Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...]

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphingolipid delta(4)-desaturase DES1-like; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. May play a minor role in maintenance of sphingolipid metabolism during normal plant development and growth, but be required for maintaining sphingoid long chain bases (LCB) and their phosphorylated derivatives (LCB-P) levels when sphingolipid metabolism is perturbed. May play a role in dehydration stress.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Pyridoxal phosphate (PLP)-dependent transferases superfamily protein.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

LAG1 longevity assurance homolog 2; Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis. Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity).

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Long chain base biosynthesis protein 1; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Long chain base biosynthesis protein 2a; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphingoid long-chain bases kinase 2, mitochondrial; Involved in the production of sphingoid long-chain base (LCB). Is required for the cold-induced accumulation of phytosphingosine-phosphate, the regulation of the cold-responsive MPK6 and reduction of root growth at moderate low temperature.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Uncharacterized CRM domain-containing protein At3g25440, chloroplastic.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Lipid phosphate phosphatase delta; Functions as sphingoid long-chain base phosphate (LCBP) phosphatase. May play a role in the regulation of LCBP levels and be involved in stomatal responses through LCBP-mediated ABA signaling. Belongs to the type 2 lipid phosphate phosphatase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Neutral ceramidase 1; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Regulates sphingolipid homeostasis. Promotes oxidative stress resistance; Belongs to the neutral ceramidase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Neutral ceramidase 2; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the neutral ceramidase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Neutral ceramidase 3; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid (By similarity). Promotes oxidative stress resistance.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphinganine C4-monooxygenase 1; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino- 1,3,4-trihydroxyoctadecane and -eicosane). Belongs to the sterol desaturase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphinganine C4-monooxygenase 2; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino- 1,3,4-trihydroxyoctadecane and -eicosane). Belongs to the sterol desaturase family.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Delta(8)-fatty-acid desaturase 2; Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position. The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio). This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides. Sphingolipids are important membrane components involved in environmental stress responses, such as resista [...]

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphingosine kinase 1; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4-hydroxysphinganine), 4- hydroxy-8-sphingenine, 4,8-sphingadienine, D-erythro-dihydrosphingosine and D,L-threo-dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA that mediates stomatal closure.

Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).

Sphingosine kinase 2; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various l sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4-hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-erythro- dihydrosphingosine, but has a very few activity toward D,L- threo- dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA tha [...]