STRINGSTRING
Dl3755W Dl3755W UFD1 UFD1 PUX6 PUX6 PUX8 PUX8 T9J23.1 T9J23.1 CDC48A CDC48A PUX5 PUX5 PUX4 PUX4 PUX15 PUX15 PUX7 PUX7 PUX13 PUX13 Q9LHN3_ARATH Q9LHN3_ARATH PUX1 PUX1 OTU2 OTU2 NPL41 NPL41 CDC48E CDC48E F13M7.16 F13M7.16 CDC48D CDC48D PUX3 PUX3 F19H22.30 F19H22.30 PUX2 PUX2 PUX11 PUX11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dl3755WUbiquitin fusion degradation UFD1 family protein. (684 aa)
UFD1Ubiquitin fusion degradation 1. (340 aa)
PUX6Plant UBX domain-containing protein 6. (435 aa)
PUX8Plant UBX domain-containing protein 8. (564 aa)
T9J23.1NPL4-like protein 2; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. (413 aa)
CDC48ACell division control protein 48 homolog A; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity). (809 aa)
PUX5Plant UBX domain-containing protein 5. (421 aa)
PUX4Plant UBX domain-containing protein 4. (303 aa)
PUX15Putative plant UBX domain-containing protein 15. (359 aa)
PUX7Plant UBX domain-containing protein 7; Acts as a bridge between CDC48A and ubiquitin, suggesting a role in targeted protein degradation. (468 aa)
PUX13Plant UBX domain-containing protein 13. (525 aa)
Q9LHN3_ARATHTransducin family protein / WD-40 repeat family protein. (760 aa)
PUX1Plant UBX domain-containing protein 1; Regulates CDC48A by inhibiting its ATPase activity and by promoting the disassembly of the active hexamer. (251 aa)
OTU2OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Cysteine protease with a preference for 'Lys-63' and 'Lys-48' -linked ubiquitin (UB) tetramers as substrates. Belongs to the peptidase C85 family. (208 aa)
NPL41NPL4-like protein 1; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. Belongs to the NPL4 family. (413 aa)
CDC48ECell division control protein 48 homolog E; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (810 aa)
F13M7.16Ubiquitin-associated (UBA)/TS-N domain-containing protein. (413 aa)
CDC48DCell division control protein 48 homolog D; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (815 aa)
PUX3Plant UBX domain-containing protein 3. (302 aa)
F19H22.30Putative ubiquitin-dependent proteolytic protein. (315 aa)
PUX2Plant UBX domain-containing protein 2; Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function. Appears to act as a negative regulator mediating the powdery mildew-plant interaction. (458 aa)
PUX11Plant UBX domain-containing protein 11. (531 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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