involved in sister chromatid cohesion. Forms a complex with SCC2, which is required for the association of the cohesin complex with chromosomes. (726 aa)
SMC4Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis; Belongs to the SMC family. SMC4 subfamily. (1241 aa)
SYN3Sister chromatid cohesion 1 protein 3; May be involved in sister chromatid cohesion during mitosis. (693 aa)
SYN2Sister chromatid cohesion 1 protein 2; May be involved in sister chromatid cohesion during mitosis; Belongs to the rad21 family. (810 aa)
CAPH2Condensin-2 complex subunit H2; Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (By similarity). The condensin-2 complex plays a role in DNA damage repair or in protecting the genome from certain genotoxic stressors (e.g. boron excess, zeocin and aphidicolin); Belongs to the CND2 H2 (condensin-2 subunit 2) family. (683 aa)
SYN1Sister chromatid cohesion 1 protein 1; Involved in chromosome condensation, pairing and segregation during meiosis. Responsible for cohesion between replicated sister chromatids. (627 aa)
SMC2-2Structural maintenance of chromosomes protein 2-2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis. (1171 aa)
F12A24.8Phospholipase-like protein (PEARLI 4) family protein. (382 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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