node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACER | CERK | Q94IB9 | Q6USK2 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | 0.920 |
ACER | DES-1-LIKE | Q94IB9 | Q9ZPH4 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Sphingolipid delta(4)-desaturase DES1-like; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides. | 0.944 |
ACER | F14M2.16 | Q94IB9 | F4HR96 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.719 |
ACER | F28M11.3 | Q94IB9 | F4JLJ2 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.723 |
ACER | F4JF53_ARATH | Q94IB9 | F4JF53 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Pyridoxal phosphate (PLP)-dependent transferases superfamily protein. | 0.929 |
ACER | LCB1 | Q94IB9 | Q94IB8 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Long chain base biosynthesis protein 1; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis. | 0.949 |
ACER | LCB2a | Q94IB9 | Q9LSZ9 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Long chain base biosynthesis protein 2a; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.931 |
ACER | NCER1 | Q94IB9 | F4HQM3 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Neutral ceramidase 1; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Regulates sphingolipid homeostasis. Promotes oxidative stress resistance; Belongs to the neutral ceramidase family. | 0.992 |
ACER | NCER2 | Q94IB9 | Q304B9 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Neutral ceramidase 2; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the neutral ceramidase family. | 0.978 |
ACER | NCER3 | Q94IB9 | F4KHQ8 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Neutral ceramidase 3; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid (By similarity). Promotes oxidative stress resistance. | 0.979 |
ACER | SBH1 | Q94IB9 | Q8VYI1 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Sphinganine C4-monooxygenase 1; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino- 1,3,4-trihydroxyoctadecane and -eicosane). Belongs to the sterol desaturase family. | 0.978 |
ACER | SPHK2 | Q94IB9 | F2Y4A3 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | Sphingosine kinase 2; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various l sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4-hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-erythro- dihydrosphingosine, but has a very few activity toward D,L- threo- dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA tha [...] | 0.988 |
ACER | TSC10A | Q94IB9 | Q0WRJ2 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | 3-dehydrosphinganine reductase TSC10A; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Lacks stereospecificity and can also produce L-threo-DHS in addition to D- erythro-DHS; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.978 |
ACER | TSC10B | Q94IB9 | F4JZN6 | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | 3-dehydrosphinganine reductase TSC10B; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Is stereospecific for D-erythro-DHS production and does not produce L-threo-DHS. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.980 |
CERK | ACER | Q6USK2 | Q94IB9 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Alkaline ceramidase; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1). | 0.920 |
CERK | DES-1-LIKE | Q6USK2 | Q9ZPH4 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Sphingolipid delta(4)-desaturase DES1-like; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides. | 0.937 |
CERK | F14M2.16 | Q6USK2 | F4HR96 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.972 |
CERK | F28M11.3 | Q6USK2 | F4JLJ2 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.974 |
CERK | F4JF53_ARATH | Q6USK2 | F4JF53 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Pyridoxal phosphate (PLP)-dependent transferases superfamily protein. | 0.926 |
CERK | LCB1 | Q6USK2 | Q94IB8 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Possesses high activity on ceramide analogs (C6, C8 synthetic ceramides) and lower activity on C6 and C8 dihydroceramides. Has weak activity on natural ceramides (a mixture of ceramides from bovine brain) and the synthetic substrate C2 ceramide. Has very poor activity on diacylglycerol and sphingosine. Ceramide is a critical sphingolipid metabolite that induces programmed cell death (PCD) in plants and ceramide-1-phosphate has a PCD suppressive effect. Thus, ceramide phosphorylation pl [...] | Long chain base biosynthesis protein 1; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis. | 0.953 |